The definition of overall district heating network performance indicators is under-investigated in the literature. This study reviews existing methods of performance estimation and develops a convenient methodology for an array of district heating networks applied to a Danish case study. Performances of the networks with state-of-art pipe transmission coefficients are compared to older traditional pipes using an effective average approach. The reported efficiencies and analysis of contributing factors show, that a single parameter is not sufficient to compare large-scale district heating systems and a multiparametric analysis must be employed. The effective average total heat transmission coefficient is evaluated based on the Technical Evaluation Factor and a multivariate regression is performed on typical sets of network parameters: pipe type, pipe series, pipe age, and operational temperature. The developed methodology is applied to testing an array of geographically independent district heating networks, pointing to possible performance bottlenecks, and discussing potential remedies.