<div class="section abstract"><div class="htmlview paragraph">The upcoming regulations to achieve zero-emission passenger transport present challenges for designing new ferry powertrains. The proposed work investigates the feasibility of using a Proton Exchange Membrane Fuel Cell (PEMFC) power system to power a long-haul ferry. The paper describes the zero-order cell model as well as the method for estimating cell degradation. The stack modeling, heat balance equations, and auxiliary modeling are also presented. The proposed model enables the simulation of the fuel cell under different operating conditions and includes the use of air or oxygen as an oxidizer. A thermal management strategy for the overall PEMFC system is also proposed. The model was calibrated on the characteristic curves of the PEMFC Ballard FCvelocity™ HD6 (150 kW) and validated by reproducing experimental results. Then, a real load profile of a ferry, as well as the proposed powertrain is considered as case study. The presented results are related to a single daily mission and its deterioration throughout the set mission cycle is finally presented.</div></div>