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Green Chemistry

Article . 2023 . Peer-reviewed

License: Royal Society of Chemistry Licence to Publish

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Metal-free construction of aminated isoquinoline frameworks from 2-(2-oxo-2-arylethyl) benzonitrile in an aqueous medium

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 2023Publisher:Royal Society of Chemistry (RSC)Journal:Green Chemistry, volume 25, pages 167-171 (issn: 1463-9262, eissn: 1463-9270,

Authors: Himanshi Sharma; Manoj Kumar; Aaftaab Sethi; null Poonam; Brijesh Rathi;

doi: 10.1039/d2gc04044a

Metal-free construction of aminated isoquinoline frameworks from 2-(2-oxo-2-arylethyl) benzonitrile in an aqueous medium

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Abstract

Herein, we report a metal/additive-free protocol for the activation of nitrile towards nucleophilic addition and subsequent annulation under an aqueous medium for the first time.

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University of Delhi
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engineering and technology

electrical engineering, electronic engineering, information engineering

Fields of Science

engineering and technology

electrical engineering, electronic engineering, information engineering

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Energy Research