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Chemical and Pharmaceutical Bulletin
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Solubility of Pioglitazone Hydrochloride in Binary Mixtures of Polyethylene Glycol 400 with Ethanol, Propylene Glycol, N-Methyl-2-pyrrolidone, and Water at 25 .DEG.C

descriptionPublicationkeyboard_double_arrow_right Article , Journal 01 Jan 2010Publisher:Pharmaceutical Society of JapanJournal:Chemical and Pharmaceutical Bulletin, volume 58, pages 1,132-1,135 (issn: 0009-2363, eissn: 1347-5223, Copyright policy )
Authors: Abolghasem Jouyban; Shahla Soltanpour;

doi: 10.1248/cpb.58.1132

pmid: 20823589

Solubility of Pioglitazone Hydrochloride in Binary Mixtures of Polyethylene Glycol 400 with Ethanol, Propylene Glycol, N-Methyl-2-pyrrolidone, and Water at 25 .DEG.C

Abstract

The solubility of pioglitazone hydrochloride in binary mixtures of polyethylene glycol 400 with ethanol, N-methyl-2-pyrrolidone, propylene glycol, and water at 25 degrees C are reported. The generated data are fitted to the Jouyban-Acree model and the mean relative deviations are 2.6%, 1.5%, 5.8%, and 7.4%, respectively for ethanol, N-methyl-2-pyrrolidone, propylene glycol, and water.

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Keywords

Ethanol, Pioglitazone, Temperature, Water, Propylene Glycol, Pyrrolidinones, Polyethylene Glycols, Solubility, Hypoglycemic Agents, Thiazolidinediones

  • BIP!
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    citations
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 17
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Average
    influence
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    		 Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
17
Average
Top 10%
Top 10%
gold
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