This study evaluates the viability of n-octanol as an alternative fuel in a direct-injection diesel engine, aiming to enhance sustainability and efficiency. Experiments fueled by different blends of n-octanol with pure diesel were conducted to analyze their impacts on engine performance and emissions. The methodology involved testing each blend in a single-cylinder engine, measuring engine performance parameters such as brake torque and brake power under full-load conditions across a range of engine speeds. Comparative assessments of performance and emission characteristics at a constant engine speed were also conducted with varying loads. The results indicated that while n-octanol blends consistently improved brake thermal efficiency, they also increased brake-specific fuel consumption due to the lower energy content of n-octanol. Consequently, while all n-octanol blends reduced nitrogen oxide emissions compared to pure diesel, they also significantly decreased carbon monoxide, hydrocarbons, and smoke opacity, presenting a comprehensive reduction in harmful emissions. However, the benefits came with complex trade-offs: notably, higher concentrations of n-octanol led to a relative increase in nitrogen oxide emissions as the n-octanol ratio increased. The study concludes that n-octanol significantly improves engine efficiency and reduces diesel dependence, but optimizing the blend ratio is crucial to balance performance improvements with comprehensive emission reductions.