Energy-saving and energy-recovery strategies represent key factors to achieve operational cost reductions within rail systems’ management tasks. However, in altering service features, they also affect passenger satisfaction. This paper investigates the effect of implementing such measures in the case of rolling stock unavailability. Numerous operational scenarios were explored by analysing different planned headway and rolling stock configurations. The scenarios were simulated with and without the adoption of Energy-Saving Strategies (ESS), both in ordinary and in disruption conditions. Our results show that, in ordinary conditions, the optimal scenarios are those that minimise the planned headway. By contrast, in disrupted conditions, due to greater passenger inconvenience, the use of a time-optimal condition is preferable if a real-time adjustment of ESS is not feasible. However, if the ESS can be updated in real-time, use of ESS is preferable only if the adopted headway is the smallest of those associated with the rolling stock scheme considered.