AMEBA is an Italian acronym which stands for “alta moderazione e basso arricchimento” (high moderation and low enrichment). The AMEBA reactor is nothing more than a PWR which possesses very unusual values of both volumetric ratio moderator/fuel and U-235 enrichment of UO2. The possibility is shown of the technical realisation of a nuclear power plant equipped with an AMEBA PWR reactor. Among the most enticing properties of AMEBA are the following: self-shut-down in any abnormal condition, elimination of all need for control rods and boric acid dissolution in the water, absolute impossibility of reaching values of reactivity greater than a fraction of a dollar, intrinsic subcriticality, attaining to several dollars, in non-operative condition when the water is at ambient temperature, normal operation with a very small-sized pressurizer, self-start-up.