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Abstract The effects of ethanol and pentobarbital on flurothyl seizure susceptibility were studied in two lines of mice that were derived by selective breeding with respect to ethanol sleep time. Short-sleep mice (SS) were more susceptible than long-sleep mice (LS) to flurothyl-induced myoclonus, but there was no line difference in susceptibility to clonus. Low doses of ethanol or pentobarbital increased seizure latencies in both populations, and there was no difference between the lines in the effect of these drugs. The lack of difference in response to ethanol in the two populations indicates that the genetic mechanisms which determine sensitivity to ethanol's anticonvulsant action are not identical with those which determine sensitivity to its depressant action.

The effect of delta 9-tetrahydrocannabinol (delta 9-THC) and alcohol, singly and in combination, on divided attention performance was investigated in cannabis users and non-users who were matched for alcohol use. Both cannabis and alcohol produced decrements in central and peripheral signal detections. Drug and alcohol effects were greater for signal presentations in the periphery. Cannabis users were less impaired in peripheral signal detection than non-users while intoxicated by cannabis and/or alcohol. These findings suggest the development of tolerance and cross-tolerance in regular cannabis users and/or the ability to compensate for intoxication effects.

This research examines the economic implications of different designs for a national low carbon fuel standard (NLCFS) for the road transportation sector. A NLCFS based on the average Carbon Intensity (CI) of all fuels sold generates an incentive for fuel suppliers to reduce the measured CI of their fuels. The economic impacts are determined by the availability of low carbon fuels, estimates of which can vary widely. Also important are the compliance path, reference level CI, and the design of the credit system, particularly the opportunities for trading and banking. To quantitatively examine the implications of a NLCFS, we created the Transportation Regulation and Credit Trading (TRACT) Model. With TRACT, we model a NLCFS credit trading system among profit maximizing fuel suppliers for light- and heavy-duty vehicle fuel use for the United States from 2012 to 2030. We find that credit trading across gasoline and diesel fuel markets can lower the average costs of carbon reductions by an insignificant amount to 98% depending on forecasts of biofuel supplies and carbon intensities. Adding banking of credits on top of trading can further lower the average cost of carbon reductions by 5%–9% and greatly reduce year-to-year fluctuations in credit prices.

The division of return stroke current among the arresters and groundings of two unenergized test distribution lines, one horizontally configured and the other vertically configured, was studied at the International Center for Lightning Research and Testing in Florida. The division of return stroke currents for the vertically configured line was initially similar to the division on the horizontally configured line: at the time the return stroke current reached peak value (after one microsecond, or so) the two closest arresters/grounds on both lines passed about 90% of the total current. However, the time during which the return stroke current flowed primarily through the closest arresters to the neutral conductor was significantly shorter on the vertically configured line. On that line, the arrester current was about equally divided among all four arresters after several tens of microseconds. The arrester current division as a function of time measured on the vertical line was successfully modeled using the published VI-characteristic, while the division on the horizontal line after some tens of microseconds was only successfully modeled if the residual voltage of the two arresters closest to the current injection point was reduced by 20%. Based on the triggered lightning current division observed on our line, the minimum energy absorbed in each of the two arresters closest to the strike point during a typical natural first stroke is estimated to be 40 kJ.

Five different hybrid solar power systems using silicon solar cells to produce thermal and electric power are modeled and compared with a hybrid system using a GaAs cell. Among the indices determined are capital cost per unit electric power plus mechanical power, annual cost per unit electric energy, and annual cost per unit electric plus mechanical work. Current costs are taken to be $35,000/sq m for GaAs cells with an efficiency of 15% and $1000/sq m for Si cells with an efficiency of 10%. It is shown that hybrid systems can be competitive with existing methods of practical energy conversion. Limiting values for annual costs of Si and GaAs cells are calculated to be 10.3 cents/kWh and 6.8 cents/kWh, respectively. Results for both systems indicate that for a given flow rate there is an optimal operating condition for minimum cost photovoltaic output. For Si cell costs of $50/sq m optimal performance can be achieved at concentrations of about 10; for GaAs cells costing 1000/sq m, optimal performance can be obtained at concentrations of around 100. High concentration hybrid systems offer a distinct cost advantage over flat systems.

The paper describes formation and spreading of dense shelf waters in the Adriatic Sea (North Adriatic Dense Water, NAdDW) during the winter of 2012 as a consequence of an intense and long cold air outbreak of northeasterly Bora winds. As a result, during February 2012 northern Adriatic Sea water temperature dropped to about 6 degrees C and density exceeded 1030 kg/m(3), most likely the maximum value since 1929. NAdDW dynamics has been investigated by means of a 3-D ocean-wave coupled model running on a high resolution and eddy-permitting grid. The numerical experiments have relied on the Coupled-Ocean-Atmosphere-Wave-Sediment-Transport (COAWST) system forced one-way with atmospheric forcings provided by the model COSMO-17. A suite of observational data has been used to characterize the Bora event and evaluate numerical model performance. At sub-basin scales, the newly formed waters flowing southerly have produced a water renewal of the northern Adriatic, as more than 50% of water volumes have left the basin. Dense waters volume transports, evaluated through different Adriatic cross-sections, have been modulated by tides (damped for the densest water masses) and reached about 1 Sv. The contribution of wave-induced forcings has been quantified and examined, indicating that these represent a major driving mechanism during NAdDW production and spreading phases. This work provides evidence that NAdDW is spread accordingly with two different mechanisms: at early stages of its formation, the wind-driven ocean circulation pushes newly formed waters to leave the northern basin with relatively high speeds (about 0.30 m/s). Later on, remaining NAdDW leaks slowly out (0.09 m/s as average) from the production site. Residence times of dense waters in the north, middle, and south Adriatic Sea are also documented. (C) 2014 Elsevier Ltd. All rights reserved.