Multimodal transport terminals are the elements of transport systems that ensure the interaction of enterprises of various modes of transport. The effective functioning of transport terminals significantly affects the efficiency of the material flow servicing in a supply chain and the sustainability of the whole transport system. The paper proposes an approach to determine the optimal parameters of production resources in multimodal transport terminals, based on numerical computer simulations of technological operations in a transport terminal for the given parameters of incoming and outgoing material flows. The practical use of the proposed approach is shown on the example of the Amur Harbor cargo area of the Dnipro River Port.