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We present the architecture and design of the IANOS scheduling framework. The goal of the new Grid scheduling system is to provide a general job submission framework allowing optimal positioning and scheduling of HPCN applications. The scheduling algorithms used to calculate best-suited resources are based on an objective cost function that exploits information on the parameterization of applications and resources. This standard-based, interoperable scheduling framework comprises four general web services and three modules. The middleware is complemented with one client and one admin console. The implementation is based on proposed Grid and Web services standards (WSRF, WS-Agreement, JSDL, and GLUE). It is agnostic to a specific Grid middleware. The beta version of IANOS has been tested and integrated with UNICORE. The validation of IANOS is in progress by running different types of HPCN applications on a large-scale Grid testbed.

If femoral blood is not available at autopsy, toxicological analyses, in particular blood ethanol measurements, are carried out on cardiac blood. This is known to be subject to major redistribution. We aimed to determine whether subclavian blood can be equated with a peripheral blood sample and could be used if femoral blood is not available. The study was based on 50 medicolegal autopsies in which we compared ethanol concentrations between subclavian blood, the different heart blood compartments (right and left cardiac blood), and femoral blood. Mechanisms that could lead to variations in concentration, i.e., postmortem redistribution and/or endogenous production, were also taken into account in interpreting the results. Ethanol concentrations were determined by headspace gas chromatography with a flame ionization detector. In each case, we recorded the circumstances of death, resuscitation attempts if any, degree of putrefaction, chest or abdominal trauma, and/or inhalation of gastric fluid in the airways. Ethanol concentrations in subclavian blood were found to be close to those in peripheral blood (p = 0.948) and were not influenced by the degree of putrefaction (r = 0.017, p = 0.904), gastric ethanol concentration (r = -0.011, p = 0.940), inhalation of gastric contents in the airways (p = 0.461), or cardiac resuscitation attempts (p = 0.368). We discuss the possible explanations for these findings and stress the value of sampling subclavian blood when femoral blood is not obtainable at autopsy.

This deliverable includes the methodology in EnergyPROSPECTS for an in-depth study of energy citizenship. It features the criteria used for selecting the cases for indepth study, the list of cases selected for in-depth study as well as key research foci and empirical research questions.

The rapidly changing climate presents unprecedented challenges, especially in permafrost regions, where its thawing directly affects houses, mines, roads, pipelines, airport runways, and rail tracks. Monitoring the dynamics of ground ice in permafrost landscapes is essential for assessing geohazards and adapting infrastructure to changing conditions. This abstract presents a new initiative utilizing cosmic neutrons metrology for permafrost studies, specifically focusing on ground-ice content monitoring. Traditional methods for assessing ground-ice content in permafrost regions involve labor-intensive surveys and analysis of geomorphological features. However, these approaches are often limited in spatial coverage and may not capture the full extent of ground-ice distribution. In response to these challenges, we propose leveraging cosmic neutrons as a non-invasive and scalable method for assessing ground-ice content. Cosmic neutrons naturally penetrate the Earth's surface and interact with hydrogen atoms in the soil, including those bound in water molecules. By measuring the cosmic neutron albedo, which is the flux of epithermal neutrons that are partially thermalized in the ground, we can infer the presence and distribution of ground ice. This approach builds upon established techniques used for soil moisture monitoring, adapting them for permafrost studies. In that regard, we conducted Monte Carlo simulations of cosmic neutron transport and interaction with modeled ground to investigate the feasibility of using cosmic neutrons for ground-ice content monitoring. Our simulations considered various ground compositions and ice concentrations to assess the sensitivity of cosmic neutron measurements to ground-ice content. The results of our simulations provide promising proof-of-concept for the proposed method, demonstrating its potential for accurately estimating ground-ice content in permafrost landscapes. Additionally, we are developing at DOSEO (CEA – Saclay, France) thermal over fast neutron reference fields that could be used to test, characterize, and calibrate detectors specifically for the presented application. The proposed method offers several advantages. Firstly, it provides measurements on a metric scale (~10m wide on ~1m depth), effectively balancing local detail with regional coverage, thus making it well-suited for mapping geohazards on a kilometric scale. Additionally, cosmic neutrons albedo measurements is non-destructive and non-invasive and can be applied across diverse permafrost landscapes, offering valuable insights into ground-ice dynamics. Moreover, mapping ground-ice content is feasible through the flexible deployment of neutron detectors. These detectors can either be moved around the study area to gather spatially distributed measurements or installed as fixed monitoring stations, enabling continuous observation of ground-ice dynamics across different seasons and over time. Integration of data from cosmic neutrons albedo measurements into Geographic Information System (GIS) applications enhances the ability to map geohazards and predict future changes in permafrost landscape stability. By combining information on ground-ice content with elevation, drainage patterns, periglacial features, and infrastructure, a better understanding of the interactions between climate change and geohazards in permafrost regions is achievable.In conclusion, cosmic neutrons metrology offers a promising approach for monitoring ground-ice content in permafrost landscapes. By advancing our understanding of permafrost dynamics, this initiative contributes to the broader goals of cryosphere monitoring and sustainable development.

Abstract In this paper, a general mathematical model for the dynamic simulation of a single-effect LiBr/water absorption chiller is presented. The model is based on mass and energy balances applied to the internal components of the machine, and it accounts for the non-steady behaviour due to thermal and mass storage in the components. The validation of the mathematical model is performed through experimental data collected on a commercial small-capacity water-cooled unit. Due to the peculiar technology adopted in the real chiller, a special effort was made to identify the appropriate values of the main physical parameters. The validation of the model is based on the values of the water temperature at the outlet of the machine, as no measurement inside the machine was possible; anyway, a consistency analysis applied to the internal parameters is also presented. The agreement between experimental and simulated results is very good, both on a daily and on a seasonal basis.

In biomedical scientific investigations, expositions of findings are conceptually simplest when they comprise comparisons of discrete groups of individuals or involve discrete features or characteristics of individuals. But the descriptive benefits of categorization become outweighed by their limitations in studies involving dose-response relationships, as in many teratogenic and environmental exposure studies. This article addresses a pair of categorization issues concerning the effects of prenatal alcohol exposure that have important public health consequences: the labeling of individuals as fetal alcohol syndrome (FAS) versus fetal alcohol effects (FAE) or alcohol-related neurodevelopmental disorder (ARND), and the categorization of prenatal exposure dose by thresholds. We present data showing that patients with FAS and others with FAE do not have meaningfully different behavioral performance, standardized scores of IQ, arithmetic and adaptive behavior, or secondary disabilities. Similarly overlapping distributions on measures of executive functioning offer a basis for identifying alcohol-affected individuals in a manner that does not simply reflect IQ deficits. At the other end of the teratological continuum, we turn to the reporting of threshold effects in dose-response relationships. Here we illustrate the importance of multivariate analyses using data from the Seattle, Washington, longitudinal prospective study on alcohol and pregnancy. Relationships between many neurobehavioral outcomes and measures of prenatal alcohol exposure are monotone without threshold down to the lowest nonzero levels of exposure, a finding consistent with reports from animal studies. In sum, alcohol effects on the developing human brain appear to be a continuum without threshold when dose and behavioral effects are quantified appropriately.

Les conséquences du changement climatique sont particulièrement aiguës au Kenya, où 80 % des terres sont arides ou semi-arides. Quelle perspective critique et constructive le concept d’habitabilité peut-il offrir dans ce contexte ? Fondé sur un travail de terrain réalisé au Kenya en 2022 et 2023, cet article entend affiner une définition in situ de l’habitabilité, en utilisant exclusivement des données qualitatives issues de deux phases de recherche, complétées par des exercices de vidéo-cartographie. Loin de proposer une lecture positiviste de l’habitabilité, portée par une conception exclusivement mécanique et linéaire des dynamiques de mobilité, cette étude propose de mieux relier l’habitabilité aux pratiques quotidiennes, aux habitudes, aux solidarités, voire aux résistances qui constituent la vie ordinaire des habitants des communautés et des personnes déplacées. L’habitabilité se situerait alors au cœur de l’intrication entre socialité et spatialité, entre social et biologique, qui définit – selon Stanley Cavell – la forme de vie humaine. The consequences of climate change are particularly acute in Kenya, where 80% of the land is arid or semi-arid. What critical and constructive perspective can the concept of habitability offer in this context? Based on fieldwork carried out in Kenya in 2022 and 2023, this article aims to refine an in-situ definition of habitability, using exclusively qualitative data from two research phases, supplemented by video-mapping exercises. Far from proposing a positivist reading of habitability, driven by an exclusively mechanical and linear conception of mobility dynamics, this study proposes to better link habitability to the daily practices, habits, solidarities and even resistances that make up the ordinary lives of community dwellers and displaced persons. Habitability would then lie at the heart of the intricacy between sociality and spatiality, between the social and the biological, which defines – according to Stanley Cavell – “the human form of life.”