Abstract Solar energy, as main energy supply that sustains life on Earth, is also an unavoidable component of the complex strategy in achieving a clean and fair energy transition and goals for sustainable development by 2030. The present work studies the potential of installing Photovoltaic Distributed Generation at Universidad Politecnica de Madrid – Ciudad Universitaria campus. To this end, the study focuses on the electricity generation, carbon reduction and economic feasibility of solar photovoltaic systems installation using and comparing two different approaches based on data input with different time resolution, simulation software and level of details. Results show that the optimal photovoltaic power that maximizes emissions savings also ensures the best economic return, and in addition coincides with the maximum solar potential of the Campus, which is about 3.3 MW. At campus level, approximately 77% of the photovoltaic electricity production would be consumed locally, which would suppose a coverage of about 40% of the total electricity consumption. Emissions savings could reach 30% and an in-depth economic analysis indicates that the project is highly profitable. These results and methodology could be used to assess the feasibility of photovoltaic systems at other universities and help entities study the solar potential of their buildings.