With renewable power sources and new topology structures being widely introduced into the power system, the current local information-based power generation-side protection cannot fully guarantee the protection performance and the safety coordination with the power grid. This paper proposes an improved hierarchical protection system on the power generation-side. The proposed system takes advantage of the fusion of multi-information provided by the system, station and local layers. The system layer provides the information such as system voltage control and power regulation demand, so that the generation-side protection and control system can adapt to the system operation mode and power regulation demand. The station layer realizes the coordination of the protection principle and action strategy among the related units through information interaction with the power grid, the automatic control system and the local layer protection. The local layer introduces the condition monitoring information and more abundant protection information to enhance the protection performance and master the generation units’ safety condition. To illustrate the hierarchical protection system construction method and actual application mode, the multi-information fusion-based comprehensive local layer protection method and the multi-generators information fusion-based hierarchical protection method are taken as examples. Case analysis shows that the proposed methods can reflect more slight internal fault forms and can adaptively determine the protection action characteristic and tripping strategy according to the system operating conditions and other generators’ fault conditions, which effectively improve the protection sensitivity and coordination capability. To provide reference and inspiration for follow-up research, the hierarchical protection system construction mode, communication technology and research approaches of new protection methods are further pointed out.