In this study, a fuzzy proportional integral derivative controller (FPID) was adjusted using the differential evolution (DE) method to enhance the automated generation control (AGC) of a three-zone reheat-type power system. The objective function used in this study was an integral of the time-weighted absolute error (ITAE). In the optimization, the gain control parameters of the proportional integral (PI), the integral (I), and FPID were optimized and compared to improve the limitations drawn by the controller over a few parameters. To demonstrate that FPID controllers with IPFC produce better and more accurate optimization results than integral and PI controllers optimized by DE, the interline power flow control (IPFC) of a flexible AC transmission system (FACTS) device with suitable connections and control parameter optimization was used. Also, the particle swarm optimization (PSO) PID with IPFC was compared with the proposed DEFPID + IPFC, and better results were achieved by using the DE technique. Similarly, to demonstrate the suggested technology’s strong control capacity, random load changes were applied to the system in various conditions, and it was demonstrated that the suggested control unit easily tolerated random load perturbations and returned the system to a stable functioning state.