Today, the use of renewable energies in buildings represents one of the main ways to reach a sustainable world. Whilst present buildings are still often energivorous systems, in the near future they will have to be converted to (or replaced by) zero energy buildings, also capable to export green energy (produced on-site by renewables) towards other buildings and/or users. This review article focuses on a selection of research papers, presented at the 16th International Conference on Building Simulation (BS 2019), regarding renewable energy applications, energy saving and comfort techniques for buildings. BS 2019 conference was organized in collaboration with the International Building Performance Simulation Association (IBPSA) and it was held at the Angelicum Congress Centre (San Tommaso d’Aquino Pontifex University) in Rome, Italy, during September 2-4, 2019. The conference was attended by 912 researchers and experts, with 660 presented research papers. The above-mentioned selection of papers is included in a dedicated Special Issue of the Renewable Energy - An International Journal (RENE), titled “Renewable energies: simulation tools and applications”. Reported studies are mostly dedicated to models, simulations, and optimization procedures of renewable energy devices. Specifically, photovoltaic systems, building integrated photovoltaic collectors, hybrid photovoltaic/thermal systems, solar thermal collectors as well as other energy efficiency tools are analysed through different simulation approaches and suitable optimization procedures. Attention is also paid to specific case studies related to innovative combinations of renewable energy devices and innovative envelope materials in different building typologies and weather zones. In some papers, solar energy is exploited for space heating and cooling purposes, while in other articles renewables or other energy tools are studied to achieve comfort targets, low grid dependencies, smart building/communities, and mainly the zero energy building goal.