The traditional power grid is inadequate to overcome modern day challenges. As the modern era demands the traditional power grid to be more reliable, resilient, and cost-effective, the concept of smart grid evolves and various methods have been developed to overcome these demands which make the smart grid superior over the traditional power grid. One of the essential components of the smart grid, home energy management system (HEMS) enhances the energy efficiency of electricity infrastructure in a residential area. In this aspect, we propose an efficient home energy management controller (EHEMC) based on genetic harmony search algorithm (GHSA) to reduce electricity expense, peak to average ratio (PAR), and maximize user comfort. We consider EHEMC for a single home and multiple homes with real-time electricity pricing (RTEP) and critical peak pricing (CPP) tariffs. In particular, for multiple homes, we classify modes of operation for the appliances according to their energy consumption with varying operation time slots. The constrained optimization problem is solved using heuristic algorithms: wind-driven optimization (WDO), harmony search algorithm (HSA), genetic algorithm (GA), and proposed algorithm GHSA. The proposed algorithm GHSA shows higher search efficiency and dynamic capability to attain optimal solutions as compared to existing algorithms. Simulation results also show that the proposed algorithm GHSA outperforms the existing algorithms in terms of reduction in electricity cost, PAR, and maximize user comfort.