China has built the world’s largest power transmission infrastructure by consuming massive volumes of greenhouse gas- (GHG-) intensive products such as steel. A quantitative analysis of the carbon implications of expanding the transmission infrastructure would shed light on the trade-offs among three connected dimensions of sustainable development, namely, climate change mitigation, energy access and infrastructure development. By collecting a high-resolution inventory, we developed an assessment framework of, and analysed, the GHG emissions caused by China’s power transmission infrastructure construction during 1990–2017. We show that cumulative embodied GHG emissions have dramatically increased by more than 7.3 times those in 1990, reaching 0.89 GtCO2-equivalent in 2017. Over the same period, the gaps between the well-developed eastern and less-developed western regions in China have gradually narrowed. Voltage class, transmission-line length and terrain were important factors that influenced embodied GHG emissions. We discuss measures for the mitigation of GHG emissions from power transmission development that can inform global low-carbon infrastructure transitions. Expanding energy infrastructure has been vital to China’s development plans, but has had negative consequences. This study finds that in 2017 the level of embodied greenhouse gas emissions from the expansion of China’s power transmission infrastructure increased by more than 7.3 times that in 1990.