The primary objective of this paper is to analyse households’ adaptation measures to the impacts of repeated extreme weather events, specifically floods, which belong amongst the most serious manifestation of ongoing climate change in Europe. The case study focuses on a rural area in the north-east part of the Czech Republic, in the catchment basin of the Bečva River. A total of 605 households were addressed within the framework of the questionnaire survey. On the basis of the conducted research, we determined that the total amount of adaptation measures adopted by those dwelling in residential homes within the investigated catchment area was relatively low. In contrast, however, one of the most important adaptation measures—house elevation—was applied by 46.94% of the houses (up to 1 m) and by 21.16% houses (elevated more than 1 m) respectively. We also found that the amount and scope of adaptation measures realized by households were influenced by certain socio-demographic factors of the inhabitants. The most statistically significant factors included households with more residents or families with more children living in the household, as well as those with a higher level of education. Flood experience, the level of damage, and individual flood risk perception also played an important role.