Abstract The quasi-static compression, three-point bending and low-speed impact behavior of E690 high-strength steel lattice corrugated sandwich panels after corrosion in a marine environment were simulated by a non-linear finite element method. The uniform corrosion model was used to calculate the effects of different levels and duration of corrosion on the bearing capacity and energy absorption of an E690 panel. The results show that the corrosion of the outer panel has the least influence on the decrease of the mechanical properties; the structure’s mechanical properties are greatly reduced by the inner panel and core corrosion, and a new deformation pattern could be observed. Considering the influence of corrosion duration, the mechanical performance ranges from bad to good: outer+inner > inner > outer. Furthermore, the difference becomes more obvious with longer corrosion times, indicating that necessary corrosion protection measures should be taken to protect the panel from corrosion in marine environment, especially for the internal part of the panel.