This paper analyzes the general issues of sectionalizing 110- and 220-kV distribution grids, including by current limiting. The results of calculations of transients in the event of various disturbances in the distribution network, taking into account the operation of emergency control devices, are presented. The results of comparative analysis of sectionalized and desectionalized distribution grids are presented. The authors hereof propose introducing a load increment safety factor to quantify how sectionalization or desectionalization could affect grid reliability. The paper further substantiates the need for accounting excess disturbances in sectionalized grids to design and implement measures to minimize accident-related losses. It analyzes the effectiveness of applying automatic load transfer (ALT) and draws recommendations on how to implement it.