Abstract Thermal piping insulation of implants is crucial for heat delivery, production, collection, or storage at high temperature values. It is currently obtained by enveloping low thermal conductivity materials such as rockwool, fiberglass, polyurethane, polystyrene, and aerogel. However, better performances can be reached by adopting vacuum technology. In this case, conductive losses are annihilated, and the radiative heat transfer mechanism represents the only loss mechanism. Here, we compare a high vacuum-based novel solution and the traditional insulation for heat delivery applications. We propose a high vacuum- based solution consisting of an evacuated gap that surrounds the hot pipe coated by a thin aluminium foil. Experimental results using this novel solution show a fivefold reduction of the thermal radiation losses compared to the traditional solutions when in the temperature range between 100 °C and 250 °C.