• Energy Research
• Metis Radboud University close

Data from the Netherlands Cohort Study on Diet and Cancer were used to investigate the association between anthropometry, energy intake, and physical activity and risk of renal cell carcinoma (RCC). The Netherlands Cohort Study on Diet and Cancer consists of 120,852 men and women aged 55-69 years who completed a self-administered questionnaire at baseline (1986). A case-cohort approach was used. After 9.3 years of follow-up, 275 microscopically confirmed incident cases were available for analysis. Incidence rate ratios for RCC were estimated using Cox proportional hazards models. Height was associated with RCC risk only in women (per 5-cm increment, rate ratio (RR) = 1.23, 95% confidence interval (CI): 1.03, 1.46). Body mass index (weight (kg)/height (m)(2)) was associated with increased risk of RCC (per 1-kg/m(2 )increment, RR = 1.07, 95% CI: 1.02, 1.12) for men and women, as was gain in body mass index from age 20 years to baseline (per 1-kg/m(2 )increment, RR = 1.06, 95% CI: 1.01, 1.10). Energy intake was not related to RCC risk, while a possible protective effect was observed for physical activity in men. These results suggest that body mass index and gain in body mass index since age 20 are associated with increased risk of RCC.

Data from the Netherlands Cohort Study on Diet and Cancer were used to investigate the association between anthropometry, energy intake, and physical activity and risk of renal cell carcinoma (RCC). The Netherlands Cohort Study on Diet and Cancer consists of 120,852 men and women aged 55-69 years who completed a self-administered questionnaire at baseline (1986). A case-cohort approach was used. After 9.3 years of follow-up, 275 microscopically confirmed incident cases were available for analysis. Incidence rate ratios for RCC were estimated using Cox proportional hazards models. Height was associated with RCC risk only in women (per 5-cm increment, rate ratio (RR) = 1.23, 95% confidence interval (CI): 1.03, 1.46). Body mass index (weight (kg)/height (m)(2)) was associated with increased risk of RCC (per 1-kg/m(2 )increment, RR = 1.07, 95% CI: 1.02, 1.12) for men and women, as was gain in body mass index from age 20 years to baseline (per 1-kg/m(2 )increment, RR = 1.06, 95% CI: 1.01, 1.10). Energy intake was not related to RCC risk, while a possible protective effect was observed for physical activity in men. These results suggest that body mass index and gain in body mass index since age 20 are associated with increased risk of RCC.

AbstractThe inclusive top quark pair ($$t\bar{t}$$ t t ¯ ) production cross-section $$\sigma _{t\bar{t}}$$ σ t t ¯ has been measured in proton–proton collisions at $$\sqrt{s}=13\,\text {TeV}$$ s = 13 TeV , using 36.1 fb$$^{-1}$$ - 1 of data collected in 2015–2016 by the ATLAS experiment at the LHC. Using events with an opposite-charge $$e\mu $$ e μ pair and b-tagged jets, the cross-section is measured to be: $$\begin{aligned} \sigma _{t\bar{t}} = 826.4 \pm 3.6\,\mathrm {(stat)}\ \pm 11.5\,\mathrm {(syst)}\ \pm 15.7\,\mathrm {(lumi)}\ \pm 1.9\,\mathrm {(beam)}\,\mathrm {pb}, \end{aligned}$$ σ t t ¯ = 826.4 ± 3.6 ( stat ) ± 11.5 ( syst ) ± 15.7 ( lumi ) ± 1.9 ( beam ) pb , where the uncertainties reflect the limited size of the data sample, experimental and theoretical systematic effects, the integrated luminosity, and the LHC beam energy, giving a total uncertainty of 2.4%. The result is consistent with theoretical QCD calculations at next-to-next-to-leading order. It is used to determine the top quark pole mass via the dependence of the predicted cross-section on $$m_t^{\mathrm{pole}}$$ m t pole , giving $$m_t^{\mathrm{pole}}=173.1^{+2.0}_{-2.1}\,\text {GeV}$$ m t pole = 173 . 1 - 2.1 + 2.0 GeV . It is also combined with measurements at $$\sqrt{s}=7\,\text {TeV}$$ s = 7 TeV and $$\sqrt{s}=8\,\text {TeV}$$ s = 8 TeV to derive ratios and double ratios of $$t\bar{t}$$ t t ¯ and Z cross-sections at different energies. The same event sample is used to measure absolute and normalised differential cross-sections as functions of single-lepton and dilepton kinematic variables, and the results are compared with predictions from various Monte Carlo event generators.