Abstract Indonesia has an abundance of various types of agricultural products. One of the abundance of agricultural products in Indonesia is cassava, but the skin is rarely used, so it can be a source of waste. Cassava peels can be used as a source of bioenergy in the form of biogas. This research was conducted by mixing the ratio of domestic waste mixing IPAL Cemara PDAM Tirtanadi and water by including cassava peels. In the slurry, cassava peels added about 8-9 % This study aims to determine the amount of biogas produced from bioreactors with and without silica gel as media. The ratio of domestic waste from IPAL Cemara PDAM Tirtanadi and water 1: 0, 1: 0.5, 1: 0.4 1: 0.3. The retention time during 23 days. The parameters tested from this study were COD, TSS, and VS. From the results of the research, it was found biogas from bioreactor ratio of 1: 0. In the bioreactor with silica gel media biogas was found on the 19th day with a pressure of 499.8 Pa, however in bioreactor without silica gel media, biogas was found at 294 Pa.