• Energy Research
• CH close
• PK close

Background and Aims: This study aims at evaluating the ease of use of the new calorimeter for the measurement of energy expenditure (EE) in intensive care unit (ICU) patients. EE in ICU patients is highly variable depending on the severity of the disease and treatments. Clinicians need to measure EE by indirect calorimetry (IC) to optimize nutritional support for the better clinical outcome. However, indirect calorimeters available on the market have insufficient accuracy for clinical and research use. Difficulties of handling and interpretation of results often limit IC in ICU patients. An accurate, easy-to-use calorimeter has been developed to meet these needs. The Study Device: The new calorimeter (Quark RMR 2.0, COSMED) is capable of IC measurements in mechanically ventilated patients without warm-up and limited calibration. The disposable in-line pneumotach flow meter and direct sampling of respiratory gas from the ventilator circuit enables the accurate measurement of oxygen consumption volume (VO2) and CO2 production volume (VCO2) to derive the energy expenditure. The software interface to manage the device and the collected data provides easy-to-use, user-friendly interface. This calorimeter bears an European Commission (EC) Conformity Mark, and will be used in the way it is intended to be used as described in the instruction manual. Currently used indirect calorimeters at each study center will be used as the comparator. This study will evaluate the ease of use of the new calorimeter (Quark RMR 2.0 (COSMED, Italy)) in intensive care unit (ICU) patients compared to currently used calorimeters (i.e. Quark RMR 1.0(COSMED, Italy) or Deltatrac Metabolic Monitor (Datex, Finland)), as well as the stability and the feasibility of the measurements in various clinically relevant situations. Time needed to prepare and start indirect calorimetry (IC) measurement will be compared as the measure of the ease of use of the calorimeter.

The prevalence of type 1 diabetes has been steadily increasing for about 20 years. Despite therapeutic progress, between 20 and 65% of people with diabetes develop diabetic neuropathy, resulting in increased morbidity and mortality. Diabetic neuropathy is not limited to sensitive pain in the lower limbs. It also affects the fibres of the autonomic nervous system (ANS), which results in systemic complications, often disabling (erectile dysfunction, dysidrosis, gastroparesis, orthostatism, etc.) and a probable alteration in the body's thermogenic capacities, although this possibility has not been studied in humans. In rodents, it is possible to activate induced thermogenesis via central stimulation of the ANS or to inactivate it, which promotes the development of obesity and greater insulin resistance. This knowledge is based on cellular and animal models that have identified the bio-molecular mechanisms that give brown adipose tissue (BAT) the ability to dissipate energy in the form of heat. Induced thermogenesis is mediated by decoupling proteins 1 (DCS-1) located on the mitochondrial inner membrane of the TAB. DCS-1 decouple oxidative phosphorylation from ATP production, dissipating the proton gradient. The activation of UCP1 is particularly influenced by the sympathetic system and more particularly by catecholamines which will bind to ß3 adrenergic receptors (Rß3). In humans, the persistence of active areas of TAB has recently been demonstrated by positron emission tomography (PET) imaging using a glucose analogue radiotracer, 18F-Fluoro-Deoxy-Glucose (18F-FDG), coupled with the scanner (CT). Recently, it has been shown that the use of 18F-FDG PET coupled with magnetic resonance (MRI) is equally effective in differentiating TAB from white fat tissue with less patient irradiation. The activity of the TAB is estimated using the measurement of SUV (standard uptake value) which represents the total glycolytic activity of the tissue and is also commonly referred to as the total metabolic volume. It has been shown in humans that TAB activity is inversely correlated with body mass index and age and positively correlated with exposure to cold and stress levels[6]. Among diabetics, the data are disparate but the spontaneous prevalence of TAB appears to be reduced compared to the general population (1.1% vs 7.5%). To date, no studies have investigated a possible link between the decrease in TAB activity observed in diabetics and the presence of autonomic neuropathy, which is a common and often under-diagnosed complication of diabetes. The main purpose of this study is to evaluate whether the activity and distribution of TAB in patients with diabetes is influenced by the presence of diabetic neuropathy. On the other hand, if the existence of diabetic neuropathy influences energy expenditure in the event of exposure to cold. Finally, whether any differences in the activity and distribution of TAB could be related to changes in the central nervous system. The investigators plan to include a total of 24 patients with type 1 diabetes and separate them into 2 groups: group A; no neuropathic complications and group B; presence of neuropathy. All patients will be characterized in terms of clinical, metabolic and energy expenditure. The activity of the TAB will be evaluated through the use of 18F-FDG PET/IRM imaging, after a cold stimulation protocol (refrigerated jacket) in order to activate the TAB in a homogeneous manner among the participants. Influence of diabetic neuropathy on cold induced brown adipose tissue in type 1 diabetic patients.

This readme file provides all data and R codes used to perform the analyses presented in Figs. 2-4 of the main text and Supplementary Information Figures S1-S2-S3. FIGURE 2 - Seasonally_dated_GDs.txt: Contains information on the timing (Season) of rockfall (GD) in a given tree (Id) and a given year (yr) over the past 100 years. Inv refers to the operators which analyzed growth disturbances in the tree-ring series. Lat / Long refers to the position of the tree in CH1903/ Swiss Grid projection. Intensity (1-4) refers to (1), intermediate (2) and strong (3) GD. Intensity 4 was attributed to injuries (I). Only the 408 GD rated 3 (strong TRD) and 4 (injuries) were used in Fig. 2. Acronyms used for Response_type read as follows: TRD: Tangential rows of traumatic resin ducts; I: Injuries. Acronyms used for Season refer to Dormancy (1_D), early (2_EE), middle (3_ME) and late (4_LE) earlywood, whereas a GD found in the latewood was attributed to either the early (5_EL) or late (6_LL) latewood. - Trends_in_seasonality_R1.R: The data contained in "Seasonally_dated_GDs" were processed with the R script "Trends_in_Seasonality.R". This seasonal trend analysis code is inspired by work published by Schlögl et al. (2021; https://doi.org/10.1016/j.crm.2021.100294) and Heiser et al. (2022; https://doi.org/10.1029/2011JF002262). FIGURE 3-4-S1 - Tasch_GD.txt: Contains the raw data on rockfall impacts (GD) in a given year (yr) as found in all trees available in that same year (Sample_depth) as well as the cumulated diameter at breast height (cumulated_DBH) of all trees present in that same year. - Rockfall_frequency_climate.R: The data contained in "Tasch_GD.txt" were processed with the R script "Rockfall_frequency_climate.R". - The temperature (Imfeld23_tmp.txt) and precipitation (Imfeld23_prc.txt) data used in Fig. 3 are from the Imfeld et al. 2023 (10.5194/cp-19-703-2023) gridded dataset (1x1 km lat/long) and were extracted at the grid point centered on the Täschgufer site. - The script set with temperature series enables to compute Fig. 4 (l.149:216) and Fig. 3 (l. 216:330); the script set with precipitation series enables to compute Fig. S1 FIGURE S2 - Tasch_GD.txt: Contains the raw data on rockfall impacts (GD) at the Täschgufer site in a given year (yr) as found in all trees available in that same year (Sample_depth) as well as the cumulated diameter at breast height (cumulated_DBH) of all trees present in that same year. - Rockfall_frequency_borehole.R: is adapted from "Rockfall_frequency_climate.R" to work with the borehole dates. - Corvatsch0_6R1: Contains the Corvatsch borehole temperature series (2000-2020, 0.6m depth) (Hoelzle, M. et al. https://doi.org/10.5194/essd-14-1531-2022, 2022). FIGURE S3 - Plattje_GD.txt: Contains the raw data on rockfall impacts (GD) at the Plattje site in a given year (yr) as found all trees available in that same year (Sample_depth) as well as the cumulated diameter at breast height (cumulated_DBH) of all trees present in that same year. - - Rockfall_frequency_climate_Plattje.R: The data contained in "Plattje_GD.txt" were processed with the R script "Rockfall_frequency_climate_Plattje.R". - The temperature (Imfeld23_tmp_Plattje.txt) and precipitation (Imfeld23_prc_Plattje.txt) data used in Fig. 3 are from Imfeld et al. 2023 (10.5194/cp-19-703-2023) gridded dataset (1x1 km lat/long) and were extracted at the grid point centered on the Plattje site.

Dataset of process simulations results of the natural gas sweetening and flue gas treatment (first and second sheet, respectively as indicated by the sheet name in the .xlsx file). The dataset refers to the publication Bayesian Symbolic Learning to Build Analytical Correlations from Rigorous Process Simulations: Application to CO2 Capture Technologies by V. Negri, Vàzquey D., Sales-Pardo, Marta, Guimerà, R. and Guillén-Gosàlbez, G. The training and testing dataset are used to generate the figures in the main manuscript and supplementary information.

Aim: Climate warming and biodiversity loss both alter plant productivity, yet we lack an understanding of how biodiversity regulates the responses of ecosystems to warming. In this study, we examine how plant diversity regulates the responses of grassland productivity to experimental warming using meta-analytic techniques. Location: Global Major taxa studied: Grassland ecosystems Methods: Our meta-analysis is based on warming responses of 40 different plant communities obtained from 20 independent studies on grasslands across five continents. Results: Our results show that plant diversity and its responses to warming were the most important factors regulating the warming effects on plant productivity, among all the factors considered (plant diversity, climate and experimental settings). Specifically, warming increased plant productivity when plant diversity (indicated by effective number of species) in grasslands was lesser than 10, whereas warming decreased plant productivity when plant diversity was greater than 10. Moreover, the structural equation modelling showed that the magnitude of warming enhanced plant productivity by increasing the performance of dominant plant species in grasslands of diversity lesser than 10. The negative effects of warming on productivity in grasslands with plant diversity greater than 10 were partly explained by diversity-induced decline in plant dominance. Main Conclusions: Our findings suggest that the positive or negative effect of warming on grassland productivity depends on how biodiverse a grassland is. This could mainly owe to differences in how warming may affect plant dominance and subsequent shifts in interspecific interactions in grasslands of different plant diversity levels.

This data set contains the essential files used as input for the analysis, intermediate files produced during the analysis, and the key output fields. The code of the analysis is available here: https://github.com/VUB-HYDR/2021_Thiery_etal_Science Input fields: - isimip.zip: Postprocessed ISIMIP2b simulation output. This data set is very similar to the data presented in Lange et al. (2020 Earth's Future) but includes selected additional impact models and scenarios (notably RCP8.5). This data set also includes the gridded population data. - GMT_50pc_manualoutput_4pathways.xlsx: Global mean temperature anomaly trajectories from the IPCC SR15 - wcde_data.xlsx: postprocessed cohort size data originally obtained from the Wittgenstein Centre Human Capital Data Explorer. - WPP2019_MORT_F16_1_LIFE_EXPECTANCY_BY_AGE_BOTH_SEXES.xlsx: Postprocessed life expectancy data originally obtained from the UNited Nations World Population Programme Intermediate files *only use if you're interested in reproducing the results*: - workspaces.zip: Postprocessed ISIMIP2b simulation output. These matlab workspaces contain data on land area annually exposed to extreme events which is stored in a format designed to speed up the analysis. - mw_isimip.mat: ISIMIP2 simulations metadata (e.g. model, gcm and rcp name per simulation) - mw_countries.mat: information on the countries used in the analysis (e.g. border polygon coordinates) - mw_exposure.mat: age-dependent exposure computed from the ISIMIP and population data - mw_exposure_pic.mat: pre-industrial control age-dependent exposure computed from the ISIMIP and population data - mw_exposure_pic_coldwaves.mat: pre-industrial control age-dependent exposure to coldwaves computed from the ISIMIP and population data Output of the analysis: - mw_output.mat: Matlab workspace containing all variables produced during the analysis presented in thepaper. Use this file if you wish to look up certain numbers or want to use the study results for further analysis.

Project: Coupled Model Intercomparison Project Phase 6 (CMIP6) datasets - These data have been generated as part of the internationally-coordinated Coupled Model Intercomparison Project Phase 6 (CMIP6; see also GMD Special Issue: http://www.geosci-model-dev.net/special_issue590.html). The simulation data provides a basis for climate research designed to answer fundamental science questions and serves as resource for authors of the Sixth Assessment Report of the Intergovernmental Panel on Climate Change (IPCC-AR6). CMIP6 is a project coordinated by the Working Group on Coupled Modelling (WGCM) as part of the World Climate Research Programme (WCRP). Phase 6 builds on previous phases executed under the leadership of the Program for Climate Model Diagnosis and Intercomparison (PCMDI) and relies on the Earth System Grid Federation (ESGF) and the Centre for Environmental Data Analysis (CEDA) along with numerous related activities for implementation. The original data is hosted and partially replicated on a federated collection of data nodes, and most of the data relied on by the IPCC is being archived for long-term preservation at the IPCC Data Distribution Centre (IPCC DDC) hosted by the German Climate Computing Center (DKRZ). The project includes simulations from about 120 global climate models and around 45 institutions and organizations worldwide. Summary: These data include the subset used by IPCC AR6 WGI authors of the datasets originally published in ESGF for 'CMIP6.AerChemMIP.HAMMOZ-Consortium.MPI-ESM-1-2-HAM' with the full Data Reference Syntax following the template 'mip_era.activity_id.institution_id.source_id.experiment_id.member_id.table_id.variable_id.grid_label.version'. The MPI-ESM1.2-HAM climate model, released in 2017, includes the following components: aerosol: HAM2.3, atmos: ECHAM6.3 (spectral T63; 192 x 96 longitude/latitude; 47 levels; top level 0.01 hPa), atmosChem: sulfur chemistry (unnamed), land: JSBACH 3.20, ocean: MPIOM1.63 (bipolar GR1.5, approximately 1.5deg; 256 x 220 longitude/latitude; 40 levels; top grid cell 0-12 m), ocnBgchem: HAMOCC6, seaIce: unnamed (thermodynamic (Semtner zero-layer) dynamic (Hibler 79) sea ice model). The model was run by the ETH Zurich, Switzerland; Max Planck Institut fur Meteorologie, Germany; Forschungszentrum Julich, Germany; University of Oxford, UK; Finnish Meteorological Institute, Finland; Leibniz Institute for Tropospheric Research, Germany; Center for Climate Systems Modeling (C2SM) at ETH Zurich, Switzerland (HAMMOZ-Consortium) in native nominal resolutions: aerosol: 250 km, atmos: 250 km, atmosChem: 250 km, land: 250 km, ocean: 250 km, ocnBgchem: 250 km, seaIce: 250 km.

Dataset Information This dataset presents long-term term indoor solar harvesting traces and jointly monitored with the ambient conditions. The data is recorded at 6 indoor positions with diverse characteristics at our institute at ETH Zurich in Zurich, Switzerland. The data is collected with a measurement platform [3] consisting of a solar panel (AM-5412) connected to a bq25505 energy harvesting chip that stores the harvested energy in a virtual battery circuit. Two TSL45315 light sensors placed on opposite sides of the solar panel monitor the illuminance level and a BME280 sensor logs ambient conditions like temperature, humidity and air pressure. The dataset contains the measurement of the energy flow at the input and the output of the bq25505 harvesting circuit, as well as the illuminance, temperature, humidity and air pressure measurements of the ambient sensors. The following timestamped data columns are available in the raw measurement format, as well as preprocessed and filtered HDF5 datasets: V_in - Converter input/solar panel output voltage, in volt I_in - Converter input/solar panel output current, in ampere V_bat - Battery voltage (emulated through circuit), in volt I_bat - Net Battery current, in/out flowing current, in ampere Ev_left - Illuminance left of solar panel, in lux Ev_right - Illuminance left of solar panel, in lux P_amb - Ambient air pressure, in pascal RH_amb - Ambient relative humidity, unit-less between 0 and 1 T_amb - Ambient temperature, in centigrade Celsius The following publication presents and overview of the dataset and more details on the deployment used for data collection. A copy of the abstract is included in this dataset, see the file abstract.pdf. L. Sigrist, A. Gomez, and L. Thiele. "Dataset: Tracing Indoor Solar Harvesting." In Proceedings of the 2nd Workshop on Data Acquisition To Analysis (DATA '19), 2019. Folder Structure and Files processed/ - This folder holds the imported, merged and filtered datasets of the power and sensor measurements. The datasets are stored in HDF5 format and split by measurement position posXX and and power and ambient sensor measurements. The files belonging to this folder are contained in archives named yyyy_mm_processed.tar, where yyyy and mm represent the year and month the data was published. A separate file lists the exact content of each archive (see below). raw/ - This folder holds the raw measurement files recorded with the RocketLogger [1, 2] and using the measurement platform available at [3]. The files belonging to this folder are contained in archives named yyyy_mm_raw.tar, where yyyy and mmrepresent the year and month the data was published. A separate file lists the exact content of each archive (see below). LICENSE - License information for the dataset. README.md - The README file containing this information. abstract.pdf - A copy of the above mentioned abstract submitted to the DATA '19 Workshop, introducing this dataset and the deployment used to collect it. raw_import.ipynb [open in nbviewer] - Jupyter Python notebook to import, merge, and filter the raw dataset from the raw/ folder. This is the exact code used to generate the processed dataset and store it in the HDF5 format in the processed/folder. raw_preview.ipynb [open in nbviewer] - This Jupyter Python notebook imports the raw dataset directly and plots a preview of the full power trace for all measurement positions. processing_python.ipynb [open in nbviewer] - Jupyter Python notebook demonstrating the import and use of the processed dataset in Python. Calculates column-wise statistics, includes more detailed power plots and the simple energy predictor performance comparison included in the abstract. processing_r.ipynb [open in nbviewer] - Jupyter R notebook demonstrating the import and use of the processed dataset in R. Calculates column-wise statistics and extracts and plots the energy harvesting conversion efficiency included in the abstract. Furthermore, the harvested power is analyzed as a function of the ambient light level. Dataset File Lists Processed Dataset Files The list of the processed datasets included in the yyyy_mm_processed.tar archive is provided in yyyy_mm_processed.files.md. The markdown formatted table lists the name of all files, their size in bytes, as well as the SHA-256 sums. Raw Dataset Files A list of the raw measurement files included in the yyyy_mm_raw.tar archive(s) is provided in yyyy_mm_raw.files.md. The markdown formatted table lists the name of all files, their size in bytes, as well as the SHA-256 sums. Dataset Revisions v1.0 (2019-08-03) Initial release. Includes the data collected from 2017-07-27 to 2019-08-01. The dataset archive files related to this revision are 2019_08_raw.tar and 2019_08_processed.tar. For position pos06, the measurements from 2018-01-06 00:00:00 to 2018-01-10 00:00:00 are filtered (data inconsistency in file indoor1_p27.rld). v1.1 (2019-09-09) Revision of the processed dataset v1.0 and addition of the final dataset abstract. Updated processing scripts reduce the timestamp drift in the processed dataset, the archive 2019_08_processed.tar has been replaced. For position pos06, the measurements from 2018-01-06 16:00:00 to 2018-01-10 00:00:00 are filtered (indoor1_p27.rld data inconsistency). v2.0 (2020-03-20) Addition of new data. Includes the raw data collected from 2019-08-01 to 2019-03-16. The processed data is updated with full coverage from 2017-07-27 to 2019-03-16. The dataset archive files related to this revision are 2020_03_raw.tar and 2020_03_processed.tar. Dataset Authors, Copyright and License Authors: Lukas Sigrist, Andres Gomez, and Lothar Thiele Contact: Lukas Sigrist (lukas.sigrist@tik.ee.ethz.ch) Copyright: (c) 2017-2019, ETH Zurich, Computer Engineering Group License: Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0/) References [1] L. Sigrist, A. Gomez, R. Lim, S. Lippuner, M. Leubin, and L. Thiele. Measurement and validation of energy harvesting IoT devices. In Design, Automation & Test in Europe Conference & Exhibition (DATE), 2017. [2] ETH Zurich, Computer Engineering Group. RocketLogger Project Website, https://rocketlogger.ethz.ch/. [3] L. Sigrist. Solar Harvesting and Ambient Tracing Platform, 2019. https://gitlab.ethz.ch/tec/public/employees/sigristl/harvesting_tracing Appears in the Proceedings of the 2nd Workshop on Data Acquisition To Analysis (DATA '19)