Natural dyes have become an interesting subject of study because of their superior ecological properties in comparison to their synthetic counterparts. This explains the great amount of research developed in this regard, especially when the dye used was derived from a natural product’s waste. This research aims to evaluate the affinity of the dye extracted from date palm fibrillium to a multifiber fabric. This choice was made to investigate a comparison of the dyeability of many kinds of textile fibers with the obtained colorant from the date palm fibrillium. It was shown that the different types of fibers were well-dyed. The darkest dyes were obtained especially by using wool and nylon fabrics. In view of these results, wool and nylon fibers were selected for developing a dyeing investigation. The effect of the most important operational conditions such as temperature, pH, and dyeing time on the dyeing quality results has been investigated. Color yield (K/S) and CIELab values (L*, a*, b*, C*, h*) were used to evaluate the dyeing properties. The utilization of durable chemicals and bio-mordants both pre and post-dyeing resulted not only in new dyes but also in improved speed rates.