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SUBSTITUED OXAZOLES AND THIAZOLES AS HPPAR ALPHA AGONISTS

Authors: GLAXO GROUP LTD; SIERRA MICHAEL LAWRENCE;

SUBSTITUED OXAZOLES AND THIAZOLES AS HPPAR ALPHA AGONISTS

Abstract

Compounds of formula (I) and pharmaceutically acceptable salts, solvates and hydrolysable esters thereof wherein X is O or S; X is O or S; X is S or O; R and R are independently H, methyl, or halogen; R and R are independently H or C1-3 alkyl or R and R may, together with the carbon atom to which they are bonded, form a 3-5 membered cycloalkyl ring; R and R are independently H, C1-3 alkyl, or allyl; each R is independently halogen, C1-6 straight or branched alkyl, or CF3; and y is 0, 1, 2, 3, 4 or 5 act as hPPAR alpha agonists.

Countries
France, United Kingdom
Keywords

IPC: C07D277/24, IPC: A61P9/10, IPC: A61P3/06, IPC: A61K31/426

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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
Related to Research communities
Energy Research