Abstract The use of biomass derived pyrolysis oils, bio crude oil (BCO), in diesel engine requires deep modifications to the engine, such as the adoption of dual fuel systems and pilot injection: BCO/diesel emulsions are expected to significantly reduce the need for these adaptations. This paper describe the effects of various BCO/diesel emulsions on the injection systems of different diesel engines. Materials used for injectors’ nozzles and needles are investigated and compared. The issue of the erosion and/or corrosion of the injector nozzle is examined, and dedicated tests have been carried out. The experimental results suggested that corrosion accelerated by the high velocity turbulent flow in the spray channels is the dominant factor. A stainless steel nozzle has been built and successfully tested. Long term validation is however still needed.