A three-phase multi-level multi-input power converter topology is presented for grid-connected applications. It encompasses a three-phase transformer that is operated on the primary side in an open-end winding configuration. Thus, the primary winding is supplied on one side by a three-phase N-level neutral point clamped inverter and, on the other side, by an auxiliary two-level inverter. A key feature of the proposed approach is that the N-level inverter is able to perform independent management of N − 1 input power sources, thus avoiding the need for additional dc/dc power converters in hybrid multi-source systems. Moreover, it can manage an energy storage system connected to the dc-bus of the two-level inverter. The N-level inverter operates at a low switching frequency and can be equipped with very low on-state voltage drop Insulated-Gate Bipolar Transistor (IGBT) devices, while the auxiliary inverter is instead operated at low voltage according to a conventional high-frequency two-level Pulse Width Modulation (PWM) technique and can be equipped with very low on-state resistance Metal-Oxide-Semiconductor Field-Effect Transistor (MOSFET) devices. Simulations and experimental results confirm the effectiveness of the proposed approach and its good performance in terms of grid current harmonic content and overall efficiency.