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description Publicationkeyboard_double_arrow_right Article , Journal 2014Publisher:Elsevier BV Povilaitis, M.; Kljenak, I.; Sathiah, P.; Bentaib, A.; Bleyer, A.; Meynet, N.; Chaumeix, N.; Schramm, B.; Höhne, M.; Kostka, P.; Movahed, M.; Worapittayaporn, S.; Brähler, T.; Seok-Kang, H.;Abstract In case of a core melt-down accident in a light water nuclear reactor, hydrogen is produced during reactor core degradation and released into the reactor building. This subsequently creates a combustion hazard. A local ignition of the combustible mixture may generate standing flames or initially slow propagating flames. Depending on geometry, mixture composition and turbulence level, the flame can accelerate or be quenched after a certain distance. The loads generated by the combustion process (increase of the containment atmosphere pressure and temperature) may threaten the integrity of the containment building and of internal walls and equipment. Turbulent deflagration flames may generate high pressure pulses, temperature peaks, shock waves and large pressure gradients which could severely damage specific containment components, internal walls and/or safety equipment. The evaluation of such loads requires validated codes which can be used with a high level of confidence. Currently, turbulence and steam effect on flame acceleration, flame deceleration and flame quenching mechanisms are not well reproduced by combustion models usually implemented in safety tools and further model enhancement and validation are still needed. For this purpose, two hydrogen deflagration benchmark exercises have been organised in the framework of the SARNET network. The first benchmark was focused on turbulence effect on flame propagation. For this purpose, three tests performed in the ENACCEF facility were considered. They concern vertical flame propagation in an initially homogenous mixture with 13 vol.% hydrogen content and different geometrical configurations. Three blockage ratios of 0, 0.33 and 0.6 were considered to generate different levels of turbulence. The second benchmark objective was the investigation of the diluting effect on flame propagation. Thus, three tests performed in the ENACCEF facility using the same blockage ratio of 0.63 and three different initial gas compositions (with 10, 20 and 30 vol.% diluents) have been considered. Since ENACCEF runs at ambient temperature, a surrogate to steam was used consisting of a mixture of 0.6He + 0.4CO 2 on molar basis. This paper aims to present the benchmarks conclusions regarding the ability of LP and CFD combustion models to predict the effect of turbulence and diluent on flame propagation.
add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.anucene.2014.07.012&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu24 citations 24 popularity Top 10% influence Top 10% impulse Top 10% Powered by BIP!
more_vert add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.anucene.2014.07.012&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Preprint 2022Embargo end date: 01 Jan 2020 United KingdomPublisher:Elsevier BV Funded by:EC | ReUseHeatEC| ReUseHeatAuthors: Volodina, Victoria; Wheatcroft, Edward; Wynn, Henry;District heating is a network of pipes through which heat is delivered from a centralised source. It is expected to play an important role in the decarbonisation of the energy sector in the coming years. In district heating, heat is traditionally generated through fossil fuels, often with combined heat and power (CHP) units. However, increasingly, waste heat is being used as a low carbon alternative, either directly or, for low temperature sources, via a heat pump. The design of district heating often has competing objectives: the need for inexpensive energy and meeting low carbon targets. In addition, the planning of district heating schemes is subject to multiple sources of uncertainty such as variability in heat demand and energy prices. This paper proposes a decision support tool to analyse and compare system designs for district heating under uncertainty using stochastic ordering (dominance). Contrary to traditional uncertainty metrics that provide statistical summaries and impose total ordering, stochastic ordering is a partial ordering and operates with full probability distributions. In our analysis, we apply the orderings in the mean and dispersion to the waste heat recovery problem in Brunswick, Germany.
Sustainable Energy G... arrow_drop_down Sustainable Energy Grids and NetworksArticle . 2022 . Peer-reviewedLicense: CC BYData sources: Crossrefhttps://dx.doi.org/10.48550/ar...Article . 2020License: arXiv Non-Exclusive DistributionData sources: DataciteSustainable Energy Grids and NetworksArticle . 2022 . Peer-reviewedData sources: European Union Open Data Portaladd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.segan.2022.100634&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess RoutesGreen hybrid 4 citations 4 popularity Top 10% influence Average impulse Average Powered by BIP!
more_vert Sustainable Energy G... arrow_drop_down Sustainable Energy Grids and NetworksArticle . 2022 . Peer-reviewedLicense: CC BYData sources: Crossrefhttps://dx.doi.org/10.48550/ar...Article . 2020License: arXiv Non-Exclusive DistributionData sources: DataciteSustainable Energy Grids and NetworksArticle . 2022 . Peer-reviewedData sources: European Union Open Data Portaladd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.segan.2022.100634&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Journal , Other literature type 2017Publisher:MDPI AG Dawit Guta; Jose Jara; Narayan Adhikari; Qiu Chen; Varun Gaur; Alisher Mirzabaev;Access to reliable and affordable energy is vital for sustainable development. In the off-grid areas of developing countries, decentralized energy solutions have received increasing attention due to their contributions to reducing poverty. However, most of the rural population in many developing countries still has little or no access to modern energy technologies. This paper assesses the factors that determine the successes and failures of decentralized energy solutions based on local harmonized case studies from heterogeneous contexts from Asia, sub-Saharan Africa, and South America. The case studies were analyzed through the coupled lenses of energy transition and the Water–Energy–Food Security (WEF) Nexus. The findings indicate that access to modern decentralized energy solutions has not resulted in complete energy transitions due to various tradeoffs with the other domains of the WEF Nexus. On the other hand, the case studies point at the potential for improvements in food security, incomes, health, the empowerment of women, and resource conservation when synergies between decentralized energy solutions and other components of the WEF Nexus are present.
Resources arrow_drop_down ResourcesOther literature type . 2017License: CC BYFull-Text: http://www.mdpi.com/2079-9276/6/3/24/pdfData sources: Multidisciplinary Digital Publishing Instituteadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.3390/resources6030024&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess Routesgold 35 citations 35 popularity Top 10% influence Top 10% impulse Top 10% Powered by BIP!
more_vert Resources arrow_drop_down ResourcesOther literature type . 2017License: CC BYFull-Text: http://www.mdpi.com/2079-9276/6/3/24/pdfData sources: Multidisciplinary Digital Publishing Instituteadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.3390/resources6030024&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Other literature type 2023Publisher:MDPI AG Publicly fundedFunded by:EC | SCOREEC| SCOREAuthors: Tasneem Ahmed; Leo Creedon; Salem Gharbia;Unequivocal change in the climate system has put coastal regions around the world at increasing risk from climate-related hazards. Monitoring the coast is often difficult and expensive, resulting in sparse monitoring equipment lacking in sufficient temporal and spatial coverage. Thus, low-cost methods to monitor the coast at finer temporal and spatial resolution are imperative for climate resilience along the world’s coasts. Exploiting such low-cost methods for the development of early warning support could be invaluable to coastal settlements. This paper aims to provide the most up-to-date low-cost techniques developed and used in the last decade for monitoring coastal hazards and their forcing agents via systematic review of the peer-reviewed literature in three scientific databases: Scopus, Web of Science and ScienceDirect. A total of 60 papers retrieved from these databases through the preferred reporting items for systematic reviews and meta-analyses (PRISMA) protocol were analysed in detail to yield different categories of low-cost sensors. These sensors span the entire domain for monitoring coastal hazards, as they focus on monitoring coastal zone characteristics (e.g., topography), forcing agents (e.g., water levels), and the hazards themselves (e.g., coastal flooding). It was found from the meta-analysis of the retrieved papers that terrestrial photogrammetry, followed by aerial photogrammetry, was the most widely used technique for monitoring different coastal hazards, mainly coastal erosion and shoreline change. Different monitoring techniques are available to monitor the same hazard/forcing agent, for instance, unmanned aerial vehicles (UAVs), time-lapse cameras, and wireless sensor networks (WSNs) for monitoring coastal morphological changes such as beach erosion, creating opportunities to not only select but also combine different techniques to meet specific monitoring objectives. The sensors considered in this paper are useful for monitoring the most pressing challenges in coastal zones due to the changing climate. Such a review could be extended to encompass more sensors and variables in the future due to the systematic approach of this review. This study is the first to systematically review a wide range of low-cost sensors available for the monitoring of coastal zones in the context of changing climate and is expected to benefit coastal researchers and managers to choose suitable low-cost sensors to meet their desired objectives for the regular monitoring of the coast to increase climate resilience.
Sensors arrow_drop_down SensorsArticleLicense: CC BYFull-Text: https://www.mdpi.com/1424-8220/23/3/1717/pdfData sources: Sygmaadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.3390/s23031717&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess RoutesGreen gold 7 citations 7 popularity Top 10% influence Average impulse Top 10% Powered by BIP!
visibility 5visibility views 5 download downloads 8 Powered bymore_vert Sensors arrow_drop_down SensorsArticleLicense: CC BYFull-Text: https://www.mdpi.com/1424-8220/23/3/1717/pdfData sources: Sygmaadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.3390/s23031717&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Project deliverable , Other literature type 2023Publisher:Zenodo Funded by:EC | ePANACEAEC| ePANACEAAuthors: Andreas Androutsopoulos; Maria Bololia; Elpida Polychroni;The EU has set clear targets regarding energy conservation of buildings and heavily supports activities towards achieving these targets on a European scale. The Green Deal, renovation wave, Energy Performance of Buildings Directive (EPBD) and Energy Efficiency Directive (EED) are some examples of EU's actions. For more than a decade, Energy Performance Certificates provide detailed data about the current energy needs of a building/building unit as well as information about the building construction and systems. A Building Renovation Passport (BRP) has, on a European level lately, been conceived as a tool that can stimulate cost-effective renovation in the form of a long-term basis, step-by-step deep renovation roadmap following defined quality criteria, and outline energy renovation measures that will improve the energy performance of the building. A Digital Building Logbook (DBL) is another tool that can serve as an archive where all building information can be stored and continuously updated. In this way, a full record of the building history will be electronically available with data regarding construction plans and permits, maintenance and system replacement activities, energy and heat consumption and production, etc. Building Renovation Passports and the Digital Building Logbook are tools that can help in achieving energy efficiency in existing buildings and contribute to reaching the EU renovation wave goals. The objective of this report is to investigate how the current EPC schemes best make the link towards the BRP and the DBL to further incentivise and stimulate cost-effective deep energy renovations of buildings across Europe. Three surveys were carried out to collect relevant information about the current status of the EPC data records and to identify stakeholders' potential needs, perceptions, thoughts and expectations, regarding a future connection between the EPC and the BRP or DBL. These surveys were prepared in two forms: using an excel file format circulated via email, and through an online questionnaire. Their completion was carried out by 16 countries. Regarding the EPCs, the state or regional energy agencies are the owner of the EPC data records and make full use of them. Their current main usage is for statistical reasons in the majority of the countries and their access is publicly available in half of the responding countries. Many common data is stored in the EPC database which can be linked with other tools (half of the EPC databases are already linked with another source). Regarding the BRP, a review of existing European schemes showed that successful BRPs have combined the renovation advice with financial support, legal requirements and/or communication campaigns. An important factor of the BRP is that it should be issued by a qualified expert and should provide customised measures for the specific building together with the investment costs per renovation measure(s). The DBL analysis showed that it should provide access to building information and contribute to better decision-making for future interventions as well as operation, use and maintenance records. The building owner/user is proposed to have full access to the logbook and provide/input about energy bills and building plans/construction materials info. An important aspect is that every time the building undergoes intervention works, the DBL should be updated accordingly. The most important barrier is the lack of motivation to update the DBL contents followed by the absence of synergies and consistency with other tools. Another interesting finding is that both BRP and DBL should be fed automatically by EPC data without any user interference. There is a clear possible interconnection between EPC data and BRP and DBL future contents. In addition, BRP can be an instrument to increase the renovation rates and DBLs are necessary for the management of buildings' information. The linkage of EPC data and BRP and DBL can be strengthened by introducing BRP and DBL as voluntary schemes under national incentives and should be fully implemented once they have demonstrated acceptance by the stakeholders.
add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.5281/zenodo.10265586&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess RoutesGreen 0 citations 0 popularity Average influence Average impulse Average Powered by BIP!
more_vert add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.5281/zenodo.10265586&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article 2022Publisher:Copernicus GmbH Funded by:EC | zEPHYREC| zEPHYRAuthors: Kartik Venkatraman; Trond-Ola Hågbo; Sophia Buckingham; Knut Erik Teigen Giljarhus;doi: 10.5194/wes-2021-142
Abstract. The assessment of wind conditions in complex terrain requires the use of Computational Fluid Dynamics (CFD) simulations incorporating an accurate parameterization of forest canopy effects and variable thermal stability effects. This study aims to investigate how incorporating the presence of trees can improve flow predictions. A three-dimensional steady Reynolds-averaged Navier-Stokes (RANS) equations model is set up using OpenFOAM to simulate the flow over a complex terrain site comprising two parallel ridges located near Perdigão, Portugal. A 7.5 km × 7.5 km terrain of the Perdigao site is constructed from elevation data centered around a 100 m met-mast located on the northeast ridge. A 30-min averaged stationary period corresponding to near-neutral conditions on a single met-mast tower is simulated. The impact of incorporating different source terms is studied such as forest canopy, Coriolis forces as well as also buoyancy forces. The prediction capability of the models is analyzed for different groups of towers on the South-West ridge, inside the valley, and on the North-East ridge based on the flow topology. The inclusion of a canopy model is shown to improve predictions close to the ground for most of the towers, while reducing prediction accuracy on top of the ridges, illustrating the need to represent terrain heterogeneity.
https://doi.org/10.5... arrow_drop_down https://doi.org/10.5194/wes-20...Article . 2022 . Peer-reviewedLicense: CC BYData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.5194/wes-2021-142&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess Routeshybrid 0 citations 0 popularity Average influence Average impulse Average Powered by BIP!
more_vert https://doi.org/10.5... arrow_drop_down https://doi.org/10.5194/wes-20...Article . 2022 . Peer-reviewedLicense: CC BYData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.5194/wes-2021-142&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Journal 2017 United KingdomPublisher:Elsevier BV Funded by:UKRI | Cretaceous-Paleocene-Eoce..., EC | TGRES, UKRI | The Descent into the Iceh... +2 projectsUKRI| Cretaceous-Paleocene-Eocene: Exploring Climate and Climate Sensitivity ,EC| TGRES ,UKRI| The Descent into the Icehouse ,UKRI| Terrestrial methane cycling during Paleogene greenhouse climates ,UKRI| Cretaceous-Paleocene-Eocene: Exploring Climate and Climate SensitivityInglis, Gordon N.; Collinson, Margaret E.; Riegel, Walter; Wilde, Volker; Farnsworth, Alexander; Lunt, Daniel J.; Valdes, Paul; Robson, Brittany E.; Scott, Andrew C.; Lenz, Olaf K.; Naafs, B. David A.; Pancost, Richard D.;Abstract Branched glycerol dialkyl glycerol tetraethers (brGDGTs) are increasingly used to reconstruct mean annual air temperature (MAAT) during the early Paleogene. However, the application of this proxy in coal deposits is limited and brGDGTs have only been detected in immature coals (i.e. lignites). Using samples recovered from Schoningen, Germany (∼48°N palaeolatitude), we provide the first detailed study into the occurrence and distribution of brGDGTs through a sequence of early Eocene lignites and associated interbeds. BrGDGTs are abundant and present in every sample. In comparison to modern studies, changes in vegetation type do not appear to significantly impact brGDGT distributions; however, there are subtle differences between lignites – representing peat-forming environments – and siliciclastic nearshore marine interbed depositional environments. Using the most recent brGDGT temperature calibration (MATmr) developed for soils, we generate the first continental temperature record from central-western continental Europe through the early Eocene. Lignite-derived MAAT estimates range from 23 to 26 °C while those derived from the nearshore marine interbeds exceed 20 °C. These estimates are consistent with other mid-latitude environments and model simulations, indicating enhanced mid-latitude, early Eocene warmth. In the basal part of the section studied, warming is recorded in both the lignites (∼2 °C) and nearshore marine interbeds (∼2–3 °C). This culminates in a long-term temperature maximum, likely including the Early Eocene Climatic Optimum (EECO). Although this long-term warming trend is relatively well established in the marine realm, it has rarely been shown in terrestrial settings. Using a suite of model simulations we show that the magnitude of warming at Schoningen is broadly consistent with a doubling of CO2, in agreement with late Paleocene and early Eocene pCO2 estimates.
e-Prints Soton arrow_drop_down e-Prints SotonArticle . 2017License: CC BY NC NDData sources: Bielefeld Academic Search Engine (BASE)Earth and Planetary Science LettersArticle . 2017 . Peer-reviewedLicense: CC BY NC NDData sources: CrossrefEarth and Planetary Science LettersArticle . 2017License: CC BY NC NDData sources: BASE (Open Access Aggregator)Fachrepositorium LebenswissenschaftenArticle . 2016License: CC BY NC NDData sources: Fachrepositorium LebenswissenschaftenUniversity of Bristol: Bristol ResearchArticle . 2017Data sources: Bielefeld Academic Search Engine (BASE)http://dx.doi.org/10.1016/j.ep...Article . Peer-reviewedData sources: European Union Open Data Portaladd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.epsl.2016.12.009&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess RoutesGreen hybrid 48 citations 48 popularity Top 10% influence Top 10% impulse Top 1% Powered by BIP!
more_vert e-Prints Soton arrow_drop_down e-Prints SotonArticle . 2017License: CC BY NC NDData sources: Bielefeld Academic Search Engine (BASE)Earth and Planetary Science LettersArticle . 2017 . Peer-reviewedLicense: CC BY NC NDData sources: CrossrefEarth and Planetary Science LettersArticle . 2017License: CC BY NC NDData sources: BASE (Open Access Aggregator)Fachrepositorium LebenswissenschaftenArticle . 2016License: CC BY NC NDData sources: Fachrepositorium LebenswissenschaftenUniversity of Bristol: Bristol ResearchArticle . 2017Data sources: Bielefeld Academic Search Engine (BASE)http://dx.doi.org/10.1016/j.ep...Article . Peer-reviewedData sources: European Union Open Data Portaladd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.epsl.2016.12.009&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Journal , Other literature type 2020Publisher:MDPI AG Funded by:EC | FAirWAYEC| FAirWAYAuthors: Klages, Susanne; Heidecke, Claudia; Osterburg, Bernhard;doi: 10.3390/w12061519
The hot summer of 2018 posed many challenges with regard to water shortages and yield losses, especially for agricultural production. These agricultural impacts might further pose consequent threats for the environment. In this paper, we deduce the impact of droughts on agricultural land management and on water quality owing to nitrate pollution. Using national statistics, we calculate a Germany-wide soil surface nitrogen budget for 2018 and deduce the additional N surplus owing to the dry weather conditions. Using a model farm approach, we compare fertilization practices and legal restrictions for arable and pig breeding farms. The results show that, nationwide, at least 464 kt of nitrogen were not transferred to plant biomass in 2018, which equals an additional average nitrogen surplus of 30 kg/ha. The surplus would even have amounted to 43 kg/ha, if farmers had continued their fertilization practice from preceding years, but German farmers applied 161 kt less nitrogen in 2018 than in the year before, presumably as a result of the new implications of the Nitrates Directive, and, especially on grassland, owing to the drought. As nitrogen surplus is regarded as an “agri-drinking water indicator” (ADWI), an increase of the surplus entails water pollution with nitrates. The examples of the model farms show that fertilization regimes with high shares of organic fertilizers produce higher nitrogen surpluses. Owing to the elevated concentrations on residual nitrogen in soils, the fertilization needs of crops in spring 2019 were less pronounced than in preceding years. Thus, the quantity of the continuously produced manure in livestock farms puts additional pressure on existing storage capacities. This may particularly be the case in the hot-spot regions of animal breeding in the north-west of Germany, where manure production, biogas plants, and manure imports are accumulating. The paper concludes that water shortages under climate change not only impact agricultural production and yields, but also place further challenges and threats to nutrient management and the environment. The paper discusses preventive and emergency management options for agriculture to support farmers in extremely dry and hot conditions.
Water arrow_drop_down WaterOther literature type . 2020License: CC BYFull-Text: http://www.mdpi.com/2073-4441/12/6/1519/pdfData sources: Multidisciplinary Digital Publishing InstituteWaterArticleLicense: CC BYFull-Text: https://www.mdpi.com/2073-4441/12/6/1519/pdfData sources: Sygmaadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.3390/w12061519&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess Routesgold 24 citations 24 popularity Top 10% influence Top 10% impulse Top 10% Powered by BIP!
more_vert Water arrow_drop_down WaterOther literature type . 2020License: CC BYFull-Text: http://www.mdpi.com/2073-4441/12/6/1519/pdfData sources: Multidisciplinary Digital Publishing InstituteWaterArticleLicense: CC BYFull-Text: https://www.mdpi.com/2073-4441/12/6/1519/pdfData sources: Sygmaadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.3390/w12061519&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Other literature type , Journal 2013Embargo end date: 01 Jan 2013 SwitzerlandPublisher:Copernicus GmbH Authors: Jannis Epting; Falk Händel; Falk Händel; Peter Huggenberger;Abstract. This study presents the development of tools for the sustainable thermal management of a shallow unconsolidated urban groundwater body in the city of Basel (Switzerland). The concept of the investigations is based on (1) a characterization of the present thermal state of the urban groundwater body, and (2) the evaluation of potential mitigation measures for the future thermal management of specific regions within the groundwater body. The investigations focus on thermal processes down-gradient of thermal groundwater use, effects of heated buildings in the subsurface as well as the thermal influence of river–groundwater interaction. Investigation methods include (1) short- and long-term data analysis, (2) high-resolution multilevel groundwater temperature monitoring, as well as (3) 3-D numerical groundwater flow and heat transport modeling and scenario development. The combination of these methods allows for the quantifying of the thermal influences on the investigated urban groundwater body, including the influences of thermal groundwater use and heated subsurface constructions. Subsequently, first implications for management strategies are discussed, including minimizing further groundwater temperature increase, targeting "potential natural" groundwater temperatures for specific aquifer regions and exploiting the thermal potential.
University of Basel:... arrow_drop_down University of Basel: edocArticle . 2013License: CC BYData sources: Bielefeld Academic Search Engine (BASE)Hydrology and Earth System Sciences (HESS)Article . 2013 . Peer-reviewedLicense: CC BYData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.5194/hess-17-1851-2013&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess RoutesGreen gold 88 citations 88 popularity Top 10% influence Top 10% impulse Top 10% Powered by BIP!
more_vert University of Basel:... arrow_drop_down University of Basel: edocArticle . 2013License: CC BYData sources: Bielefeld Academic Search Engine (BASE)Hydrology and Earth System Sciences (HESS)Article . 2013 . Peer-reviewedLicense: CC BYData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.5194/hess-17-1851-2013&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Other literature type 2023 SpainPublisher:Ovid Technologies (Wolters Kluwer Health) Funded by:EC | NextGen IO, NIH | Liver-enriched Transcript...EC| NextGen IO ,NIH| Liver-enriched Transcription Factors as Prognostic Markers and Therapeutic Targets in Alcoholic HepatitisAuthors: Goikoetxea-Usandizaga, Naroa; Bravo, Miren; Egia-Mendikute, Leire; Abecia, Leticia; +38 AuthorsGoikoetxea-Usandizaga, Naroa; Bravo, Miren; Egia-Mendikute, Leire; Abecia, Leticia; Serrano-Maciá, Marina; Urdinguio, Rocío G.; Clos-García, Marc; Rodríguez-Agudo, Rubén; Araujo-Legido, Raquel; López-Bermudo, Lucía; Delgado, Teresa C.; Lachiondo-Ortega, Sofía; González-Recio, Irene; Gil-Pitarch, Clàudia; Peña-Cearra, Ainize; Simón, Jorge; Benedé-Ubieto, Raquel; Ariño, Silvia; Herranz, Jose M.; Azkargorta, Mikel; Salazar-Bermeo, Julio; Martí, Nuria; Varela-Rey, Marta; Falcón-Pérez, Juan M.; Lorenzo, Óscar; Nogueiras, Rubén; Elortza, Félix; Nevzorova, Yulia; Cubero, Francisco J.; Saura, Domingo; Martínez-Cruz, Luis Alfonso; Sabio, Guadalupe; Palazón, Asís; Palazón, Asís; Sancho-Bru, Pau; Elguezabal, Natalia; Fraga, Mario F.; Ávila, Matías A.; Bataller, Ramón; Marín, José J. G.; Martín, Franz; Martínez-Chantar, María Luz;Background and Aims: Alcohol-associated liver disease (ALD) accounts for 70% of liver-related deaths in Europe, with no effective approved therapies. Although mitochondrial dysfunction is one of the earliest manifestations of alcohol-induced injury, restoring mitochondrial activity remains a problematic strategy due to oxidative stress. Here, we identify methylation-controlled J protein (MCJ) as a mediator for ALD progression and hypothesize that targeting MCJ may help in recovering mitochondrial fitness without collateral oxidative damage. Approach and Results: C57BL/6 mice [wild-type (Wt)] Mcj knockout and Mcj liver-specific silencing (MCJ-LSS) underwent the NIAAA dietary protocol (Lieber-DeCarli diet containing 5% (vol/vol) ethanol for 10 days, plus a single binge ethanol feeding at day 11). To evaluate the impact of a restored mitochondrial activity in ALD, the liver, gut, and pancreas were characterized, focusing on lipid metabolism, glucose homeostasis, intestinal permeability, and microbiota composition. MCJ, a protein acting as an endogenous negative regulator of mitochondrial respiration, is downregulated in the early stages of ALD and increases with the severity of the disease. Whole-body deficiency of MCJ is detrimental during ALD because it exacerbates the systemic effects of alcohol abuse through altered intestinal permeability, increased endotoxemia, and dysregulation of pancreatic function, which overall worsens liver injury. On the other hand, liver-specific Mcj silencing prevents main ALD hallmarks, that is, mitochondrial dysfunction, steatosis, inflammation, and oxidative stress, as it restores the NAD+/NADH ratio and SIRT1 function, hence preventing de novo lipogenesis and improving lipid oxidation. Conclusions: Improving mitochondrial respiration by liver-specific Mcj silencing might become a novel therapeutic approach for treating ALD.
Hepatology arrow_drop_down HepatologyArticleLicense: http://creativecommons.org/licenses/by-nc-nd/4.0/ http://creativecommons.org/licenses/by-nc-nd/4.0/Data sources: SygmaHepatologyArticle . 2023 . Peer-reviewedLicense: http://creativecommons.org/licenses/by-nc-nd/4.0/ http://creativecommons.org/licenses/by-nc-nd/4.0/Data sources: CrossrefRecolector de Ciencia Abierta, RECOLECTAArticle . 2023Data sources: Recolector de Ciencia Abierta, RECOLECTARecolector de Ciencia Abierta, RECOLECTAArticle . 2023License: CC BY NC NDData sources: Recolector de Ciencia Abierta, RECOLECTAadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1097/hep.0000000000000303&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess RoutesGreen hybrid 12 citations 12 popularity Top 10% influence Average impulse Top 10% Powered by BIP!
visibility 49visibility views 49 download downloads 118 Powered bymore_vert Hepatology arrow_drop_down HepatologyArticleLicense: http://creativecommons.org/licenses/by-nc-nd/4.0/ http://creativecommons.org/licenses/by-nc-nd/4.0/Data sources: SygmaHepatologyArticle . 2023 . Peer-reviewedLicense: http://creativecommons.org/licenses/by-nc-nd/4.0/ http://creativecommons.org/licenses/by-nc-nd/4.0/Data sources: CrossrefRecolector de Ciencia Abierta, RECOLECTAArticle . 2023Data sources: Recolector de Ciencia Abierta, RECOLECTARecolector de Ciencia Abierta, RECOLECTAArticle . 2023License: CC BY NC NDData sources: Recolector de Ciencia Abierta, RECOLECTAadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
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description Publicationkeyboard_double_arrow_right Article , Journal 2014Publisher:Elsevier BV Povilaitis, M.; Kljenak, I.; Sathiah, P.; Bentaib, A.; Bleyer, A.; Meynet, N.; Chaumeix, N.; Schramm, B.; Höhne, M.; Kostka, P.; Movahed, M.; Worapittayaporn, S.; Brähler, T.; Seok-Kang, H.;Abstract In case of a core melt-down accident in a light water nuclear reactor, hydrogen is produced during reactor core degradation and released into the reactor building. This subsequently creates a combustion hazard. A local ignition of the combustible mixture may generate standing flames or initially slow propagating flames. Depending on geometry, mixture composition and turbulence level, the flame can accelerate or be quenched after a certain distance. The loads generated by the combustion process (increase of the containment atmosphere pressure and temperature) may threaten the integrity of the containment building and of internal walls and equipment. Turbulent deflagration flames may generate high pressure pulses, temperature peaks, shock waves and large pressure gradients which could severely damage specific containment components, internal walls and/or safety equipment. The evaluation of such loads requires validated codes which can be used with a high level of confidence. Currently, turbulence and steam effect on flame acceleration, flame deceleration and flame quenching mechanisms are not well reproduced by combustion models usually implemented in safety tools and further model enhancement and validation are still needed. For this purpose, two hydrogen deflagration benchmark exercises have been organised in the framework of the SARNET network. The first benchmark was focused on turbulence effect on flame propagation. For this purpose, three tests performed in the ENACCEF facility were considered. They concern vertical flame propagation in an initially homogenous mixture with 13 vol.% hydrogen content and different geometrical configurations. Three blockage ratios of 0, 0.33 and 0.6 were considered to generate different levels of turbulence. The second benchmark objective was the investigation of the diluting effect on flame propagation. Thus, three tests performed in the ENACCEF facility using the same blockage ratio of 0.63 and three different initial gas compositions (with 10, 20 and 30 vol.% diluents) have been considered. Since ENACCEF runs at ambient temperature, a surrogate to steam was used consisting of a mixture of 0.6He + 0.4CO 2 on molar basis. This paper aims to present the benchmarks conclusions regarding the ability of LP and CFD combustion models to predict the effect of turbulence and diluent on flame propagation.
add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.anucene.2014.07.012&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu24 citations 24 popularity Top 10% influence Top 10% impulse Top 10% Powered by BIP!
more_vert add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.anucene.2014.07.012&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Preprint 2022Embargo end date: 01 Jan 2020 United KingdomPublisher:Elsevier BV Funded by:EC | ReUseHeatEC| ReUseHeatAuthors: Volodina, Victoria; Wheatcroft, Edward; Wynn, Henry;District heating is a network of pipes through which heat is delivered from a centralised source. It is expected to play an important role in the decarbonisation of the energy sector in the coming years. In district heating, heat is traditionally generated through fossil fuels, often with combined heat and power (CHP) units. However, increasingly, waste heat is being used as a low carbon alternative, either directly or, for low temperature sources, via a heat pump. The design of district heating often has competing objectives: the need for inexpensive energy and meeting low carbon targets. In addition, the planning of district heating schemes is subject to multiple sources of uncertainty such as variability in heat demand and energy prices. This paper proposes a decision support tool to analyse and compare system designs for district heating under uncertainty using stochastic ordering (dominance). Contrary to traditional uncertainty metrics that provide statistical summaries and impose total ordering, stochastic ordering is a partial ordering and operates with full probability distributions. In our analysis, we apply the orderings in the mean and dispersion to the waste heat recovery problem in Brunswick, Germany.
Sustainable Energy G... arrow_drop_down Sustainable Energy Grids and NetworksArticle . 2022 . Peer-reviewedLicense: CC BYData sources: Crossrefhttps://dx.doi.org/10.48550/ar...Article . 2020License: arXiv Non-Exclusive DistributionData sources: DataciteSustainable Energy Grids and NetworksArticle . 2022 . Peer-reviewedData sources: European Union Open Data Portaladd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.segan.2022.100634&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess RoutesGreen hybrid 4 citations 4 popularity Top 10% influence Average impulse Average Powered by BIP!
more_vert Sustainable Energy G... arrow_drop_down Sustainable Energy Grids and NetworksArticle . 2022 . Peer-reviewedLicense: CC BYData sources: Crossrefhttps://dx.doi.org/10.48550/ar...Article . 2020License: arXiv Non-Exclusive DistributionData sources: DataciteSustainable Energy Grids and NetworksArticle . 2022 . Peer-reviewedData sources: European Union Open Data Portaladd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.segan.2022.100634&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Journal , Other literature type 2017Publisher:MDPI AG Dawit Guta; Jose Jara; Narayan Adhikari; Qiu Chen; Varun Gaur; Alisher Mirzabaev;Access to reliable and affordable energy is vital for sustainable development. In the off-grid areas of developing countries, decentralized energy solutions have received increasing attention due to their contributions to reducing poverty. However, most of the rural population in many developing countries still has little or no access to modern energy technologies. This paper assesses the factors that determine the successes and failures of decentralized energy solutions based on local harmonized case studies from heterogeneous contexts from Asia, sub-Saharan Africa, and South America. The case studies were analyzed through the coupled lenses of energy transition and the Water–Energy–Food Security (WEF) Nexus. The findings indicate that access to modern decentralized energy solutions has not resulted in complete energy transitions due to various tradeoffs with the other domains of the WEF Nexus. On the other hand, the case studies point at the potential for improvements in food security, incomes, health, the empowerment of women, and resource conservation when synergies between decentralized energy solutions and other components of the WEF Nexus are present.
Resources arrow_drop_down ResourcesOther literature type . 2017License: CC BYFull-Text: http://www.mdpi.com/2079-9276/6/3/24/pdfData sources: Multidisciplinary Digital Publishing Instituteadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.3390/resources6030024&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess Routesgold 35 citations 35 popularity Top 10% influence Top 10% impulse Top 10% Powered by BIP!
more_vert Resources arrow_drop_down ResourcesOther literature type . 2017License: CC BYFull-Text: http://www.mdpi.com/2079-9276/6/3/24/pdfData sources: Multidisciplinary Digital Publishing Instituteadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.3390/resources6030024&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Other literature type 2023Publisher:MDPI AG Publicly fundedFunded by:EC | SCOREEC| SCOREAuthors: Tasneem Ahmed; Leo Creedon; Salem Gharbia;Unequivocal change in the climate system has put coastal regions around the world at increasing risk from climate-related hazards. Monitoring the coast is often difficult and expensive, resulting in sparse monitoring equipment lacking in sufficient temporal and spatial coverage. Thus, low-cost methods to monitor the coast at finer temporal and spatial resolution are imperative for climate resilience along the world’s coasts. Exploiting such low-cost methods for the development of early warning support could be invaluable to coastal settlements. This paper aims to provide the most up-to-date low-cost techniques developed and used in the last decade for monitoring coastal hazards and their forcing agents via systematic review of the peer-reviewed literature in three scientific databases: Scopus, Web of Science and ScienceDirect. A total of 60 papers retrieved from these databases through the preferred reporting items for systematic reviews and meta-analyses (PRISMA) protocol were analysed in detail to yield different categories of low-cost sensors. These sensors span the entire domain for monitoring coastal hazards, as they focus on monitoring coastal zone characteristics (e.g., topography), forcing agents (e.g., water levels), and the hazards themselves (e.g., coastal flooding). It was found from the meta-analysis of the retrieved papers that terrestrial photogrammetry, followed by aerial photogrammetry, was the most widely used technique for monitoring different coastal hazards, mainly coastal erosion and shoreline change. Different monitoring techniques are available to monitor the same hazard/forcing agent, for instance, unmanned aerial vehicles (UAVs), time-lapse cameras, and wireless sensor networks (WSNs) for monitoring coastal morphological changes such as beach erosion, creating opportunities to not only select but also combine different techniques to meet specific monitoring objectives. The sensors considered in this paper are useful for monitoring the most pressing challenges in coastal zones due to the changing climate. Such a review could be extended to encompass more sensors and variables in the future due to the systematic approach of this review. This study is the first to systematically review a wide range of low-cost sensors available for the monitoring of coastal zones in the context of changing climate and is expected to benefit coastal researchers and managers to choose suitable low-cost sensors to meet their desired objectives for the regular monitoring of the coast to increase climate resilience.
Sensors arrow_drop_down SensorsArticleLicense: CC BYFull-Text: https://www.mdpi.com/1424-8220/23/3/1717/pdfData sources: Sygmaadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.3390/s23031717&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess RoutesGreen gold 7 citations 7 popularity Top 10% influence Average impulse Top 10% Powered by BIP!
visibility 5visibility views 5 download downloads 8 Powered bymore_vert Sensors arrow_drop_down SensorsArticleLicense: CC BYFull-Text: https://www.mdpi.com/1424-8220/23/3/1717/pdfData sources: Sygmaadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.3390/s23031717&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Project deliverable , Other literature type 2023Publisher:Zenodo Funded by:EC | ePANACEAEC| ePANACEAAuthors: Andreas Androutsopoulos; Maria Bololia; Elpida Polychroni;The EU has set clear targets regarding energy conservation of buildings and heavily supports activities towards achieving these targets on a European scale. The Green Deal, renovation wave, Energy Performance of Buildings Directive (EPBD) and Energy Efficiency Directive (EED) are some examples of EU's actions. For more than a decade, Energy Performance Certificates provide detailed data about the current energy needs of a building/building unit as well as information about the building construction and systems. A Building Renovation Passport (BRP) has, on a European level lately, been conceived as a tool that can stimulate cost-effective renovation in the form of a long-term basis, step-by-step deep renovation roadmap following defined quality criteria, and outline energy renovation measures that will improve the energy performance of the building. A Digital Building Logbook (DBL) is another tool that can serve as an archive where all building information can be stored and continuously updated. In this way, a full record of the building history will be electronically available with data regarding construction plans and permits, maintenance and system replacement activities, energy and heat consumption and production, etc. Building Renovation Passports and the Digital Building Logbook are tools that can help in achieving energy efficiency in existing buildings and contribute to reaching the EU renovation wave goals. The objective of this report is to investigate how the current EPC schemes best make the link towards the BRP and the DBL to further incentivise and stimulate cost-effective deep energy renovations of buildings across Europe. Three surveys were carried out to collect relevant information about the current status of the EPC data records and to identify stakeholders' potential needs, perceptions, thoughts and expectations, regarding a future connection between the EPC and the BRP or DBL. These surveys were prepared in two forms: using an excel file format circulated via email, and through an online questionnaire. Their completion was carried out by 16 countries. Regarding the EPCs, the state or regional energy agencies are the owner of the EPC data records and make full use of them. Their current main usage is for statistical reasons in the majority of the countries and their access is publicly available in half of the responding countries. Many common data is stored in the EPC database which can be linked with other tools (half of the EPC databases are already linked with another source). Regarding the BRP, a review of existing European schemes showed that successful BRPs have combined the renovation advice with financial support, legal requirements and/or communication campaigns. An important factor of the BRP is that it should be issued by a qualified expert and should provide customised measures for the specific building together with the investment costs per renovation measure(s). The DBL analysis showed that it should provide access to building information and contribute to better decision-making for future interventions as well as operation, use and maintenance records. The building owner/user is proposed to have full access to the logbook and provide/input about energy bills and building plans/construction materials info. An important aspect is that every time the building undergoes intervention works, the DBL should be updated accordingly. The most important barrier is the lack of motivation to update the DBL contents followed by the absence of synergies and consistency with other tools. Another interesting finding is that both BRP and DBL should be fed automatically by EPC data without any user interference. There is a clear possible interconnection between EPC data and BRP and DBL future contents. In addition, BRP can be an instrument to increase the renovation rates and DBLs are necessary for the management of buildings' information. The linkage of EPC data and BRP and DBL can be strengthened by introducing BRP and DBL as voluntary schemes under national incentives and should be fully implemented once they have demonstrated acceptance by the stakeholders.
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You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.5281/zenodo.10265586&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess RoutesGreen 0 citations 0 popularity Average influence Average impulse Average Powered by BIP!
more_vert add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.5281/zenodo.10265586&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article 2022Publisher:Copernicus GmbH Funded by:EC | zEPHYREC| zEPHYRAuthors: Kartik Venkatraman; Trond-Ola Hågbo; Sophia Buckingham; Knut Erik Teigen Giljarhus;doi: 10.5194/wes-2021-142
Abstract. The assessment of wind conditions in complex terrain requires the use of Computational Fluid Dynamics (CFD) simulations incorporating an accurate parameterization of forest canopy effects and variable thermal stability effects. This study aims to investigate how incorporating the presence of trees can improve flow predictions. A three-dimensional steady Reynolds-averaged Navier-Stokes (RANS) equations model is set up using OpenFOAM to simulate the flow over a complex terrain site comprising two parallel ridges located near Perdigão, Portugal. A 7.5 km × 7.5 km terrain of the Perdigao site is constructed from elevation data centered around a 100 m met-mast located on the northeast ridge. A 30-min averaged stationary period corresponding to near-neutral conditions on a single met-mast tower is simulated. The impact of incorporating different source terms is studied such as forest canopy, Coriolis forces as well as also buoyancy forces. The prediction capability of the models is analyzed for different groups of towers on the South-West ridge, inside the valley, and on the North-East ridge based on the flow topology. The inclusion of a canopy model is shown to improve predictions close to the ground for most of the towers, while reducing prediction accuracy on top of the ridges, illustrating the need to represent terrain heterogeneity.
https://doi.org/10.5... arrow_drop_down https://doi.org/10.5194/wes-20...Article . 2022 . Peer-reviewedLicense: CC BYData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.5194/wes-2021-142&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess Routeshybrid 0 citations 0 popularity Average influence Average impulse Average Powered by BIP!
more_vert https://doi.org/10.5... arrow_drop_down https://doi.org/10.5194/wes-20...Article . 2022 . Peer-reviewedLicense: CC BYData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.5194/wes-2021-142&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Journal 2017 United KingdomPublisher:Elsevier BV Funded by:UKRI | Cretaceous-Paleocene-Eoce..., EC | TGRES, UKRI | The Descent into the Iceh... +2 projectsUKRI| Cretaceous-Paleocene-Eocene: Exploring Climate and Climate Sensitivity ,EC| TGRES ,UKRI| The Descent into the Icehouse ,UKRI| Terrestrial methane cycling during Paleogene greenhouse climates ,UKRI| Cretaceous-Paleocene-Eocene: Exploring Climate and Climate SensitivityInglis, Gordon N.; Collinson, Margaret E.; Riegel, Walter; Wilde, Volker; Farnsworth, Alexander; Lunt, Daniel J.; Valdes, Paul; Robson, Brittany E.; Scott, Andrew C.; Lenz, Olaf K.; Naafs, B. David A.; Pancost, Richard D.;Abstract Branched glycerol dialkyl glycerol tetraethers (brGDGTs) are increasingly used to reconstruct mean annual air temperature (MAAT) during the early Paleogene. However, the application of this proxy in coal deposits is limited and brGDGTs have only been detected in immature coals (i.e. lignites). Using samples recovered from Schoningen, Germany (∼48°N palaeolatitude), we provide the first detailed study into the occurrence and distribution of brGDGTs through a sequence of early Eocene lignites and associated interbeds. BrGDGTs are abundant and present in every sample. In comparison to modern studies, changes in vegetation type do not appear to significantly impact brGDGT distributions; however, there are subtle differences between lignites – representing peat-forming environments – and siliciclastic nearshore marine interbed depositional environments. Using the most recent brGDGT temperature calibration (MATmr) developed for soils, we generate the first continental temperature record from central-western continental Europe through the early Eocene. Lignite-derived MAAT estimates range from 23 to 26 °C while those derived from the nearshore marine interbeds exceed 20 °C. These estimates are consistent with other mid-latitude environments and model simulations, indicating enhanced mid-latitude, early Eocene warmth. In the basal part of the section studied, warming is recorded in both the lignites (∼2 °C) and nearshore marine interbeds (∼2–3 °C). This culminates in a long-term temperature maximum, likely including the Early Eocene Climatic Optimum (EECO). Although this long-term warming trend is relatively well established in the marine realm, it has rarely been shown in terrestrial settings. Using a suite of model simulations we show that the magnitude of warming at Schoningen is broadly consistent with a doubling of CO2, in agreement with late Paleocene and early Eocene pCO2 estimates.
e-Prints Soton arrow_drop_down e-Prints SotonArticle . 2017License: CC BY NC NDData sources: Bielefeld Academic Search Engine (BASE)Earth and Planetary Science LettersArticle . 2017 . Peer-reviewedLicense: CC BY NC NDData sources: CrossrefEarth and Planetary Science LettersArticle . 2017License: CC BY NC NDData sources: BASE (Open Access Aggregator)Fachrepositorium LebenswissenschaftenArticle . 2016License: CC BY NC NDData sources: Fachrepositorium LebenswissenschaftenUniversity of Bristol: Bristol ResearchArticle . 2017Data sources: Bielefeld Academic Search Engine (BASE)http://dx.doi.org/10.1016/j.ep...Article . Peer-reviewedData sources: European Union Open Data Portaladd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.epsl.2016.12.009&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess RoutesGreen hybrid 48 citations 48 popularity Top 10% influence Top 10% impulse Top 1% Powered by BIP!
more_vert e-Prints Soton arrow_drop_down e-Prints SotonArticle . 2017License: CC BY NC NDData sources: Bielefeld Academic Search Engine (BASE)Earth and Planetary Science LettersArticle . 2017 . Peer-reviewedLicense: CC BY NC NDData sources: CrossrefEarth and Planetary Science LettersArticle . 2017License: CC BY NC NDData sources: BASE (Open Access Aggregator)Fachrepositorium LebenswissenschaftenArticle . 2016License: CC BY NC NDData sources: Fachrepositorium LebenswissenschaftenUniversity of Bristol: Bristol ResearchArticle . 2017Data sources: Bielefeld Academic Search Engine (BASE)http://dx.doi.org/10.1016/j.ep...Article . Peer-reviewedData sources: European Union Open Data Portaladd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.epsl.2016.12.009&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Journal , Other literature type 2020Publisher:MDPI AG Funded by:EC | FAirWAYEC| FAirWAYAuthors: Klages, Susanne; Heidecke, Claudia; Osterburg, Bernhard;doi: 10.3390/w12061519
The hot summer of 2018 posed many challenges with regard to water shortages and yield losses, especially for agricultural production. These agricultural impacts might further pose consequent threats for the environment. In this paper, we deduce the impact of droughts on agricultural land management and on water quality owing to nitrate pollution. Using national statistics, we calculate a Germany-wide soil surface nitrogen budget for 2018 and deduce the additional N surplus owing to the dry weather conditions. Using a model farm approach, we compare fertilization practices and legal restrictions for arable and pig breeding farms. The results show that, nationwide, at least 464 kt of nitrogen were not transferred to plant biomass in 2018, which equals an additional average nitrogen surplus of 30 kg/ha. The surplus would even have amounted to 43 kg/ha, if farmers had continued their fertilization practice from preceding years, but German farmers applied 161 kt less nitrogen in 2018 than in the year before, presumably as a result of the new implications of the Nitrates Directive, and, especially on grassland, owing to the drought. As nitrogen surplus is regarded as an “agri-drinking water indicator” (ADWI), an increase of the surplus entails water pollution with nitrates. The examples of the model farms show that fertilization regimes with high shares of organic fertilizers produce higher nitrogen surpluses. Owing to the elevated concentrations on residual nitrogen in soils, the fertilization needs of crops in spring 2019 were less pronounced than in preceding years. Thus, the quantity of the continuously produced manure in livestock farms puts additional pressure on existing storage capacities. This may particularly be the case in the hot-spot regions of animal breeding in the north-west of Germany, where manure production, biogas plants, and manure imports are accumulating. The paper concludes that water shortages under climate change not only impact agricultural production and yields, but also place further challenges and threats to nutrient management and the environment. The paper discusses preventive and emergency management options for agriculture to support farmers in extremely dry and hot conditions.
Water arrow_drop_down WaterOther literature type . 2020License: CC BYFull-Text: http://www.mdpi.com/2073-4441/12/6/1519/pdfData sources: Multidisciplinary Digital Publishing InstituteWaterArticleLicense: CC BYFull-Text: https://www.mdpi.com/2073-4441/12/6/1519/pdfData sources: Sygmaadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.3390/w12061519&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess Routesgold 24 citations 24 popularity Top 10% influence Top 10% impulse Top 10% Powered by BIP!
more_vert Water arrow_drop_down WaterOther literature type . 2020License: CC BYFull-Text: http://www.mdpi.com/2073-4441/12/6/1519/pdfData sources: Multidisciplinary Digital Publishing InstituteWaterArticleLicense: CC BYFull-Text: https://www.mdpi.com/2073-4441/12/6/1519/pdfData sources: Sygmaadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.3390/w12061519&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Other literature type , Journal 2013Embargo end date: 01 Jan 2013 SwitzerlandPublisher:Copernicus GmbH Authors: Jannis Epting; Falk Händel; Falk Händel; Peter Huggenberger;Abstract. This study presents the development of tools for the sustainable thermal management of a shallow unconsolidated urban groundwater body in the city of Basel (Switzerland). The concept of the investigations is based on (1) a characterization of the present thermal state of the urban groundwater body, and (2) the evaluation of potential mitigation measures for the future thermal management of specific regions within the groundwater body. The investigations focus on thermal processes down-gradient of thermal groundwater use, effects of heated buildings in the subsurface as well as the thermal influence of river–groundwater interaction. Investigation methods include (1) short- and long-term data analysis, (2) high-resolution multilevel groundwater temperature monitoring, as well as (3) 3-D numerical groundwater flow and heat transport modeling and scenario development. The combination of these methods allows for the quantifying of the thermal influences on the investigated urban groundwater body, including the influences of thermal groundwater use and heated subsurface constructions. Subsequently, first implications for management strategies are discussed, including minimizing further groundwater temperature increase, targeting "potential natural" groundwater temperatures for specific aquifer regions and exploiting the thermal potential.
University of Basel:... arrow_drop_down University of Basel: edocArticle . 2013License: CC BYData sources: Bielefeld Academic Search Engine (BASE)Hydrology and Earth System Sciences (HESS)Article . 2013 . Peer-reviewedLicense: CC BYData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.5194/hess-17-1851-2013&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess RoutesGreen gold 88 citations 88 popularity Top 10% influence Top 10% impulse Top 10% Powered by BIP!
more_vert University of Basel:... arrow_drop_down University of Basel: edocArticle . 2013License: CC BYData sources: Bielefeld Academic Search Engine (BASE)Hydrology and Earth System Sciences (HESS)Article . 2013 . Peer-reviewedLicense: CC BYData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.5194/hess-17-1851-2013&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Other literature type 2023 SpainPublisher:Ovid Technologies (Wolters Kluwer Health) Funded by:EC | NextGen IO, NIH | Liver-enriched Transcript...EC| NextGen IO ,NIH| Liver-enriched Transcription Factors as Prognostic Markers and Therapeutic Targets in Alcoholic HepatitisAuthors: Goikoetxea-Usandizaga, Naroa; Bravo, Miren; Egia-Mendikute, Leire; Abecia, Leticia; +38 AuthorsGoikoetxea-Usandizaga, Naroa; Bravo, Miren; Egia-Mendikute, Leire; Abecia, Leticia; Serrano-Maciá, Marina; Urdinguio, Rocío G.; Clos-García, Marc; Rodríguez-Agudo, Rubén; Araujo-Legido, Raquel; López-Bermudo, Lucía; Delgado, Teresa C.; Lachiondo-Ortega, Sofía; González-Recio, Irene; Gil-Pitarch, Clàudia; Peña-Cearra, Ainize; Simón, Jorge; Benedé-Ubieto, Raquel; Ariño, Silvia; Herranz, Jose M.; Azkargorta, Mikel; Salazar-Bermeo, Julio; Martí, Nuria; Varela-Rey, Marta; Falcón-Pérez, Juan M.; Lorenzo, Óscar; Nogueiras, Rubén; Elortza, Félix; Nevzorova, Yulia; Cubero, Francisco J.; Saura, Domingo; Martínez-Cruz, Luis Alfonso; Sabio, Guadalupe; Palazón, Asís; Palazón, Asís; Sancho-Bru, Pau; Elguezabal, Natalia; Fraga, Mario F.; Ávila, Matías A.; Bataller, Ramón; Marín, José J. G.; Martín, Franz; Martínez-Chantar, María Luz;Background and Aims: Alcohol-associated liver disease (ALD) accounts for 70% of liver-related deaths in Europe, with no effective approved therapies. Although mitochondrial dysfunction is one of the earliest manifestations of alcohol-induced injury, restoring mitochondrial activity remains a problematic strategy due to oxidative stress. Here, we identify methylation-controlled J protein (MCJ) as a mediator for ALD progression and hypothesize that targeting MCJ may help in recovering mitochondrial fitness without collateral oxidative damage. Approach and Results: C57BL/6 mice [wild-type (Wt)] Mcj knockout and Mcj liver-specific silencing (MCJ-LSS) underwent the NIAAA dietary protocol (Lieber-DeCarli diet containing 5% (vol/vol) ethanol for 10 days, plus a single binge ethanol feeding at day 11). To evaluate the impact of a restored mitochondrial activity in ALD, the liver, gut, and pancreas were characterized, focusing on lipid metabolism, glucose homeostasis, intestinal permeability, and microbiota composition. MCJ, a protein acting as an endogenous negative regulator of mitochondrial respiration, is downregulated in the early stages of ALD and increases with the severity of the disease. Whole-body deficiency of MCJ is detrimental during ALD because it exacerbates the systemic effects of alcohol abuse through altered intestinal permeability, increased endotoxemia, and dysregulation of pancreatic function, which overall worsens liver injury. On the other hand, liver-specific Mcj silencing prevents main ALD hallmarks, that is, mitochondrial dysfunction, steatosis, inflammation, and oxidative stress, as it restores the NAD+/NADH ratio and SIRT1 function, hence preventing de novo lipogenesis and improving lipid oxidation. Conclusions: Improving mitochondrial respiration by liver-specific Mcj silencing might become a novel therapeutic approach for treating ALD.
Hepatology arrow_drop_down HepatologyArticleLicense: http://creativecommons.org/licenses/by-nc-nd/4.0/ http://creativecommons.org/licenses/by-nc-nd/4.0/Data sources: SygmaHepatologyArticle . 2023 . Peer-reviewedLicense: http://creativecommons.org/licenses/by-nc-nd/4.0/ http://creativecommons.org/licenses/by-nc-nd/4.0/Data sources: CrossrefRecolector de Ciencia Abierta, RECOLECTAArticle . 2023Data sources: Recolector de Ciencia Abierta, RECOLECTARecolector de Ciencia Abierta, RECOLECTAArticle . 2023License: CC BY NC NDData sources: Recolector de Ciencia Abierta, RECOLECTAadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1097/hep.0000000000000303&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess RoutesGreen hybrid 12 citations 12 popularity Top 10% influence Average impulse Top 10% Powered by BIP!
visibility 49visibility views 49 download downloads 118 Powered bymore_vert Hepatology arrow_drop_down HepatologyArticleLicense: http://creativecommons.org/licenses/by-nc-nd/4.0/ http://creativecommons.org/licenses/by-nc-nd/4.0/Data sources: SygmaHepatologyArticle . 2023 . Peer-reviewedLicense: http://creativecommons.org/licenses/by-nc-nd/4.0/ http://creativecommons.org/licenses/by-nc-nd/4.0/Data sources: CrossrefRecolector de Ciencia Abierta, RECOLECTAArticle . 2023Data sources: Recolector de Ciencia Abierta, RECOLECTARecolector de Ciencia Abierta, RECOLECTAArticle . 2023License: CC BY NC NDData sources: Recolector de Ciencia Abierta, RECOLECTAadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1097/hep.0000000000000303&type=result"></script>'); --> </script>
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