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Research data keyboard_double_arrow_right Dataset 2021Publisher:Zenodo Funded by:EC | HELIXEC| HELIXAuthors:Thiery, Wim;
Lange, Stefan; Rogelj, Joeri; Schleussner, Carl-Friedrich; +33 AuthorsThiery, Wim
Thiery, Wim in OpenAIREThiery, Wim;
Lange, Stefan; Rogelj, Joeri; Schleussner, Carl-Friedrich; Gudmundsson, Lukas; Seneviratne, Sonia I.; Andrijevic, Marina; Frieler, Katja; Emanuel, Kerry; Geiger, Tobias; Bresch, David N.; Zhao, Fang; Willner, Sven N.; Büchner, Matthias; Volkholz, Jan; Bauer, Nico; Chang, Jinfeng; Ciais, Philippe; Dury, Marie; François, Louis; Grillakis, Manolis; Gosling, Simon N.; Hanasaki, Naota; Hickler, Thomas; Huber, Veronika; Ito, Akihiko; Jägermeyr, Jonas; Khabarov, Nikolay; Koutroulis, Aristeidis; Liu, Wenfeng; Lutz, Wolfgang; Mengel, Matthias; Müller, Christoph; Ostberg, Sebastian; Reyer, Christopher P. O.; Stacke, Tobias; Wada, Yoshihide;Thiery, Wim
Thiery, Wim in OpenAIREThis data set contains the essential files used as input for the analysis, intermediate files produced during the analysis, and the key output fields. The code of the analysis is available here: https://github.com/VUB-HYDR/2021_Thiery_etal_Science Input fields: - isimip.zip: Postprocessed ISIMIP2b simulation output. This data set is very similar to the data presented in Lange et al. (2020 Earth's Future) but includes selected additional impact models and scenarios (notably RCP8.5). This data set also includes the gridded population data. - GMT_50pc_manualoutput_4pathways.xlsx: Global mean temperature anomaly trajectories from the IPCC SR15 - wcde_data.xlsx: postprocessed cohort size data originally obtained from the Wittgenstein Centre Human Capital Data Explorer. - WPP2019_MORT_F16_1_LIFE_EXPECTANCY_BY_AGE_BOTH_SEXES.xlsx: Postprocessed life expectancy data originally obtained from the UNited Nations World Population Programme Intermediate files *only use if you're interested in reproducing the results*: - workspaces.zip: Postprocessed ISIMIP2b simulation output. These matlab workspaces contain data on land area annually exposed to extreme events which is stored in a format designed to speed up the analysis. - mw_isimip.mat: ISIMIP2 simulations metadata (e.g. model, gcm and rcp name per simulation) - mw_countries.mat: information on the countries used in the analysis (e.g. border polygon coordinates) - mw_exposure.mat: age-dependent exposure computed from the ISIMIP and population data - mw_exposure_pic.mat: pre-industrial control age-dependent exposure computed from the ISIMIP and population data - mw_exposure_pic_coldwaves.mat: pre-industrial control age-dependent exposure to coldwaves computed from the ISIMIP and population data Output of the analysis: - mw_output.mat: Matlab workspace containing all variables produced during the analysis presented in thepaper. Use this file if you wish to look up certain numbers or want to use the study results for further analysis.
add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
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You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.5281/zenodo.5497632&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu0 citations 0 popularity Average influence Average impulse Average Powered by BIP!
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You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.euResearch data keyboard_double_arrow_right Dataset 2019 United KingdomPublisher:Zenodo Authors:Smith, Christopher;
Smith, Christopher
Smith, Christopher in OpenAIREForster, Piers;
Forster, Piers
Forster, Piers in OpenAIREAllen, Myles;
Allen, Myles
Allen, Myles in OpenAIREFuglestvedt, Jan;
+3 AuthorsFuglestvedt, Jan
Fuglestvedt, Jan in OpenAIRESmith, Christopher;
Smith, Christopher
Smith, Christopher in OpenAIREForster, Piers;
Forster, Piers
Forster, Piers in OpenAIREAllen, Myles;
Allen, Myles
Allen, Myles in OpenAIREFuglestvedt, Jan;
Fuglestvedt, Jan
Fuglestvedt, Jan in OpenAIREMillar, Richard;
Millar, Richard
Millar, Richard in OpenAIRERogelj, Joeri;
Rogelj, Joeri
Rogelj, Joeri in OpenAIREZickfeld, Kirsten;
Zickfeld, Kirsten
Zickfeld, Kirsten in OpenAIREhandle: 10044/1/65931
This package generates all of the model runs and plotting code for "Current infrastructure does not yet commit us to 1.5°C warming". See enclosed README file for dependencies and how to run.
ZENODO arrow_drop_down Imperial College London: SpiralDataset . 2019License: CC BYData sources: Bielefeld Academic Search Engine (BASE)add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.5281/zenodo.1565230&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu0 citations 0 popularity Average influence Average impulse Average Powered by BIP!
more_vert ZENODO arrow_drop_down Imperial College London: SpiralDataset . 2019License: CC BYData sources: Bielefeld Academic Search Engine (BASE)add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.5281/zenodo.1565230&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euResearch data keyboard_double_arrow_right Dataset 2021Publisher:Zenodo Authors:Pappis, Ioannis;
Pappis, Ioannis
Pappis, Ioannis in OpenAIRESridharan, Vignesh;
Sridharan, Vignesh
Sridharan, Vignesh in OpenAIREHowells, Mark;
Howells, Mark
Howells, Mark in OpenAIREMedarac, Hrvoje;
+4 AuthorsMedarac, Hrvoje
Medarac, Hrvoje in OpenAIREPappis, Ioannis;
Pappis, Ioannis
Pappis, Ioannis in OpenAIRESridharan, Vignesh;
Sridharan, Vignesh
Sridharan, Vignesh in OpenAIREHowells, Mark;
Howells, Mark
Howells, Mark in OpenAIREMedarac, Hrvoje;
Medarac, Hrvoje
Medarac, Hrvoje in OpenAIREKougias, Ioannis;
Kougias, Ioannis
Kougias, Ioannis in OpenAIRESánchez, G. Rocío;
Shivakumar, Abhishek;Sánchez, G. Rocío
Sánchez, G. Rocío in OpenAIREUsher, Will;
Usher, Will
Usher, Will in OpenAIREThis dataset underpins the study "Synergies and conflicts of energy development and water security in Africa". The study provides insights into energy supply and demand, power generation, investments and total system costs, water consumption and withdrawal as well as carbon dioxide emissions for the African continent. We developed a model to evaluate energy supply and water requirements to cover the energy needs of the African continent during the period 2015-2065. The model was developed using the open-source modeling system for long-term energy planning OSeMOSYS. The objective function is to minimise total energy system costs, rather than, for example, co-optimise the energy and water sectors. Other energy resources were also included in the model except for adding the water analysis, and the dataset was updated based on the latest available information. The OSeMOSYS model developed to conduct the study “Energy projections for African countries”, itself extended from the Electricity Model Base for Africa (TEMBA), was further extended, included exports for all fuels, water loss due to evaporation in hydropower plants and more scenarios examined. Furthermore, the latest available data on the energy system of Africa was also updated. The TEMBA model produces aggregate energy, and detailed power system results in each country in the African continent. The power sector results are also reported with power pool aggregation. The OSeMOSYS model and input data used to produce these results can be found at KTH-dESA/jrc_temba: TEMBA 2.1 (Version v2.1) [Data set]. Zenodo. http://doi.org/10.5281/zenodo.4889373 (Authors: Ioannis Pappis, Vignesh Sridharan, Will Usher, & Mark Howells. (2021). The initial study was funded by the Joint Research Centre of the European Commission (contract number C936531 - JRC/PTT/2018/C.7/0038/NC).
ZENODO arrow_drop_down Smithsonian figshareDataset . 2021License: CC BYData sources: Bielefeld Academic Search Engine (BASE)add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.5281/zenodo.3882052&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu1 citations 1 popularity Average influence Average impulse Average Powered by BIP!
visibility 80visibility views 80 download downloads 10 Powered bymore_vert ZENODO arrow_drop_down Smithsonian figshareDataset . 2021License: CC BYData sources: Bielefeld Academic Search Engine (BASE)add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.5281/zenodo.3882052&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article 2023 United KingdomPublisher:Informa UK Limited Authors:Richard Syms;
Richard Syms
Richard Syms in OpenAIRESimon D Taylor-Robinson;
Simon D Taylor-Robinson
Simon D Taylor-Robinson in OpenAIREGuglielmo Trovato;
Guglielmo Trovato
Guglielmo Trovato in OpenAIREIn the light of the COP27 Climate Change Conference, the concept of the circular economy has come to the fore with promotion of reuse and recycling of appliances and materials from electronics to clothes. This concept has not been widely taken up by healthcare systems. In this perspective article, we discuss the idea of the circular economy and how, by extension, the concept of "circular medicine" with optimised hospital and medical clinic waste recycling might be promoted in the context of better stewardship of resources in healthcare management.
Imperial College Lon... arrow_drop_down Imperial College London: SpiralArticle . 2023License: CC BYFull-Text: http://hdl.handle.net/10044/1/102987Data sources: Bielefeld Academic Search Engine (BASE)Risk Management and Healthcare PolicyArticle . 2023 . Peer-reviewedLicense: CC BYData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.2147/rmhp.s396667&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess RoutesGreen gold 0 citations 0 popularity Average influence Average impulse Average Powered by BIP!
visibility 1visibility views 1 download downloads 2 Powered bymore_vert Imperial College Lon... arrow_drop_down Imperial College London: SpiralArticle . 2023License: CC BYFull-Text: http://hdl.handle.net/10044/1/102987Data sources: Bielefeld Academic Search Engine (BASE)Risk Management and Healthcare PolicyArticle . 2023 . Peer-reviewedLicense: CC BYData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.2147/rmhp.s396667&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Journal 2018 United Kingdom, United KingdomPublisher:Springer Science and Business Media LLC Authors:A. Fantetti;
A. Fantetti
A. Fantetti in OpenAIREC. Gastaldi;
C. Gastaldi
C. Gastaldi in OpenAIRET.M. Berruti;
T.M. Berruti
T.M. Berruti in OpenAIREhandle: 10044/1/63384
This paper deals with the dynamic of blades with strip dampers. The purpose is 1) to present the results of the dynamic numerical calculation, 2) to demonstrate the need for the experimental data on the blade-strip contact to be used as input to the calculation, 3) to propose a new test rig design to obtain them and 4) to test the key components of the new test rig. The forced responses of two blades coupled by a strip damper are calculated at different excitation and centrifugal force values. The dependence of the numerical results on the contact parameter values is confirmed in this significant reference case. The design of a new test rig is then proposed: both the blade frequency response function and the contact hysteresis cycles at the blade-strip contact are measured. It is shown how contact parameters can then be derived from experimental data. The main novelty of the test rig here proposed is the strip loading system, which simulates the uniform pressure distribution provided by the centrifugal force in real operating conditions. This loading system is non-contact and uses compressed air. Classical loading systems which see dead weights directly connected to the strip are assessed and their expected inadequacy is confirmed. The compressed air system is tested by measuring the pressure produced between strip and blades: pressure is uniform across the contact patch, constant in time and its mean value corresponds to realistic pressure values actually experienced by strip dampers during service.
Hyper Article en Lig... arrow_drop_down Imperial College London: SpiralArticle . 2018License: CC BYFull-Text: http://hdl.handle.net/10044/1/63384Data sources: Bielefeld Academic Search Engine (BASE)add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1007/s40799-018-0248-z&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess RoutesGreen hybrid 14 citations 14 popularity Top 10% influence Average impulse Top 10% Powered by BIP!
visibility 4visibility views 4 download downloads 28 Powered bymore_vert Hyper Article en Lig... arrow_drop_down Imperial College London: SpiralArticle . 2018License: CC BYFull-Text: http://hdl.handle.net/10044/1/63384Data sources: Bielefeld Academic Search Engine (BASE)add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1007/s40799-018-0248-z&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article 2022 United KingdomPublisher:Elsevier BV Authors: D. Petrovskyy;C. Jacquemyn;
C. Jacquemyn
C. Jacquemyn in OpenAIRES. Geiger;
S. Geiger
S. Geiger in OpenAIREM.D. Jackson;
+5 AuthorsM.D. Jackson
M.D. Jackson in OpenAIRED. Petrovskyy;C. Jacquemyn;
C. Jacquemyn
C. Jacquemyn in OpenAIRES. Geiger;
S. Geiger
S. Geiger in OpenAIREM.D. Jackson;
M.D. Jackson
M.D. Jackson in OpenAIREG.J. Hampson;
J.D. Machado Silva;G.J. Hampson
G.J. Hampson in OpenAIRES. Judice;
S. Judice
S. Judice in OpenAIREF. Rahman;
M. Costa Sousa;F. Rahman
F. Rahman in OpenAIREhandle: 10044/1/102908
Sketch-based interface and modelling is an approach to reservoir modelling that allows rapid and intuitive creation of 3D reservoir models to test and evaluate geological concepts and hypotheses and thus explore the impact of geological uncertainty on reservoir behaviour. A key advantage of such modelling is the quick creation and quantitative evaluation of reservoir model prototypes. Flow diagnostics capture key aspects of reservoir flow behaviour under simplified physical conditions that enable the rapid solution of the governing equations, and are essential for such quantitative evaluation. In this paper, we demonstrate a novel and highly efficient implementation of a flow diagnostics framework, illustrated with applications to geological storage of CO2. Our implementation permits ‘on-the-fly’ estimation of the key reservoir properties that control CO2 migration and storage during the active injection period when viscous forces dominate. The results substantially improve the efficiency of traditional reservoir modelling and simulation workflows by highlighting key reservoir uncertainties that need to be evaluated in subsequent full-physics reservoir simulations that account for the complex interplay of viscous, gravity, and capillary forces. The methods are implemented in the open-source Rapid Reservoir Modelling software, which includes a simple to use graphical user interface with no steep learning curve. We present proof-of-concept studies of the new flow diagnostics implementation to investigate the CO2 storage potential of sketched 3D models of shallow marine sandstone tongues and deep water slope channels.
Imperial College Lon... arrow_drop_down Imperial College London: SpiralArticle . 2023License: CC BYFull-Text: http://hdl.handle.net/10044/1/102908Data sources: Bielefeld Academic Search Engine (BASE)International Journal of Greenhouse Gas ControlArticle . 2023 . Peer-reviewedLicense: CC BYData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.ijggc.2023.103855&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu3 citations 3 popularity Average influence Average impulse Average Powered by BIP!
more_vert Imperial College Lon... arrow_drop_down Imperial College London: SpiralArticle . 2023License: CC BYFull-Text: http://hdl.handle.net/10044/1/102908Data sources: Bielefeld Academic Search Engine (BASE)International Journal of Greenhouse Gas ControlArticle . 2023 . Peer-reviewedLicense: CC BYData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.ijggc.2023.103855&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Other literature type , Journal 2019 Germany, United KingdomPublisher:Copernicus GmbH Authors:Matthew Gidden;
Matthew Gidden
Matthew Gidden in OpenAIREMalte Meinshausen;
Malte Meinshausen;Malte Meinshausen
Malte Meinshausen in OpenAIREKeywan Riahi;
+9 AuthorsKeywan Riahi
Keywan Riahi in OpenAIREMatthew Gidden;
Matthew Gidden
Matthew Gidden in OpenAIREMalte Meinshausen;
Malte Meinshausen;Malte Meinshausen
Malte Meinshausen in OpenAIREKeywan Riahi;
Keywan Riahi; Daniel Huppmann; Leon Clarke;Keywan Riahi
Keywan Riahi in OpenAIREJoeri Rogelj;
Joeri Rogelj; Joeri Rogelj;Joeri Rogelj
Joeri Rogelj in OpenAIREZebedee Nicholls;
Zebedee Nicholls
Zebedee Nicholls in OpenAIREVolker Krey;
Volker Krey;Volker Krey
Volker Krey in OpenAIREpmid: 31534246
handle: 10044/1/73971
<p>To understand how global warming can be kept well-below 2&#176;C and even 1.5&#176;C, climate policy uses scenarios that describe how society could transform in order to reduce its greenhouse gas emissions. Such scenario are typically created with integrated assessment models that include a representation of the economy, and the energy, land-use, and industrial system. However, current climate change scenarios have a key weakness in that they typically focus on reaching specific climate goals in 2100 only. <br><br>This choice results in risky pathways that delay action and seemingly inevitably rely on large quantities of carbon-dioxide removal after mid-century. Here we propose a framework that more closely reflects the intentions of the UN Paris Agreement. It focusses on reaching a peak in global warming with either stabilisation or reversal thereafter. This approach provides a critical extension of the widely used Shared Socioecononomic Pathways (SSP) framework and reveals a more diverse picture: an inevitable transition period of aggressive near-term climate action to reach carbon neutrality can be followed by a variety of long-term states. It allows policymakers to explicitly consider near-term climate strategies in the context of intergenerational equity and long-term sustainability.</p>
add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.5194/egusphere-egu2020-10262&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess RoutesGreen bronze 347 citations 347 popularity Top 0.1% influence Top 1% impulse Top 0.1% Powered by BIP!
visibility 108visibility views 108 download downloads 133 Powered bymore_vert add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.5194/egusphere-egu2020-10262&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article 2022 FrancePublisher:SAGE Publications Authors:Julien Guiraud;
Giovanni Addolorato; Mariangela Antonelli; Henri-Jean Aubin; +29 AuthorsJulien Guiraud
Julien Guiraud in OpenAIREJulien Guiraud;
Giovanni Addolorato; Mariangela Antonelli; Henri-Jean Aubin; Andrea de Bejczy; Amine Benyamina; Roberto Cacciaglia;Julien Guiraud
Julien Guiraud in OpenAIREFabio Caputo;
Maurice Dematteis;Fabio Caputo
Fabio Caputo in OpenAIREAnna Ferrulli;
Anna E Goudriaan; Antoni Gual; Otto-Michael Lesch; Icro Maremmani;Anna Ferrulli
Anna Ferrulli in OpenAIREAntonio Mirijello;
David J Nutt; François Paille;Antonio Mirijello
Antonio Mirijello in OpenAIREPascal Perney;
Roch Poulnais; Quentin Raffaillac; Jürgen Rehm;Pascal Perney
Pascal Perney in OpenAIREBenjamin Rolland;
Claudia Rotondo; Bruno Scherrer; Nicolas Simon; Katrin Skala; Bo Söderpalm; Lorenzo Somaini; Wolfgang H Sommer; Rainer Spanagel; Gabriele A Vassallo; Henriette Walter; Wim van den Brink;Benjamin Rolland
Benjamin Rolland in OpenAIREBackground: Sodium oxybate (SMO) has been shown to be effective in the maintenance of abstinence (MoA) in alcohol-dependent patients in a series of small randomized controlled trials (RCTs). These results needed to be confirmed by a large trial investigating the treatment effect and its sustainability after medication discontinuation. Aims: To confirm the SMO effect on (sustained) MoA in detoxified alcohol-dependent patients. Methods: Large double-blind, randomized, placebo-controlled trial in detoxified adult alcohol-dependent outpatients (80% men) from 11 sites in four European countries. Patients were randomized to 6 months SMO (3.3–3.9 g/day) or placebo followed by a 6-month medication-free period. Primary outcome was the cumulative abstinence duration (CAD) during the 6-month treatment period defined as the number of days with no alcohol use. Secondary outcomes included CAD during the 12-month study period. Results: Of the 314 alcohol-dependent patients randomized, 154 received SMO and 160 received placebo. Based on the pre-specified fixed-effect two-way analysis of variance including the treatment-by-site interaction, SMO showed efficacy in CAD during the 6-month treatment period: mean difference +43.1 days, 95% confidence interval (17.6–68.5; p = 0.001). Since significant heterogeneity of effect across sites and unequal sample sizes among sites ( n = 3–66) were identified, a site-level random meta-analysis was performed with results supporting the pre-specified analysis: mean difference +32.4 days, p = 0.014. The SMO effect was sustained during the medication-free follow-up period. SMO was well-tolerated. Conclusions: Results of this large RCT in alcohol-dependent patients demonstrated a significant and clinically relevant sustained effect of SMO on CAD. Trial registration: ClinicalTrials.gov Identifier: NCT04648423
Université Grenoble ... arrow_drop_down Université Grenoble Alpes: HALArticle . 2022Full-Text: https://inserm.hal.science/inserm-04057658Data sources: Bielefeld Academic Search Engine (BASE)Université de Versailles Saint-Quentin-en-Yvelines: HAL-UVSQArticle . 2022Full-Text: https://inserm.hal.science/inserm-04057658Data sources: Bielefeld Academic Search Engine (BASE)Université Jean Monnet – Saint-Etienne: HALArticle . 2022Full-Text: https://inserm.hal.science/inserm-04057658Data sources: Bielefeld Academic Search Engine (BASE)add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
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more_vert Université Grenoble ... arrow_drop_down Université Grenoble Alpes: HALArticle . 2022Full-Text: https://inserm.hal.science/inserm-04057658Data sources: Bielefeld Academic Search Engine (BASE)Université de Versailles Saint-Quentin-en-Yvelines: HAL-UVSQArticle . 2022Full-Text: https://inserm.hal.science/inserm-04057658Data sources: Bielefeld Academic Search Engine (BASE)Université Jean Monnet – Saint-Etienne: HALArticle . 2022Full-Text: https://inserm.hal.science/inserm-04057658Data sources: Bielefeld Academic Search Engine (BASE)add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article 2022Publisher:Elsevier BV Applied Thermal Engi... arrow_drop_down Applied Thermal EngineeringArticle . 2022 . Peer-reviewedLicense: Elsevier TDMData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.eu5 citations 5 popularity Average influence Average impulse Top 10% Powered by BIP!
more_vert Applied Thermal Engi... arrow_drop_down Applied Thermal EngineeringArticle . 2022 . Peer-reviewedLicense: Elsevier TDMData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article 2023 United KingdomPublisher:Elsevier BV Publicly fundedSchwidtal, JM; Piccini, P; Troncia, M; Chitchyan, R;Montakhabi, M;
Francis, C; Gorbatcheva, A; Capper, T; Mustafa, MA; Andoni, M; Robu, V; Bahloul, M; Scott, IJ; Mbavarira, T; España, JM; Kiesling, L;Montakhabi, M
Montakhabi, M in OpenAIREhandle: 10044/1/105817
Imperial College Lon... arrow_drop_down Imperial College London: SpiralArticle . 2023License: CC BYFull-Text: http://hdl.handle.net/10044/1/105817Data sources: Bielefeld Academic Search Engine (BASE)Renewable and Sustainable Energy ReviewsArticle . 2023 . Peer-reviewedLicense: CC BYData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.euAccess RoutesGreen hybrid 0 citations 0 popularity Average influence Average impulse Average Powered by BIP!
visibility 2visibility views 2 download downloads 4 Powered bymore_vert Imperial College Lon... arrow_drop_down Imperial College London: SpiralArticle . 2023License: CC BYFull-Text: http://hdl.handle.net/10044/1/105817Data sources: Bielefeld Academic Search Engine (BASE)Renewable and Sustainable Energy ReviewsArticle . 2023 . Peer-reviewedLicense: CC BYData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
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