This paper summarizes the technical endeavors undertaken by the Task Force (TF) on Cyber-Physical Interdependence for Power System Operation and Control. The TF was established to investigate the cyber-physical interdependence of critical power system elements and their influence on the operation and control of energy systems. State-of-the-art analysis techniques, including co-simulation and digital twin technologies, are employed to address various layers of interdependence between cyber and physical systems, facilitating the identification of potential threats and vulnerabilities. The paper examines prospective trajectories for resilient cyber-physical systems and outlines the educational and workforce training imperatives for addressing cybersecurity threats in contemporary power systems. Furthermore, concluding remarks and future recommendations are provided to mitigate the inherent vulnerabilities within the extensively interoperable grid infrastructure.