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Valorisation of phenols to coumarins through one-pot palladium-catalysed double C–H functionalizations

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 2022 Italy Publisher:Royal Society of Chemistry (RSC)Journal:Green Chemistry, volume 24, pages 9,094-9,100 (issn: 1463-9262, eissn: 1463-9270,

Authors: Giulia Brufani; Federica Valentini; Flavio Sabatelli; Benedetta Di Erasmo; Anastasiia M. Afanasenko; Chao-Jun Li; Luigi Vaccaro;

doi: 10.1039/d2gc03579k

handle: 11391/1535314

Valorisation of phenols to coumarins through one-pot palladium-catalysed double C–H functionalizations

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Abstract

Herein a one-pot double C–H functionalization for constructing C8-alkyl substituted coumarins from phenols is reported. For the first time Pd/C as heterogenous catalyst was used to enable the synthesis of structurally divers coumarins.

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Italy

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University of Perugia
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Centre in Green Chemistry and Catalysis
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