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  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Hugh Montgomery; D. Pencheon; J. R. Sneyd;
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Anaesthesiaarrow_drop_down
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Anaesthesia
    Article
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    image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
    Anaesthesia
    Article . 2010 . Peer-reviewed
    License: Wiley Online Library User Agreement
    Data sources: Crossref
    Anaesthesia
    Other literature type . 2010
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      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Anaesthesiaarrow_drop_down
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
      Anaesthesia
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      image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
      Anaesthesia
      Article . 2010 . Peer-reviewed
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      Anaesthesia
      Other literature type . 2010
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  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Hugh Montgomery; Sabaratnam Arulkumaran; David McCoy; Fiona Godlee;

    The IPCC report shows the need for “radical and transformative change” Next week the Intergovernmental Panel on Climate Change (IPCC) will publish its report on the impacts of global warming. Building on its recent update of the physical science of global warming,1 the IPCC’s new report should leave the world in no doubt about the scale and immediacy of the threat to human survival, health, and wellbeing. The IPCC has already concluded that it is “virtually certain that human influence has warmed the global climate system” and that it is “extremely likely that more than half of the observed increase in global average surface temperature from 1951 to 2010” is anthropogenic.1 Its new report outlines the future threats of further global warming: increased scarcity of food and fresh water; extreme weather events; rise in sea level; loss of biodiversity; areas becoming uninhabitable; and mass human migration, conflict and violence. Leaked drafts talk of hundreds of millions displaced in a little over 80 years. This month, the American Association for the Advancement of Science (AAAS) added its voice: “the well being of people of all nations [is] at risk.”2 Such comments reaffirm the conclusions of …

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ BMJarrow_drop_down
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    BMJ
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    BMJ
    Article . 2014 . Peer-reviewed
    Data sources: Crossref
    BMJ
    Other literature type . 2014
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      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ BMJarrow_drop_down
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
      BMJ
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      BMJ
      Article . 2014 . Peer-reviewed
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      BMJ
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  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Nick Watts; W. Neil Adger; Sonja Ayeb‐Karlsson; Yuqi Bai; +44 Authors

    The Lancet Countdown : le suivi des progrès en matière de santé et de changement climatique est une collaboration de recherche internationale et multidisciplinaire entre des établissements universitaires et des praticiens du monde entier. Il fait suite aux travaux de la Commission Lancet de 2015, qui a conclu que la réponse au changement climatique pourrait être « la plus grande opportunité de santé mondiale du XXIe siècle ». Le compte à rebours du Lancet vise à suivre les impacts sur la santé des risques climatiques ; la résilience et l'adaptation en matière de santé ; les co-bénéfices pour la santé de l'atténuation du changement climatique ; l'économie et la finance ; et l'engagement politique et plus large. Ces domaines d'intervention forment les cinq groupes de travail thématiques du Lancet Countdown et représentent différents aspects de l'association complexe entre la santé et le changement climatique. Ces groupes thématiques fourniront des indicateurs pour une vue d'ensemble mondiale de la santé et du changement climatique ; des études de cas nationales mettant en évidence les pays qui ouvrent la voie ou vont à l'encontre de la tendance ; et un engagement avec un éventail de parties prenantes. Le compte à rebours du Lancet vise finalement à rendre compte chaque année d'une série d'indicateurs dans ces cinq groupes de travail. Ce document décrit les indicateurs potentiels et les domaines d'indicateurs à suivre par la collaboration, avec des suggestions sur les méthodologies et les ensembles de données disponibles pour atteindre cet objectif. Les domaines d'indicateurs proposés doivent être affinés et marquent le début d'un processus de consultation en cours - de novembre 2016 au début de 2017 - pour développer ces domaines, identifier les domaines clés non couverts actuellement et modifier les indicateurs si nécessaire. Cette collaboration cherchera activement à s'engager dans les processus de suivi existants, tels que les objectifs de développement durable des Nations Unies et les profils de pays de l'OMS en matière de climat et de santé. Les indicateurs évolueront également au fil du temps grâce à une collaboration continue avec des experts et un éventail de parties prenantes, et dépendront de l'émergence de nouvelles preuves et connaissances. Au cours de ses travaux, le Lancet Countdown adoptera un processus collaboratif et itératif, qui vise à compléter les initiatives existantes, à accueillir l'engagement avec de nouveaux partenaires et à être ouvert au développement de nouveaux projets de recherche sur la santé et le changement climatique. The Lancet Countdown: tracking progress on health and climate change es una colaboración de investigación internacional y multidisciplinaria entre instituciones académicas y profesionales de todo el mundo. Sigue el trabajo de la Comisión Lancet de 2015, que concluyó que la respuesta al cambio climático podría ser "la mayor oportunidad de salud global del siglo XXI". The Lancet Countdown tiene como objetivo realizar un seguimiento de los impactos en la salud de los peligros climáticos; la resiliencia y la adaptación a la salud; los beneficios colaterales para la salud de la mitigación del cambio climático; la economía y las finanzas; y el compromiso político y más amplio. Estas áreas de enfoque forman los cinco grupos de trabajo temáticos de The Lancet Countdown y representan diferentes aspectos de la compleja asociación entre la salud y el cambio climático. Estos grupos temáticos proporcionarán indicadores para una visión global de la salud y el cambio climático; estudios de casos nacionales que destacan a los países que lideran el camino o van en contra de la tendencia; y el compromiso con una variedad de partes interesadas. En última instancia, The Lancet Countdown tiene como objetivo informar anualmente sobre una serie de indicadores en estos cinco grupos de trabajo. Este documento describe los posibles indicadores y dominios de indicadores a ser rastreados por la colaboración, con sugerencias sobre las metodologías y conjuntos de datos disponibles para lograr este fin. Los dominios de indicadores propuestos requieren un mayor refinamiento y marcan el comienzo de un proceso de consulta continuo, desde noviembre de 2016 hasta principios de 2017, para desarrollar estos dominios, identificar áreas clave que actualmente no están cubiertas y cambiar los indicadores cuando sea necesario. Esta colaboración buscará activamente involucrarse con los procesos de monitoreo existentes, como los Objetivos de Desarrollo Sostenible de la ONU y LOS perfiles climáticos y de salud de los países de la OMS. Los indicadores también evolucionarán con el tiempo a través de la colaboración continua con expertos y una variedad de partes interesadas, y dependerán de la aparición de nuevas pruebas y conocimientos. Durante el transcurso de su trabajo, The Lancet Countdown adoptará un proceso colaborativo e iterativo, que tiene como objetivo complementar las iniciativas existentes, dar la bienvenida al compromiso con nuevos socios y estar abierto al desarrollo de nuevos proyectos de investigación sobre salud y cambio climático. The Lancet Countdown: tracking progress on health and climate change is an international, multidisciplinary research collaboration between academic institutions and practitioners across the world. It follows on from the work of the 2015 Lancet Commission, which concluded that the response to climate change could be "the greatest global health opportunity of the 21st century". The Lancet Countdown aims to track the health impacts of climate hazards; health resilience and adaptation; health co-benefits of climate change mitigation; economics and finance; and political and broader engagement. These focus areas form the five thematic working groups of the Lancet Countdown and represent different aspects of the complex association between health and climate change. These thematic groups will provide indicators for a global overview of health and climate change; national case studies highlighting countries leading the way or going against the trend; and engagement with a range of stakeholders. The Lancet Countdown ultimately aims to report annually on a series of indicators across these five working groups. This paper outlines the potential indicators and indicator domains to be tracked by the collaboration, with suggestions on the methodologies and datasets available to achieve this end. The proposed indicator domains require further refinement, and mark the beginning of an ongoing consultation process-from November, 2016 to early 2017-to develop these domains, identify key areas not currently covered, and change indicators where necessary. This collaboration will actively seek to engage with existing monitoring processes, such as the UN Sustainable Development Goals and WHO's climate and health country profiles. The indicators will also evolve over time through ongoing collaboration with experts and a range of stakeholders, and be dependent on the emergence of new evidence and knowledge. During the course of its work, the Lancet Countdown will adopt a collaborative and iterative process, which aims to complement existing initiatives, welcome engagement with new partners, and be open to developing new research projects on health and climate change. العد التنازلي لمجلة لانسيت: تتبع التقدم المحرز في مجال الصحة وتغير المناخ هو تعاون بحثي دولي متعدد التخصصات بين المؤسسات الأكاديمية والممارسين في جميع أنحاء العالم. ويتبع ذلك عمل لجنة لانسيت لعام 2015، التي خلصت إلى أن الاستجابة لتغير المناخ يمكن أن تكون "أعظم فرصة صحية عالمية في القرن الحادي والعشرين". يهدف العد التنازلي لمجلة لانسيت إلى تتبع الآثار الصحية للمخاطر المناخية ؛ والمرونة الصحية والتكيف ؛ والفوائد الصحية المشتركة للتخفيف من آثار تغير المناخ ؛ والاقتصاد والتمويل ؛ والمشاركة السياسية والأوسع نطاقًا. تشكل مجالات التركيز هذه مجموعات العمل المواضيعية الخمسة للعد التنازلي لمجلة لانسيت وتمثل جوانب مختلفة من الارتباط المعقد بين الصحة وتغير المناخ. وستوفر هذه المجموعات المواضيعية مؤشرات لإلقاء نظرة عامة عالمية على الصحة وتغير المناخ ؛ ودراسات حالة وطنية تسلط الضوء على البلدان التي تقود الطريق أو تسير عكس الاتجاه ؛ والمشاركة مع مجموعة من أصحاب المصلحة. يهدف العد التنازلي لمجلة لانسيت في نهاية المطاف إلى تقديم تقرير سنوي عن سلسلة من المؤشرات عبر مجموعات العمل الخمس هذه. تحدد هذه الورقة المؤشرات المحتملة ومجالات المؤشرات التي سيتم تتبعها من خلال التعاون، مع اقتراحات حول المنهجيات ومجموعات البيانات المتاحة لتحقيق هذه الغاية. تتطلب مجالات المؤشرات المقترحة مزيدًا من التنقيح، وتمثل بداية عملية تشاور مستمرة - من نوفمبر 2016 إلى أوائل 2017 - لتطوير هذه المجالات، وتحديد المجالات الرئيسية غير المشمولة حاليًا، وتغيير المؤشرات عند الضرورة. سيسعى هذا التعاون بنشاط إلى المشاركة في عمليات الرصد القائمة، مثل أهداف الأمم المتحدة للتنمية المستدامة والملامح القطرية للمناخ والصحة لمنظمة الصحة العالمية. ستتطور المؤشرات أيضًا بمرور الوقت من خلال التعاون المستمر مع الخبراء ومجموعة من أصحاب المصلحة، وستعتمد على ظهور أدلة ومعارف جديدة. خلال عملها، سيعتمد العد التنازلي لمجلة لانسيت عملية تعاونية وتكرارية، تهدف إلى استكمال المبادرات الحالية، والترحيب بالمشاركة مع شركاء جدد، والانفتاح على تطوير مشاريع بحثية جديدة حول الصحة وتغير المناخ.

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ COREarrow_drop_down
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    The Lancet
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    UCL Discovery
    Article . 2016
    Data sources: UCL Discovery
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    The Lancet
    Article . 2017 . Peer-reviewed
    License: Elsevier TDM
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    https://dx.doi.org/10.60692/cz...
    Other literature type . 2017
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    https://dx.doi.org/10.60692/9b...
    Other literature type . 2017
    Data sources: Datacite
    The Lancet
    Article . 2018
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    Authors: Azhar Tarbhai; Angela S. McNelly; Angela S. McNelly; Angela S. McNelly; +17 Authors

    Acute skeletal muscle wasting in critical illness is associated with excess morbidity and mortality. Continuous feeding may suppress muscle protein synthesis as a result of the muscle-full effect, unlike intermittent feeding, which may ameliorate it.Does intermittent enteral feed decrease muscle wasting compared with continuous feed in critically ill patients?In a phase 2 interventional single-blinded randomized controlled trial, 121 mechanically ventilated adult patients with multiorgan failure were recruited following prospective informed consultee assent. They were randomized to the intervention group (intermittent enteral feeding from six 4-hourly feeds per 24 h, n = 62) or control group (standard continuous enteral feeding, n = 59). The primary outcome was 10-day loss of rectus femoris muscle cross-sectional area determined by ultrasound. Secondary outcomes included nutritional target achievements, plasma amino acid concentrations, glycemic control, and physical function milestones.Muscle loss was similar between arms (-1.1% [95% CI, -6.1% to -4.0%]; P = .676). More intermittently fed patients received 80% or more of target protein (OR, 1.52 [1.16-1.99]; P < .001) and energy (OR, 1.59 [1.21-2.08]; P = .001). Plasma branched-chain amino acid concentrations before and after feeds were similar between arms on trial day 1 (71 μM [44-98 μM]; P = .547) and trial day 10 (239 μM [33-444 μM]; P = .178). During the 10-day intervention period the coefficient of variation for glucose concentrations was higher with intermittent feed (17.84 [18.6-20.4]) vs continuous feed (12.98 [14.0-15.7]; P < .001). However, days with reported hypoglycemia and insulin usage were similar in both groups. Safety profiles, gastric intolerance, physical function milestones, and discharge destinations did not differ between groups.Intermittent feeding in early critical illness is not shown to preserve muscle mass in this trial despite resulting in a greater achievement of nutritional targets than continuous feeding. However, it is feasible and safe.ClinicalTrials.gov; No.: NCT02358512; URL: www.clinicaltrials.gov.

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    Authors: Hugh Montgomery;
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    Biofuel Research Journal
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  • Authors: Hugh Montgomery; Nick Watts; Anthony Costello;

    They need to use their ability to communicate bad news in a way that stimulates a positive response

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    Authors: Watts, N.; Adger, W.N.; Agnolucci, P.; Blackstock, J.; +41 Authors

    The 2015 Lancet Commission on Health and Climate Change has been formed to map out the impacts of climate change, and the necessary policy responses, in order to ensure the highest attainable stand ...

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    Authors: White S. M.; Shelton C. L.; Gelb A. W.; Lawson C.; +48 Authors

    SummaryThe Earth’s mean surface temperature is already approximately 1.1°C higher than pre‐industrial levels. Exceeding a mean 1.5°C rise by 2050 will make global adaptation to the consequences of climate change less possible. To protect public health, anaesthesia providers need to reduce the contribution their practice makes to global warming. We convened a Working Group of 45 anaesthesia providers with a recognised interest in sustainability, and used a three‐stage modified Delphi consensus process to agree on principles of environmentally sustainable anaesthesia that are achievable worldwide. The Working Group agreed on the following three important underlying statements: patient safety should not be compromised by sustainable anaesthetic practices; high‐, middle‐ and low‐income countries should support each other appropriately in delivering sustainable healthcare (including anaesthesia); and healthcare systems should be mandated to reduce their contribution to global warming. We set out seven fundamental principles to guide anaesthesia providers in the move to environmentally sustainable practice, including: choice of medications and equipment; minimising waste and overuse of resources; and addressing environmental sustainability in anaesthetists’ education, research, quality improvement and local healthcare leadership activities. These changes are achievable with minimal material resource and financial investment, and should undergo re‐evaluation and updates as better evidence is published. This paper discusses each principle individually, and directs readers towards further important references.

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    Anaesthesia
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    Authors: Romanello, Marina; McGushin, Alice; Di Napoli, Claudia; Drummond, Paul; +89 Authors

    The Lancet Countdown is an international collaboration that independently monitors the health consequences of a changing climate. Publishing updated, new, and improved indicators each year, the Lancet Countdown represents the consensus of leading researchers from 43 academic institutions and UN agencies. The 44 indicators of this report expose an unabated rise in the health impacts of climate change and the current health consequences of the delayed and inconsistent response of countries around the globe—providing a clear imperative for accelerated action that puts the health of people and planet above all else. The 2021 report coincides with the UN Framework Convention on Climate Change 26th Conference of the Parties (COP26), at which countries are facing pressure to realise the ambition of the Paris Agreement to keep the global average temperature rise to 1·5°C and to mobilise the financial resources required for all countries to have an effective climate response. These negotiations unfold in the context of the COVID-19 pandemic—a global health crisis that has claimed millions of lives, affected livelihoods and communities around the globe, and exposed deep fissures and inequities in the world’s capacity to cope with, and respond to, health emergencies. Yet, in its response to both crises, the world is faced with an unprecedented opportunity to ensure a healthy future for all. DEEPENING INEQUITIES IN A WARMING WORLD: Record temperatures in 2020 resulted in a new high of 3·1 billion more person-days of heatwave exposure among people older than 65 years and 626 million more person-days affecting children younger than 1 year, compared with the annual average for the 1986–2005 baseline (indicator 1.1.2). Looking to 2021, people older than 65 years or younger than 1 year, along with people facing social disadvantages, were the most affected by the record-breaking temperatures of over 40°C in the Pacific Northwest areas of the USA and Canada in June, 2021—an event that would have been almost impossible without human-caused climate change. Although the exact number will not be known for several months, hundreds of people have died prematurely from the heat. Furthermore, populations in countries with low and medium levels of UN-defined human development index (HDI) have had the biggest increase in heat vulnerability during the past 30 years, with risks to their health further exacerbated by the low availability of cooling mechanisms and urban green space (indicators 1.1.1, 2.3.2, and 2.3.3). Agricultural workers in countries with low and medium HDI were among the worst affected by exposure to extreme temperatures, bearing almost half of the 295 billion potential work hours lost due to heat in 2020 (indicator 1.1.4). These lost work hours could have devastating economic consequences to these already vulnerable workers—data in this year’s report shows that the average potential earnings lost in countries in the low HDI group were equivalent to 4–8% of the national gross domestic product (indicator 4.1.3). Through these effects, rising average temperatures, and altered rainfall patterns, climate change is beginning to reverse years of progress in tackling the food and water insecurity that still affects the most underserved populations around the world, denying them an essential aspect of good health. During any given month in 2020, up to 19% of the global land surface was affected by extreme drought; a value that had not exceeded 13% between 1950 and 1999 (indicator 1.2.2). In parallel with drought, warm temperatures are affecting the yield potential of the world’s major staple crops—a 6·0% reduction for maize; 3·0% for winter wheat; 5·4% for soybean; and 1·8% for rice in 2020, relative to 1981–2010 (indicator 1.4.1)—exposing the rising risk of food insecurity. Adding to these health hazards, the changing environmental conditions are also increasing the suitability for the transmission of many water-borne, air-borne, food-borne, and vector-borne pathogens. Although socioeconomic development, public health interventions, and advances in medicine have reduced the global burden of infectious disease transmission, climate change could undermine eradication efforts. The number of months with environmentally suitable conditions for the transmission of malaria (Plasmodium falciparum) rose by 39% from 1950–59 to 2010–19 in densely populated highland areas in the low HDI group, threatening highly disadvantaged populations who were comparatively safer from this disease than those in the lowland areas (indicator 1.3.1). The epidemic potential for dengue virus, Zika virus, and chikungunya virus, which currently primarily affect populations in central America, South America, the Caribbean, Africa, and south Asia, increased globally, with a basic reproductive rate increase of 13% for transmission by Aedes aegypti and 7% for transmission by Aedes albopictus compared with the 1950s. The biggest relative increase in basic reproductive rate of these arboviruses was seen in countries in the very high HDI group (indicator 1.3.1); however, people in the low HDI group are confronted with the highest vulnerability to these arboviruses (indicator 1.3.2). Similar findings are observed in the environmental suitability for Vibrio cholerae, a pathogen estimated to cause almost 100 000 deaths annually, particularly among populations with poor access to safe water and sanitation. Between 2003 and 2019, the coastal areas suitable for V cholerae transmission increased substantially across all HDI country groups—although, with 98% of their coastline suitable to the transmission of V cholerae in 2020, it is people in the low HDI country group that have the highest environmental suitability for this disease (indicator 1.3.1). The concurrent and interconnecting risks posed by extreme weather events, infectious disease transmission, and food, water, and financial insecurity are over-burdening the most vulnerable populations. Through multiple simultaneous and interacting health risks, climate change is threatening to reverse years of progress in public health and sustainable development. Even with overwhelming evidence on the health impacts of climate change, countries are not delivering an adaptation response proportionate to the rising risks their populations face. In 2020, 104 (63%) of 166 countries did not have a high level of implementation of national health emergency frameworks, leaving them unprepared to respond to pandemics and climate-related health emergencies (indicator 2.3.1). Importantly, only 18 (55%) of 33 countries with a low HDI had reported at least a medium level of implementation of national health emergency frameworks, compared with 47 (89%) of 53 countries with a very high HDI. In addition, only 47 (52%) of 91 countries reported having a national adaptation plan for health, with insufficient human and financial resources identified as the main barrier for their implementation (indicator 2.1.1). With a world facing an unavoidable temperature rise, even with the most ambitious climate change mitigation, accelerated adaptation is essential to reduce the vulnerabilities of populations to climate change and protect the health of people around the world. AN INEQUITABLE RESPONSE FAILS EVERYONE: 10 months into 2021, global and equitable access to the COVID-19 vaccine had not been delivered—more than 60% of people in high-income countries have received at least one dose of a COVID-19 vaccine compared with just 3·5% of people in low-income countries. Data in this report exposes similar inequities in the global climate change mitigation response. To meet the Paris Agreement goals and prevent catastrophic levels of global warming, global greenhouse gas emissions must reduce by half within a decade. However, at the current pace of reduction, it would take more than 150 years for the energy system to fully decarbonise (indicator 3.1), and the unequal response between countries is resulting in an uneven realisation of the health benefits of a low-carbon transition. The use of public funds to subsidise fossil fuels is partly responsible for the slow decarbonisation rate. Of the 84 countries reviewed, 65 were still providing an overall subsidy to fossil fuels in 2018 and, in many cases, subsidies were equivalent to substantial proportions of the national health budget and could have been redirected to deliver net benefits to health and wellbeing. Furthermore, all the 19 countries whose carbon pricing policies outweighed the effect of any fossil fuels subsidies came from the very high HDI group (indicator 4.2.4). Although countries in the very high HDI group have collectively made the most progress in the decarbonisation of the energy system, they are still the main contributors to CO(2) emissions through the local production of goods and services, accounting for 45% of the global total (indicator 4.2.5). With a slower pace of decarbonisation and poorer air quality regulations than countries in the very high HDI group, the medium and high HDI country groups produce the most fine particle matter (PM(2·5)) emissions and have the highest rates of air pollution-related deaths, which are about 50% higher than the total deaths in the very high HDI group (indicator 3.3). The low HDI group, with comparatively lower amounts of industrial activity than in the other groups, has a local production that contributes to only 0·7% of global CO(2) emissions, and has the lowest mortality rate from ambient air pollution. However, with only 12% of its inhabitants relying on clean fuels and technologies for cooking, the health of these populations is still at risk from dangerously high concentrations of household air pollution (indicator 3.2). Even in the most affluent countries, people in the most deprived areas over-whelmingly bear the burden of health effects from exposure to air pollution. These findings expose the health costs of the delayed and unequal mitigation response and underscore the millions of deaths to be prevented annually through a low-carbon transition that prioritises the health of all populations. However, the world is not on track to realising the health gains of the transition to a low-carbon economy. Current global decarbonisation commitments are insufficient to meet Paris Agreement ambitions and would lead to a roughly 2·4°C average global temperature increase by the end of the century. The current direction of post-COVID-19 spending is threatening to make this situation worse, with just 18% of all the funds committed for economic recovery from the COVID-19 pandemic by the end of 2020 expected to lead to a reduction of greenhouse gas emissions. Indeed, the economic recovery from the pandemic is already predicted to lead to an unprecedented 5% increase in greenhouse gas emissions in 2021, which will bring global anthropogenic emissions back to their peak amounts. In addition, the current economic recession is threatening to undermine the target of mobilising US$100 billion per year from 2020 onwards to promote low-carbon shifts and adaptation responses in the most underserved countries, even though this quantity is minute compared with the trillions allocated to COVID-19 recovery. The high amounts of borrowing that countries have had to resort to during the pandemic could erase their ability to deliver a green recovery and maximise the health gains to their population of a low-carbon transition. AN UNPRECEDENTED OPPORTUNITY TO ENSURE A HEALTHY FUTURE FOR ALL: The overshoot in emissions resulting from a carbon-intensive COVID-19 recovery would irreversibly prevent the world from meeting climate commitments and the Sustainable Development Goals and lock humanity into an increasingly extreme and unpredictable environment. Data in this report expose the health impacts and health inequities of the current world at 1·2°C of warming above pre-industrial levels and supports that, on the current trajectory, climate change will become the defining narrative of human health. However, by directing the trillions of dollars that will be committed to COVID-19 recovery towards the WHO’s prescriptions for a healthy, green recovery, the world could meet the Paris Agreement goals, protect the natural systems that support wellbeing, and minimise inequities through reduced health effects and maximised co-benefits of a universal low-carbon transition. Promoting equitable climate change mitigation and universal access to clean energies could prevent millions of deaths annually from reduced exposure to air pollution, healthier diets, and more active lifestyles, and contribute to reducing health inequities globally. This pivotal moment of economic stimulus represents a historical opportunity to secure the health of present and future generations. There is a glimpse of positive change through several promising trends in this year’s data: electricity generation from renewable wind and solar energy increased by an annual average of 17% between 2013 and 2018 (indicator 3.1); investment in new coal capacity decreased by 10% in 2020 (indicator 4.2.1); and the global number of electric vehicles reached 7·2 million in 2019 (indicator 3.4). Additionally, the global pandemic has driven increased engagement in health and climate change across multiple domains in society, with 91 heads of state making the connection in the 2020 UN General Debate and newly widespread engagement among countries in the very high HDI group (indicator 5.4). Whether COVID-19 recovery supports, or reverses these trends, is yet to be seen. Neither COVID-19 nor climate change respect national borders. Without widespread, accessible vaccination across all countries and societies, SARS-CoV-2 and its new variants will continue to put the health of everybody at risk. Likewise, tackling climate change requires all countries to deliver an urgent and coordinated response, with COVID-19 recovery funds allocated to support and ensure a just transition to a low-carbon future and climate change adaptation across the globe. Leaders of the world have an unprecedented opportunity to deliver a future of improved health, reduced inequity, and economic and environmental sustainability. However, this will only be possible if the world acts together to ensure that no person is left behind.

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    The Lancet
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    UCL Discovery
    Article . 2021
    Data sources: UCL Discovery
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    The Lancet
    Article . 2021 . Peer-reviewed
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    The Lancet
    Article . 2022
    MPG.PuRe
    Article . 2021
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    Authors: Hugh Montgomery; Paul Ekins; Anthony Costello; Mark A. Maslin; +1 Authors

    The health effects of climate change have had relatively little attention from climate scientists and governments. Climate change will be a major threat to population health in the current century through its potential effects on communicable disease, heat stress, food and water security, extreme weather events, vulnerable shelter and population migration. This paper addresses three health-sector strategies to manage the health effects of climate change—promotion of mitigation, tackling the pathways that lead to ill-health and strengthening health systems. Mitigation of greenhouse gas (GHG) emissions is affordable, and low-carbon technologies are available now or will be in the near future. Pathways to ill-health can be managed through better information, poverty reduction, technological innovation, social and cultural change and greater coordination of national and international institutions. Strengthening health systems requires increased investment in order to provide effective public health responses to climate-induced threats to health, equitable treatment of illness, promotion of low-carbon lifestyles and renewable energy solutions within health facilities. Mitigation and adaptation strategies will produce substantial benefits for health, such as reductions in obesity and heart disease, diabetes, stress and depression, pneumonia and asthma, as well as potential cost savings within the health sector. The case for mitigating climate change by reducing GHGs is overwhelming. The need to build population resilience to the global health threat from already unavoidable climate change is real and urgent. Action must not be delayed by contrarians, nor by catastrophic fatalists who say it is all too late.

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    Philosophical Transactions of the Royal Society A Mathematical Physical and Engineering Sciences
    Article . 2011 . Peer-reviewed
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    Authors: Hugh Montgomery; D. Pencheon; J. R. Sneyd;
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    Anaesthesia
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    Anaesthesia
    Article . 2010 . Peer-reviewed
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    Other literature type . 2010
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      Anaesthesia
      Article . 2010 . Peer-reviewed
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    Authors: Hugh Montgomery; Sabaratnam Arulkumaran; David McCoy; Fiona Godlee;

    The IPCC report shows the need for “radical and transformative change” Next week the Intergovernmental Panel on Climate Change (IPCC) will publish its report on the impacts of global warming. Building on its recent update of the physical science of global warming,1 the IPCC’s new report should leave the world in no doubt about the scale and immediacy of the threat to human survival, health, and wellbeing. The IPCC has already concluded that it is “virtually certain that human influence has warmed the global climate system” and that it is “extremely likely that more than half of the observed increase in global average surface temperature from 1951 to 2010” is anthropogenic.1 Its new report outlines the future threats of further global warming: increased scarcity of food and fresh water; extreme weather events; rise in sea level; loss of biodiversity; areas becoming uninhabitable; and mass human migration, conflict and violence. Leaked drafts talk of hundreds of millions displaced in a little over 80 years. This month, the American Association for the Advancement of Science (AAAS) added its voice: “the well being of people of all nations [is] at risk.”2 Such comments reaffirm the conclusions of …

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    Article . 2014 . Peer-reviewed
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    Other literature type . 2014
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      BMJ
      Article . 2014 . Peer-reviewed
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    Authors: Nick Watts; W. Neil Adger; Sonja Ayeb‐Karlsson; Yuqi Bai; +44 Authors

    The Lancet Countdown : le suivi des progrès en matière de santé et de changement climatique est une collaboration de recherche internationale et multidisciplinaire entre des établissements universitaires et des praticiens du monde entier. Il fait suite aux travaux de la Commission Lancet de 2015, qui a conclu que la réponse au changement climatique pourrait être « la plus grande opportunité de santé mondiale du XXIe siècle ». Le compte à rebours du Lancet vise à suivre les impacts sur la santé des risques climatiques ; la résilience et l'adaptation en matière de santé ; les co-bénéfices pour la santé de l'atténuation du changement climatique ; l'économie et la finance ; et l'engagement politique et plus large. Ces domaines d'intervention forment les cinq groupes de travail thématiques du Lancet Countdown et représentent différents aspects de l'association complexe entre la santé et le changement climatique. Ces groupes thématiques fourniront des indicateurs pour une vue d'ensemble mondiale de la santé et du changement climatique ; des études de cas nationales mettant en évidence les pays qui ouvrent la voie ou vont à l'encontre de la tendance ; et un engagement avec un éventail de parties prenantes. Le compte à rebours du Lancet vise finalement à rendre compte chaque année d'une série d'indicateurs dans ces cinq groupes de travail. Ce document décrit les indicateurs potentiels et les domaines d'indicateurs à suivre par la collaboration, avec des suggestions sur les méthodologies et les ensembles de données disponibles pour atteindre cet objectif. Les domaines d'indicateurs proposés doivent être affinés et marquent le début d'un processus de consultation en cours - de novembre 2016 au début de 2017 - pour développer ces domaines, identifier les domaines clés non couverts actuellement et modifier les indicateurs si nécessaire. Cette collaboration cherchera activement à s'engager dans les processus de suivi existants, tels que les objectifs de développement durable des Nations Unies et les profils de pays de l'OMS en matière de climat et de santé. Les indicateurs évolueront également au fil du temps grâce à une collaboration continue avec des experts et un éventail de parties prenantes, et dépendront de l'émergence de nouvelles preuves et connaissances. Au cours de ses travaux, le Lancet Countdown adoptera un processus collaboratif et itératif, qui vise à compléter les initiatives existantes, à accueillir l'engagement avec de nouveaux partenaires et à être ouvert au développement de nouveaux projets de recherche sur la santé et le changement climatique. The Lancet Countdown: tracking progress on health and climate change es una colaboración de investigación internacional y multidisciplinaria entre instituciones académicas y profesionales de todo el mundo. Sigue el trabajo de la Comisión Lancet de 2015, que concluyó que la respuesta al cambio climático podría ser "la mayor oportunidad de salud global del siglo XXI". The Lancet Countdown tiene como objetivo realizar un seguimiento de los impactos en la salud de los peligros climáticos; la resiliencia y la adaptación a la salud; los beneficios colaterales para la salud de la mitigación del cambio climático; la economía y las finanzas; y el compromiso político y más amplio. Estas áreas de enfoque forman los cinco grupos de trabajo temáticos de The Lancet Countdown y representan diferentes aspectos de la compleja asociación entre la salud y el cambio climático. Estos grupos temáticos proporcionarán indicadores para una visión global de la salud y el cambio climático; estudios de casos nacionales que destacan a los países que lideran el camino o van en contra de la tendencia; y el compromiso con una variedad de partes interesadas. En última instancia, The Lancet Countdown tiene como objetivo informar anualmente sobre una serie de indicadores en estos cinco grupos de trabajo. Este documento describe los posibles indicadores y dominios de indicadores a ser rastreados por la colaboración, con sugerencias sobre las metodologías y conjuntos de datos disponibles para lograr este fin. Los dominios de indicadores propuestos requieren un mayor refinamiento y marcan el comienzo de un proceso de consulta continuo, desde noviembre de 2016 hasta principios de 2017, para desarrollar estos dominios, identificar áreas clave que actualmente no están cubiertas y cambiar los indicadores cuando sea necesario. Esta colaboración buscará activamente involucrarse con los procesos de monitoreo existentes, como los Objetivos de Desarrollo Sostenible de la ONU y LOS perfiles climáticos y de salud de los países de la OMS. Los indicadores también evolucionarán con el tiempo a través de la colaboración continua con expertos y una variedad de partes interesadas, y dependerán de la aparición de nuevas pruebas y conocimientos. Durante el transcurso de su trabajo, The Lancet Countdown adoptará un proceso colaborativo e iterativo, que tiene como objetivo complementar las iniciativas existentes, dar la bienvenida al compromiso con nuevos socios y estar abierto al desarrollo de nuevos proyectos de investigación sobre salud y cambio climático. The Lancet Countdown: tracking progress on health and climate change is an international, multidisciplinary research collaboration between academic institutions and practitioners across the world. It follows on from the work of the 2015 Lancet Commission, which concluded that the response to climate change could be "the greatest global health opportunity of the 21st century". The Lancet Countdown aims to track the health impacts of climate hazards; health resilience and adaptation; health co-benefits of climate change mitigation; economics and finance; and political and broader engagement. These focus areas form the five thematic working groups of the Lancet Countdown and represent different aspects of the complex association between health and climate change. These thematic groups will provide indicators for a global overview of health and climate change; national case studies highlighting countries leading the way or going against the trend; and engagement with a range of stakeholders. The Lancet Countdown ultimately aims to report annually on a series of indicators across these five working groups. This paper outlines the potential indicators and indicator domains to be tracked by the collaboration, with suggestions on the methodologies and datasets available to achieve this end. The proposed indicator domains require further refinement, and mark the beginning of an ongoing consultation process-from November, 2016 to early 2017-to develop these domains, identify key areas not currently covered, and change indicators where necessary. This collaboration will actively seek to engage with existing monitoring processes, such as the UN Sustainable Development Goals and WHO's climate and health country profiles. The indicators will also evolve over time through ongoing collaboration with experts and a range of stakeholders, and be dependent on the emergence of new evidence and knowledge. During the course of its work, the Lancet Countdown will adopt a collaborative and iterative process, which aims to complement existing initiatives, welcome engagement with new partners, and be open to developing new research projects on health and climate change. العد التنازلي لمجلة لانسيت: تتبع التقدم المحرز في مجال الصحة وتغير المناخ هو تعاون بحثي دولي متعدد التخصصات بين المؤسسات الأكاديمية والممارسين في جميع أنحاء العالم. ويتبع ذلك عمل لجنة لانسيت لعام 2015، التي خلصت إلى أن الاستجابة لتغير المناخ يمكن أن تكون "أعظم فرصة صحية عالمية في القرن الحادي والعشرين". يهدف العد التنازلي لمجلة لانسيت إلى تتبع الآثار الصحية للمخاطر المناخية ؛ والمرونة الصحية والتكيف ؛ والفوائد الصحية المشتركة للتخفيف من آثار تغير المناخ ؛ والاقتصاد والتمويل ؛ والمشاركة السياسية والأوسع نطاقًا. تشكل مجالات التركيز هذه مجموعات العمل المواضيعية الخمسة للعد التنازلي لمجلة لانسيت وتمثل جوانب مختلفة من الارتباط المعقد بين الصحة وتغير المناخ. وستوفر هذه المجموعات المواضيعية مؤشرات لإلقاء نظرة عامة عالمية على الصحة وتغير المناخ ؛ ودراسات حالة وطنية تسلط الضوء على البلدان التي تقود الطريق أو تسير عكس الاتجاه ؛ والمشاركة مع مجموعة من أصحاب المصلحة. يهدف العد التنازلي لمجلة لانسيت في نهاية المطاف إلى تقديم تقرير سنوي عن سلسلة من المؤشرات عبر مجموعات العمل الخمس هذه. تحدد هذه الورقة المؤشرات المحتملة ومجالات المؤشرات التي سيتم تتبعها من خلال التعاون، مع اقتراحات حول المنهجيات ومجموعات البيانات المتاحة لتحقيق هذه الغاية. تتطلب مجالات المؤشرات المقترحة مزيدًا من التنقيح، وتمثل بداية عملية تشاور مستمرة - من نوفمبر 2016 إلى أوائل 2017 - لتطوير هذه المجالات، وتحديد المجالات الرئيسية غير المشمولة حاليًا، وتغيير المؤشرات عند الضرورة. سيسعى هذا التعاون بنشاط إلى المشاركة في عمليات الرصد القائمة، مثل أهداف الأمم المتحدة للتنمية المستدامة والملامح القطرية للمناخ والصحة لمنظمة الصحة العالمية. ستتطور المؤشرات أيضًا بمرور الوقت من خلال التعاون المستمر مع الخبراء ومجموعة من أصحاب المصلحة، وستعتمد على ظهور أدلة ومعارف جديدة. خلال عملها، سيعتمد العد التنازلي لمجلة لانسيت عملية تعاونية وتكرارية، تهدف إلى استكمال المبادرات الحالية، والترحيب بالمشاركة مع شركاء جدد، والانفتاح على تطوير مشاريع بحثية جديدة حول الصحة وتغير المناخ.

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    The Lancet
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    UCL Discovery
    Article . 2016
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    The Lancet
    Article . 2017 . Peer-reviewed
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    Other literature type . 2017
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    Other literature type . 2017
    Data sources: Datacite
    The Lancet
    Article . 2018
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    Authors: Azhar Tarbhai; Angela S. McNelly; Angela S. McNelly; Angela S. McNelly; +17 Authors

    Acute skeletal muscle wasting in critical illness is associated with excess morbidity and mortality. Continuous feeding may suppress muscle protein synthesis as a result of the muscle-full effect, unlike intermittent feeding, which may ameliorate it.Does intermittent enteral feed decrease muscle wasting compared with continuous feed in critically ill patients?In a phase 2 interventional single-blinded randomized controlled trial, 121 mechanically ventilated adult patients with multiorgan failure were recruited following prospective informed consultee assent. They were randomized to the intervention group (intermittent enteral feeding from six 4-hourly feeds per 24 h, n = 62) or control group (standard continuous enteral feeding, n = 59). The primary outcome was 10-day loss of rectus femoris muscle cross-sectional area determined by ultrasound. Secondary outcomes included nutritional target achievements, plasma amino acid concentrations, glycemic control, and physical function milestones.Muscle loss was similar between arms (-1.1% [95% CI, -6.1% to -4.0%]; P = .676). More intermittently fed patients received 80% or more of target protein (OR, 1.52 [1.16-1.99]; P < .001) and energy (OR, 1.59 [1.21-2.08]; P = .001). Plasma branched-chain amino acid concentrations before and after feeds were similar between arms on trial day 1 (71 μM [44-98 μM]; P = .547) and trial day 10 (239 μM [33-444 μM]; P = .178). During the 10-day intervention period the coefficient of variation for glucose concentrations was higher with intermittent feed (17.84 [18.6-20.4]) vs continuous feed (12.98 [14.0-15.7]; P < .001). However, days with reported hypoglycemia and insulin usage were similar in both groups. Safety profiles, gastric intolerance, physical function milestones, and discharge destinations did not differ between groups.Intermittent feeding in early critical illness is not shown to preserve muscle mass in this trial despite resulting in a greater achievement of nutritional targets than continuous feeding. However, it is feasible and safe.ClinicalTrials.gov; No.: NCT02358512; URL: www.clinicaltrials.gov.

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    CHEST Journal
    Article . 2021
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      CHEST Journal
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    Authors: Hugh Montgomery;
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    Biofuel Research Journal
    Article . 2017 . Peer-reviewed
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    Biofuel Research Journal
    Article . 2017
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  • Authors: Hugh Montgomery; Nick Watts; Anthony Costello;

    They need to use their ability to communicate bad news in a way that stimulates a positive response

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    Authors: Watts, N.; Adger, W.N.; Agnolucci, P.; Blackstock, J.; +41 Authors

    The 2015 Lancet Commission on Health and Climate Change has been formed to map out the impacts of climate change, and the necessary policy responses, in order to ensure the highest attainable stand ...

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    Authors: White S. M.; Shelton C. L.; Gelb A. W.; Lawson C.; +48 Authors

    SummaryThe Earth’s mean surface temperature is already approximately 1.1°C higher than pre‐industrial levels. Exceeding a mean 1.5°C rise by 2050 will make global adaptation to the consequences of climate change less possible. To protect public health, anaesthesia providers need to reduce the contribution their practice makes to global warming. We convened a Working Group of 45 anaesthesia providers with a recognised interest in sustainability, and used a three‐stage modified Delphi consensus process to agree on principles of environmentally sustainable anaesthesia that are achievable worldwide. The Working Group agreed on the following three important underlying statements: patient safety should not be compromised by sustainable anaesthetic practices; high‐, middle‐ and low‐income countries should support each other appropriately in delivering sustainable healthcare (including anaesthesia); and healthcare systems should be mandated to reduce their contribution to global warming. We set out seven fundamental principles to guide anaesthesia providers in the move to environmentally sustainable practice, including: choice of medications and equipment; minimising waste and overuse of resources; and addressing environmental sustainability in anaesthetists’ education, research, quality improvement and local healthcare leadership activities. These changes are achievable with minimal material resource and financial investment, and should undergo re‐evaluation and updates as better evidence is published. This paper discusses each principle individually, and directs readers towards further important references.

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    Anaesthesia
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    Authors: Romanello, Marina; McGushin, Alice; Di Napoli, Claudia; Drummond, Paul; +89 Authors

    The Lancet Countdown is an international collaboration that independently monitors the health consequences of a changing climate. Publishing updated, new, and improved indicators each year, the Lancet Countdown represents the consensus of leading researchers from 43 academic institutions and UN agencies. The 44 indicators of this report expose an unabated rise in the health impacts of climate change and the current health consequences of the delayed and inconsistent response of countries around the globe—providing a clear imperative for accelerated action that puts the health of people and planet above all else. The 2021 report coincides with the UN Framework Convention on Climate Change 26th Conference of the Parties (COP26), at which countries are facing pressure to realise the ambition of the Paris Agreement to keep the global average temperature rise to 1·5°C and to mobilise the financial resources required for all countries to have an effective climate response. These negotiations unfold in the context of the COVID-19 pandemic—a global health crisis that has claimed millions of lives, affected livelihoods and communities around the globe, and exposed deep fissures and inequities in the world’s capacity to cope with, and respond to, health emergencies. Yet, in its response to both crises, the world is faced with an unprecedented opportunity to ensure a healthy future for all. DEEPENING INEQUITIES IN A WARMING WORLD: Record temperatures in 2020 resulted in a new high of 3·1 billion more person-days of heatwave exposure among people older than 65 years and 626 million more person-days affecting children younger than 1 year, compared with the annual average for the 1986–2005 baseline (indicator 1.1.2). Looking to 2021, people older than 65 years or younger than 1 year, along with people facing social disadvantages, were the most affected by the record-breaking temperatures of over 40°C in the Pacific Northwest areas of the USA and Canada in June, 2021—an event that would have been almost impossible without human-caused climate change. Although the exact number will not be known for several months, hundreds of people have died prematurely from the heat. Furthermore, populations in countries with low and medium levels of UN-defined human development index (HDI) have had the biggest increase in heat vulnerability during the past 30 years, with risks to their health further exacerbated by the low availability of cooling mechanisms and urban green space (indicators 1.1.1, 2.3.2, and 2.3.3). Agricultural workers in countries with low and medium HDI were among the worst affected by exposure to extreme temperatures, bearing almost half of the 295 billion potential work hours lost due to heat in 2020 (indicator 1.1.4). These lost work hours could have devastating economic consequences to these already vulnerable workers—data in this year’s report shows that the average potential earnings lost in countries in the low HDI group were equivalent to 4–8% of the national gross domestic product (indicator 4.1.3). Through these effects, rising average temperatures, and altered rainfall patterns, climate change is beginning to reverse years of progress in tackling the food and water insecurity that still affects the most underserved populations around the world, denying them an essential aspect of good health. During any given month in 2020, up to 19% of the global land surface was affected by extreme drought; a value that had not exceeded 13% between 1950 and 1999 (indicator 1.2.2). In parallel with drought, warm temperatures are affecting the yield potential of the world’s major staple crops—a 6·0% reduction for maize; 3·0% for winter wheat; 5·4% for soybean; and 1·8% for rice in 2020, relative to 1981–2010 (indicator 1.4.1)—exposing the rising risk of food insecurity. Adding to these health hazards, the changing environmental conditions are also increasing the suitability for the transmission of many water-borne, air-borne, food-borne, and vector-borne pathogens. Although socioeconomic development, public health interventions, and advances in medicine have reduced the global burden of infectious disease transmission, climate change could undermine eradication efforts. The number of months with environmentally suitable conditions for the transmission of malaria (Plasmodium falciparum) rose by 39% from 1950–59 to 2010–19 in densely populated highland areas in the low HDI group, threatening highly disadvantaged populations who were comparatively safer from this disease than those in the lowland areas (indicator 1.3.1). The epidemic potential for dengue virus, Zika virus, and chikungunya virus, which currently primarily affect populations in central America, South America, the Caribbean, Africa, and south Asia, increased globally, with a basic reproductive rate increase of 13% for transmission by Aedes aegypti and 7% for transmission by Aedes albopictus compared with the 1950s. The biggest relative increase in basic reproductive rate of these arboviruses was seen in countries in the very high HDI group (indicator 1.3.1); however, people in the low HDI group are confronted with the highest vulnerability to these arboviruses (indicator 1.3.2). Similar findings are observed in the environmental suitability for Vibrio cholerae, a pathogen estimated to cause almost 100 000 deaths annually, particularly among populations with poor access to safe water and sanitation. Between 2003 and 2019, the coastal areas suitable for V cholerae transmission increased substantially across all HDI country groups—although, with 98% of their coastline suitable to the transmission of V cholerae in 2020, it is people in the low HDI country group that have the highest environmental suitability for this disease (indicator 1.3.1). The concurrent and interconnecting risks posed by extreme weather events, infectious disease transmission, and food, water, and financial insecurity are over-burdening the most vulnerable populations. Through multiple simultaneous and interacting health risks, climate change is threatening to reverse years of progress in public health and sustainable development. Even with overwhelming evidence on the health impacts of climate change, countries are not delivering an adaptation response proportionate to the rising risks their populations face. In 2020, 104 (63%) of 166 countries did not have a high level of implementation of national health emergency frameworks, leaving them unprepared to respond to pandemics and climate-related health emergencies (indicator 2.3.1). Importantly, only 18 (55%) of 33 countries with a low HDI had reported at least a medium level of implementation of national health emergency frameworks, compared with 47 (89%) of 53 countries with a very high HDI. In addition, only 47 (52%) of 91 countries reported having a national adaptation plan for health, with insufficient human and financial resources identified as the main barrier for their implementation (indicator 2.1.1). With a world facing an unavoidable temperature rise, even with the most ambitious climate change mitigation, accelerated adaptation is essential to reduce the vulnerabilities of populations to climate change and protect the health of people around the world. AN INEQUITABLE RESPONSE FAILS EVERYONE: 10 months into 2021, global and equitable access to the COVID-19 vaccine had not been delivered—more than 60% of people in high-income countries have received at least one dose of a COVID-19 vaccine compared with just 3·5% of people in low-income countries. Data in this report exposes similar inequities in the global climate change mitigation response. To meet the Paris Agreement goals and prevent catastrophic levels of global warming, global greenhouse gas emissions must reduce by half within a decade. However, at the current pace of reduction, it would take more than 150 years for the energy system to fully decarbonise (indicator 3.1), and the unequal response between countries is resulting in an uneven realisation of the health benefits of a low-carbon transition. The use of public funds to subsidise fossil fuels is partly responsible for the slow decarbonisation rate. Of the 84 countries reviewed, 65 were still providing an overall subsidy to fossil fuels in 2018 and, in many cases, subsidies were equivalent to substantial proportions of the national health budget and could have been redirected to deliver net benefits to health and wellbeing. Furthermore, all the 19 countries whose carbon pricing policies outweighed the effect of any fossil fuels subsidies came from the very high HDI group (indicator 4.2.4). Although countries in the very high HDI group have collectively made the most progress in the decarbonisation of the energy system, they are still the main contributors to CO(2) emissions through the local production of goods and services, accounting for 45% of the global total (indicator 4.2.5). With a slower pace of decarbonisation and poorer air quality regulations than countries in the very high HDI group, the medium and high HDI country groups produce the most fine particle matter (PM(2·5)) emissions and have the highest rates of air pollution-related deaths, which are about 50% higher than the total deaths in the very high HDI group (indicator 3.3). The low HDI group, with comparatively lower amounts of industrial activity than in the other groups, has a local production that contributes to only 0·7% of global CO(2) emissions, and has the lowest mortality rate from ambient air pollution. However, with only 12% of its inhabitants relying on clean fuels and technologies for cooking, the health of these populations is still at risk from dangerously high concentrations of household air pollution (indicator 3.2). Even in the most affluent countries, people in the most deprived areas over-whelmingly bear the burden of health effects from exposure to air pollution. These findings expose the health costs of the delayed and unequal mitigation response and underscore the millions of deaths to be prevented annually through a low-carbon transition that prioritises the health of all populations. However, the world is not on track to realising the health gains of the transition to a low-carbon economy. Current global decarbonisation commitments are insufficient to meet Paris Agreement ambitions and would lead to a roughly 2·4°C average global temperature increase by the end of the century. The current direction of post-COVID-19 spending is threatening to make this situation worse, with just 18% of all the funds committed for economic recovery from the COVID-19 pandemic by the end of 2020 expected to lead to a reduction of greenhouse gas emissions. Indeed, the economic recovery from the pandemic is already predicted to lead to an unprecedented 5% increase in greenhouse gas emissions in 2021, which will bring global anthropogenic emissions back to their peak amounts. In addition, the current economic recession is threatening to undermine the target of mobilising US$100 billion per year from 2020 onwards to promote low-carbon shifts and adaptation responses in the most underserved countries, even though this quantity is minute compared with the trillions allocated to COVID-19 recovery. The high amounts of borrowing that countries have had to resort to during the pandemic could erase their ability to deliver a green recovery and maximise the health gains to their population of a low-carbon transition. AN UNPRECEDENTED OPPORTUNITY TO ENSURE A HEALTHY FUTURE FOR ALL: The overshoot in emissions resulting from a carbon-intensive COVID-19 recovery would irreversibly prevent the world from meeting climate commitments and the Sustainable Development Goals and lock humanity into an increasingly extreme and unpredictable environment. Data in this report expose the health impacts and health inequities of the current world at 1·2°C of warming above pre-industrial levels and supports that, on the current trajectory, climate change will become the defining narrative of human health. However, by directing the trillions of dollars that will be committed to COVID-19 recovery towards the WHO’s prescriptions for a healthy, green recovery, the world could meet the Paris Agreement goals, protect the natural systems that support wellbeing, and minimise inequities through reduced health effects and maximised co-benefits of a universal low-carbon transition. Promoting equitable climate change mitigation and universal access to clean energies could prevent millions of deaths annually from reduced exposure to air pollution, healthier diets, and more active lifestyles, and contribute to reducing health inequities globally. This pivotal moment of economic stimulus represents a historical opportunity to secure the health of present and future generations. There is a glimpse of positive change through several promising trends in this year’s data: electricity generation from renewable wind and solar energy increased by an annual average of 17% between 2013 and 2018 (indicator 3.1); investment in new coal capacity decreased by 10% in 2020 (indicator 4.2.1); and the global number of electric vehicles reached 7·2 million in 2019 (indicator 3.4). Additionally, the global pandemic has driven increased engagement in health and climate change across multiple domains in society, with 91 heads of state making the connection in the 2020 UN General Debate and newly widespread engagement among countries in the very high HDI group (indicator 5.4). Whether COVID-19 recovery supports, or reverses these trends, is yet to be seen. Neither COVID-19 nor climate change respect national borders. Without widespread, accessible vaccination across all countries and societies, SARS-CoV-2 and its new variants will continue to put the health of everybody at risk. Likewise, tackling climate change requires all countries to deliver an urgent and coordinated response, with COVID-19 recovery funds allocated to support and ensure a just transition to a low-carbon future and climate change adaptation across the globe. Leaders of the world have an unprecedented opportunity to deliver a future of improved health, reduced inequity, and economic and environmental sustainability. However, this will only be possible if the world acts together to ensure that no person is left behind.

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    The Lancet
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    UCL Discovery
    Article . 2021
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    The Lancet
    Article . 2021 . Peer-reviewed
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    The Lancet
    Article . 2022
    MPG.PuRe
    Article . 2021
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  • image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
    Authors: Hugh Montgomery; Paul Ekins; Anthony Costello; Mark A. Maslin; +1 Authors

    The health effects of climate change have had relatively little attention from climate scientists and governments. Climate change will be a major threat to population health in the current century through its potential effects on communicable disease, heat stress, food and water security, extreme weather events, vulnerable shelter and population migration. This paper addresses three health-sector strategies to manage the health effects of climate change—promotion of mitigation, tackling the pathways that lead to ill-health and strengthening health systems. Mitigation of greenhouse gas (GHG) emissions is affordable, and low-carbon technologies are available now or will be in the near future. Pathways to ill-health can be managed through better information, poverty reduction, technological innovation, social and cultural change and greater coordination of national and international institutions. Strengthening health systems requires increased investment in order to provide effective public health responses to climate-induced threats to health, equitable treatment of illness, promotion of low-carbon lifestyles and renewable energy solutions within health facilities. Mitigation and adaptation strategies will produce substantial benefits for health, such as reductions in obesity and heart disease, diabetes, stress and depression, pneumonia and asthma, as well as potential cost savings within the health sector. The case for mitigating climate change by reducing GHGs is overwhelming. The need to build population resilience to the global health threat from already unavoidable climate change is real and urgent. Action must not be delayed by contrarians, nor by catastrophic fatalists who say it is all too late.

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    Philosophical Transactions of the Royal Society A Mathematical Physical and Engineering Sciences
    Article . 2011 . Peer-reviewed
    License: Royal Society Data Sharing and Accessibility
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