Ensuring territorial safety is one of the state’s main tasks, and the public administration plays a primary role in fulfilling it. The safety and sustainability of a territory is ensured by, inter alia, safety planning, including spatial planning. Spatial planning contains safety requirements for population protection. The requirements for ensuring the safety of the population included in the spatial plan vary significantly between countries. The existing population protection requirements contained in the spatial plan have been unsatisfactory for a long time. The main issue is that they are out of date and difficult to apply. The article presents a new proposed method for determining requirements for the protection of the population, which is based on evaluating the risks in the cities and territory. The specific population protection requirements are determined based on the resulting risks and their scaling. The requirements are classified as general when the territory is not faced with external risks or specific when there are such risks. The method is applied to the conditions of the Czech Republic. In terms of national standard specifics, there are requirements in areas of public infrastructure, public utility buildings, and public benefit measures. The method for determining population protection requirements can be considered applicable in a general form by various countries if the national standards specifics or other aspects are taken into account.