Remaining useful life (RUL) is a crucial assessment indicator to evaluate battery efficiency, robustness, and accuracy by determining battery failure occurrence in electric vehicle (EV) applications. RUL prediction is necessary for timely maintenance and replacement of the battery in EVs. This paper proposes an artificial neural network (ANN) technique to predict the RUL of lithium-ion batteries under various training datasets. A multi-channel input (MCI) profile is implemented and compared with single-channel input (SCI) or single input (SI) with diverse datasets. A NASA battery dataset is utilized and systematic sampling is implemented to extract 10 sample values of voltage, current, and temperature at equal intervals from each charging cycle to reconstitute the input training profile. The experimental results demonstrate that MCI profile-based RUL prediction is highly accurate compared to SCI profile under diverse datasets. It is reported that RMSE for the proposed MCI profile-based ANN technique is 0.0819 compared to 0.5130 with SCI profile for the B0005 battery dataset. Moreover, RMSE is higher when the proposed model is trained with two datasets and one dataset, respectively. Additionally, the importance of capacity regeneration phenomena in batteries B0006 and B0018 to predict battery RUL is investigated. The results demonstrate that RMSE for the testing battery dataset B0005 is 3.7092, 3.9373 when trained with B0006, B0018, respectively, while it is 3.3678 when trained with B0007 due to the effect of capacity regeneration in B0006 and B0018 battery datasets.