A method in experimental studies and industrial-polygon particular conditions justifying the choice of a rational design of an explosive charge. The comparative results of the evaluation of the stress wave’s amplitudes studies and the character of crushing hard media from the explosion of the charge explosives-variable and constant cross section. The dependences of the particle size distribution of various designs explosive charges destroyed by the explosion are constructed. In industrial conditions, the rationale for the explosive boreholes location according to the massif structure. Adjusted boreholes location grid on rational parameters blasting unit, determined using a novel method of breaking rock complex structure. A new design of a combined borehole charge of variable cross section has been proposed. Industrial tests performed and evaluation of the effectiveness of the proposed method blasting locally fractured rocks and ore deposits on non-metallic minerals. Recommendations on their use are given.