This study describes the optimization of Distribution Network Structure (DNS) by altering sectionalizing and tie-switches with Reactive Power Injections (RPI) through optimal nodes under three load variations considering five different cases in Electric Distribution Networks (EDNs) to reduce Energy Loss (ELoss), thereby achieving Economic Benefit (EB), which is the first step process. This approach yields EBs only to some extent. To achieve a greater reduction in ELoss, enhancing bus voltage profile and to achieve additional EBs, this study examines the incorporation of Renewable Energy Generations (IREGs) into the optimal EDNs with reactive power support. The optimal energy has been purchased from the Independent Power Producers (IPPs). Besides, the Levy Flight Mechanism (LFM) integrated Seagull Optimization Algorithm (SOA) has been applied to solve the Economic Based Objective Function. The effectiveness of the developed methodology has been validated using IEEE 33-bus and a real 74-bus Myanmar EDN. The reductions in ELoss achieved by LFM-SOA have been compared with those of other existing methods in the literature for all the cases. The results reveals that the developed methodology efficiently achieves more EBs ($) for all the cases by optimizing DNSA with and without RPIs and IREGs.