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Contribution of secondary particles to the dose in 12C radiotherapy and other heavy ion beams

doi: 10.1093/rpd/ncm133
pmid: 17504750
The results of experimental studies performed in a radiotherapy (12)C ion beam with a nominal energy of 500 MeV/amu and in (16)O and (56)Fe ion beams with a nominal energy of 1 GeV/amu have been described. Linear energy transfer (LET) spectra have been established by means of an LET spectrometer based on a chemically etched track detector, and the measured results were also compared with theoretical calculations obtained using the program Stopping and Range of Ions in Matter (SRIM). It was observed that with increasing depth in a beam, the LET spectra are shifted towards higher values of LET; one can also observe an important widening of the spectra along the range, as well as an increasing amount of nuclear reaction products and/or of fragments in the spectra. The relative contribution of these secondary particles to the total absorbed dose was assessed.
- Joint Institute for Nuclear Research Russian Federation
- Institute of Nuclear Physics Kazakhstan
- Joint Institute for Nuclear Research Russian Federation
- Czech Technical University in Prague Czech Republic
- Institute of Nuclear Physics Kazakhstan
Neutrons, Radiotherapy Planning, Computer-Assisted, Reproducibility of Results, Heavy Ion Radiotherapy, Radiotherapy Dosage, Models, Biological, Sensitivity and Specificity, Radiation Protection, Radiation Monitoring, Humans, Computer Simulation, Linear Energy Transfer, Carbon Radioisotopes
Neutrons, Radiotherapy Planning, Computer-Assisted, Reproducibility of Results, Heavy Ion Radiotherapy, Radiotherapy Dosage, Models, Biological, Sensitivity and Specificity, Radiation Protection, Radiation Monitoring, Humans, Computer Simulation, Linear Energy Transfer, Carbon Radioisotopes
citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).3 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Average influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Average impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Average
