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description Publicationkeyboard_double_arrow_right Article , Other literature type , Journal 2021 United KingdomPublisher:MDPI AG Authors:Samuel Kwasi Opoku;
Samuel Kwasi Opoku
Samuel Kwasi Opoku in OpenAIREWalter Leal Filho;
Walter Leal Filho
Walter Leal Filho in OpenAIREFudjumdjum Hubert;
Fudjumdjum Hubert
Fudjumdjum Hubert in OpenAIREOluwabunmi Adejumo;
Oluwabunmi Adejumo
Oluwabunmi Adejumo in OpenAIREClimate change is a global problem, which affects the various geographical regions at different levels. It is also associated with a wide range of human health problems, which pose a burden to health systems, especially in regions such as Africa. Indeed, across the African continent public health systems are under severe pressure, partly due to their fragile socioeconomic conditions. This paper reports on a cross-sectional study in six African countries (Ghana, Nigeria, South Africa, Namibia, Ethiopia, and Kenya) aimed at assessing their vulnerabilities to climate change, focusing on its impacts on human health. The study evaluated the levels of information, knowledge, and perceptions of public health professionals. It also examined the health systems’ preparedness to cope with these health hazards, the available resources, and those needed to build resilience to the country’s vulnerable population, as perceived by health professionals. The results revealed that 63.1% of the total respondents reported that climate change had been extensively experienced in the past years, while 32% claimed that the sampled countries had experienced them to some extent. Nigerian respondents recorded the highest levels (67.7%), followed by Kenya with 66.6%. South Africa had the lowest level of impact as perceived by the respondents (50.0%) when compared with the other sampled countries. All respondents from Ghana and Namibia reported that health problems caused by climate change are common in the two countries. As perceived by the health professionals, the inadequate resources reiterate the need for infrastructural resources, medical equipment, emergency response resources, and technical support. The study’s recommendations include the need to improve current policies at all levels (i.e., national, regional, and local) on climate change and public health and to strengthen health professionals’ skills. Improving the basic knowledge of health institutions to better respond to a changing climate is also recommended. The study provides valuable insights which may be helpful to other nations in Sub-Saharan Africa.
International Journa... arrow_drop_down International Journal of Environmental Research and Public HealthOther literature type . 2021License: CC BYFull-Text: http://www.mdpi.com/1660-4601/18/9/4672/pdfData sources: Multidisciplinary Digital Publishing InstituteInternational Journal of Environmental Research and Public HealthArticle . 2021 . Peer-reviewedLicense: CC BYData sources: CrossrefInternational Journal of Environmental Research and Public HealthArticleLicense: CC BYData sources: UnpayWallInternational Journal of Environmental Research and Public HealthArticle . 2021Data sources: Europe PubMed Centrale-space at Manchester Metropolitan UniversityArticle . 2021Data sources: e-space at Manchester Metropolitan Universityadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.3390/ijerph18094672&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eumore_vert International Journa... arrow_drop_down International Journal of Environmental Research and Public HealthOther literature type . 2021License: CC BYFull-Text: http://www.mdpi.com/1660-4601/18/9/4672/pdfData sources: Multidisciplinary Digital Publishing InstituteInternational Journal of Environmental Research and Public HealthArticle . 2021 . Peer-reviewedLicense: CC BYData sources: CrossrefInternational Journal of Environmental Research and Public HealthArticleLicense: CC BYData sources: UnpayWallInternational Journal of Environmental Research and Public HealthArticle . 2021Data sources: Europe PubMed Centrale-space at Manchester Metropolitan UniversityArticle . 2021Data sources: e-space at Manchester Metropolitan Universityadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.3390/ijerph18094672&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Journal 2019Publisher:ENGG Journals Publications International Journa... arrow_drop_down International Journal of Engineering and TechnologyArticle . 2019 . Peer-reviewedData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.21817/ijet/2019/v11i2/191102053&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eumore_vert International Journa... arrow_drop_down International Journal of Engineering and TechnologyArticle . 2019 . Peer-reviewedData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.21817/ijet/2019/v11i2/191102053&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article 2022Publisher:Elsevier BV Tian Tian; Shengju Yin; Yongyan Chen; Chengrong Wang; Mengyuan Liu;Lei Jin;
Zhiwen Li;Lei Jin
Lei Jin in OpenAIREJufen Liu;
Yali Zhang; Linlin Wang;Jufen Liu
Jufen Liu in OpenAIREAiguo Ren;
Aiguo Ren
Aiguo Ren in OpenAIREpmid: 35780851
Chromium (Cr) exposure during gestation causes malformations in animal experiments. In this multicenter case-control study, we initially involved 130 orofacial clefts (OFCs) and 260 controls to assess the association between Cr concentration and risk for OFCs. Then, umbilical cord serum (49 vs. 119) and cord tissue (84 vs. 142) were used to validate the association between Cr and OFCs. We found that maternal serum Cr concentrations in OFC cases were significantly higher than those in controls. Compared with the lowest tertile of maternal serum Cr concentration, the highest tertile of Cr increased the risk for OFCs [OR = 2.14 (1.14-4.05)]. In the validation cohort of umbilical cord serum and tissue, higher concentrations of Cr were associated with increased risks for OFCs in a dose-dependent manner (all Ps for trends <0.05). Cr concentrations in maternal serum and cord serum showed a positive correlation. The Cr concentration in cord serum was inversely correlated with egg and milk consumption frequencies, and the Cr concentration in cord tissue was positively associated with indoor coal burning. In conclusion, prenatal Cr exposure is a risk factor for OFCs, and indoor coal burning during pregnancy may be one of the sources of Cr exposure.
add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.envres.2022.113799&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eumore_vert add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.envres.2022.113799&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Preprint , Journal 2022Embargo end date: 01 Jan 2021Publisher:Institute of Electrical and Electronics Engineers (IEEE) Authors: Ana Radovanovic;Bokan Chen;
Bokan Chen
Bokan Chen in OpenAIRESaurav Talukdar;
Binz Roy; +2 AuthorsSaurav Talukdar
Saurav Talukdar in OpenAIREAna Radovanovic;Bokan Chen;
Bokan Chen
Bokan Chen in OpenAIRESaurav Talukdar;
Binz Roy; Alexandre Duarte; Mahya Shahbazi;Saurav Talukdar
Saurav Talukdar in OpenAIREDatacenter power demand has been continuously growing and is the key driver of its cost. An accurate mapping of compute resources (CPU, RAM, etc.) and hardware types (servers, accelerators, etc.) to power consumption has emerged as a critical requirement for major Web and cloud service providers. With the global growth in datacenter capacity and associated power consumption, such models are essential for important decisions around datacenter design and operation. In this paper, we discuss two classes of statistical power models designed and validated to be accurate, simple, interpretable and applicable to all hardware configurations and workloads across hyperscale datacenters of Google fleet. To the best of our knowledge, this is the largest scale power modeling study of this kind, in both the scope of diverse datacenter planning and real-time management use cases, as well as the variety of hardware configurations and workload types used for modeling and validation. We demonstrate that the proposed statistical modeling techniques, while simple and scalable, predict power with less than 5% Mean Absolute Percent Error (MAPE) for more than 95% diverse Power Distribution Units (more than 2000) using only 4 features. This performance matches the reported accuracy of the previous started-of-the-art methods, while using significantly less features and covering a wider range of use cases.
IEEE Transactions on... arrow_drop_down https://dx.doi.org/10.48550/ar...Article . 2021License: arXiv Non-Exclusive DistributionData sources: Dataciteadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1109/tsg.2021.3125275&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eumore_vert IEEE Transactions on... arrow_drop_down https://dx.doi.org/10.48550/ar...Article . 2021License: arXiv Non-Exclusive DistributionData sources: Dataciteadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1109/tsg.2021.3125275&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Journal 2021Publisher:Springer Science and Business Media LLC Authors:Mohamed Samer;
Omar Hijazi;Mohamed Samer
Mohamed Samer in OpenAIREBadr A. Mohamed;
Badr A. Mohamed
Badr A. Mohamed in OpenAIREEssam M. Abdelsalam;
+4 AuthorsEssam M. Abdelsalam
Essam M. Abdelsalam in OpenAIREMohamed Samer;
Omar Hijazi;Mohamed Samer
Mohamed Samer in OpenAIREBadr A. Mohamed;
Badr A. Mohamed
Badr A. Mohamed in OpenAIREEssam M. Abdelsalam;
Essam M. Abdelsalam
Essam M. Abdelsalam in OpenAIREMariam A. Amer;
Ibrahim H. Yacoub;Mariam A. Amer
Mariam A. Amer in OpenAIREYasser A. Attia;
Heinz Bernhardt;Yasser A. Attia
Yasser A. Attia in OpenAIREBioplastics are alternatives of conventional petroleum-based plastics. Bioplastics are polymers processed from renewable sources and are biodegradable. This study aims at conducting an environmental impact assessment of the bioprocessing of agricultural wastes into bioplastics compared to petro-plastics using an LCA approach. Bioplastics were produced from potato peels in laboratory. In a biochemical reaction under heating, starch was extracted from peels and glycerin, vinegar and water were added with a range of different ratios, which resulted in producing different samples of bio-based plastics. Nevertheless, the environmental impact of the bioplastics production process was evaluated and compared to petro-plastics. A life cycle analysis of bioplastics produced in laboratory and petro-plastics was conducted. The results are presented in the form of global warming potential, and other environmental impacts including acidification potential, eutrophication potential, freshwater ecotoxicity potential, human toxicity potential, and ozone layer depletion of producing bioplastics are compared to petro-plastics. The results show that the greenhouse gases (GHG) emissions, through the different experiments to produce bioplastics, range between 0.354 and 0.623 kg CO2 eq. per kg bioplastic compared to 2.37 kg CO2 eq. per kg polypropylene as a petro-plastic. The results also showed that there are no significant potential effects for the bioplastics produced from potato peels on different environmental impacts in comparison with poly-β-hydroxybutyric acid and polypropylene. Thus, the bioplastics produced from agricultural wastes can be manufactured in industrial scale to reduce the dependence on petroleum-based plastics. This in turn will mitigate GHG emissions and reduce the negative environmental impacts on climate change.
Clean Technologies a... arrow_drop_down Clean Technologies and Environmental PolicyArticle . 2021 . Peer-reviewedLicense: Springer TDMData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1007/s10098-021-02145-5&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eumore_vert Clean Technologies a... arrow_drop_down Clean Technologies and Environmental PolicyArticle . 2021 . Peer-reviewedLicense: Springer TDMData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1007/s10098-021-02145-5&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Journal 2017 LuxembourgPublisher:Institute of Electrical and Electronics Engineers (IEEE) Authors:Hönes, C.;
Hackenberg, J.; Keller, R.; Zweigart, S.; +2 AuthorsHönes, C.
Hönes, C. in OpenAIREHönes, C.;
Hackenberg, J.; Keller, R.; Zweigart, S.; Fuchs, A.;Hönes, C.
Hönes, C. in OpenAIRESiebentritt, Susanne;
Siebentritt, Susanne
Siebentritt, Susanne in OpenAIREIn the search for a nontoxic replacement of the commonly employed CdS buffer layer for Cu(In,Ga)(S,Se) $_\mathrm{2}$ based solar cells, chemically deposited Zn(O,S) thin films are a most promising choice. In this paper, we address the usually slow deposition speed of Zn(O,S) in a newly developed ammonia-free chemical bath process, resulting in a deposition of 30 nm in 3 min with good homogeneity on 30 cm × 30 cm sized substrates. Solar cells with buffer layers prepared from this process match the efficiency of CdS reference cells. In a second step, we address the light-soaking post-treatment, still needed for maximum efficiencies. By addition of aluminum to the deposition process, the initial efficiencies can be increased slightly. With the addition of boron, the light-soaking post-treatment is rendered unnecessary, while maintaining high efficiencies above 15%, surpassing reference cells with CdS buffer.
IEEE Journal of Phot... arrow_drop_down Open Repository and Bibliography - LuxembourgArticle . 2017Data sources: Open Repository and Bibliography - LuxembourgIEEE Journal of PhotovoltaicsArticle . 2017 . Peer-reviewedLicense: IEEE CopyrightData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1109/jphotov.2017.2669360&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eumore_vert IEEE Journal of Phot... arrow_drop_down Open Repository and Bibliography - LuxembourgArticle . 2017Data sources: Open Repository and Bibliography - LuxembourgIEEE Journal of PhotovoltaicsArticle . 2017 . Peer-reviewedLicense: IEEE CopyrightData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1109/jphotov.2017.2669360&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Preprint , Journal 2021Embargo end date: 01 Jan 2021Publisher:Wiley Authors: Lars Q. English;Xuan-Lin Chen;
Xuan-Lin Chen; A. Mareno;Xuan-Lin Chen
Xuan-Lin Chen in OpenAIREWe begin by analyzing, using basic physics considerations, under what conditions it becomes energetically favorable to use aggressive regenerative braking to reach a lower speed over “coasting” where one relies solely on air drag to slow down. We then proceed to reformulate the question as an optimization problem to find the velocity profile that maximizes battery charge. Making a simplifying assumption on battery-charging efficiency, we express the recovered energy as an integral quantity, and we solve the associated Euler–Lagrange equation to find the optimal braking curves that maximize this quantity in the framework of variational calculus. Using Lagrange multipliers, we also explore the effect of adding a fixed-displacement constraint.
Mathematical Problem... arrow_drop_down Mathematical Problems in EngineeringArticle . 2021 . Peer-reviewedLicense: CC BYData sources: Crossrefhttps://dx.doi.org/10.48550/ar...Article . 2021License: arXiv Non-Exclusive DistributionData sources: Dataciteadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1155/2021/8002130&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eumore_vert Mathematical Problem... arrow_drop_down Mathematical Problems in EngineeringArticle . 2021 . Peer-reviewedLicense: CC BYData sources: Crossrefhttps://dx.doi.org/10.48550/ar...Article . 2021License: arXiv Non-Exclusive DistributionData sources: Dataciteadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1155/2021/8002130&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Preprint , Journal , Other literature type 2018Publisher:Institute of Electrical and Electronics Engineers (IEEE) Authors:Hajir Pourbabak;
Jingwei Luo;Hajir Pourbabak
Hajir Pourbabak in OpenAIRETao Chen;
Tao Chen
Tao Chen in OpenAIREWencong Su;
Wencong Su
Wencong Su in OpenAIREThis paper proposes a novel consensus-based distributed control algorithm for solving the economic dispatch problem of distributed generators. A legacy central controller can be eliminated in order to avoid a single point of failure, relieve computational burden, maintain data privacy, and support plug-and-play functionalities. The optimal economic dispatch is achieved by allowing the iterative coordination of local agents (consumers and distributed generators). As coordination information, the local estimation of power mismatch is shared among distributed generators through communication networks and does not contain any private information, ultimately contributing to a fair electricity market. Additionally, the proposed distributed algorithm is particularly designed for easy implementation and configuration of a large number of agents in which the distributed decision making can be implemented in a simple proportional-integral (PI) or integral (I) controller. In MATLAB/Simulink simulation, the accuracy of the proposed distributed algorithm is demonstrated in a 29-node system in comparison with the centralized algorithm. Scalability and a fast convergence rate are also demonstrated in a 1400-node case study. Further, the experimental test demonstrates the practical performance of the proposed distributed algorithm using the VOLTTRON platform and a cluster of low-cost credit-card-size single-board PCs. Comment: 16 Pages, 13 figures Figures order and references are corrected!
IEEE Transactions on... arrow_drop_down IEEE Transactions on Smart GridArticle . 2018 . Peer-reviewedLicense: IEEE CopyrightData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1109/tsg.2017.2699084&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eumore_vert IEEE Transactions on... arrow_drop_down IEEE Transactions on Smart GridArticle . 2018 . Peer-reviewedLicense: IEEE CopyrightData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1109/tsg.2017.2699084&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Other literature type , Journal 2016Publisher:Ivyspring International Publisher Funded by:NIH | DISEASE MODELING OF ALCOH...NIH| DISEASE MODELING OF ALCOHOL RELATED HEPATOCELLULAR CARCINOMA USING PATIENT IPSCSAuthors: Yoon Young Jang; Abhijeet Deshmukh; Lipeng Tian; Neha Prasad;Alcohol consumption has long been a global problem affecting human health, and has been found to influence both fetal and adult liver functions. However, how alcohol affects human liver development and liver progenitor cells remains largely unknown. Here, we used human induced pluripotent stem cells (iPSCs) as a model to examine the effects of alcohol, on multi-stage hepatic cells including hepatic progenitors, early and mature hepatocyte-like cells derived from human iPSCs. While alcohol has little effect on endoderm development from iPSCs, it reduces formation of hepatic progenitor cells during early hepatic specification. The proliferative activities of early and mature hepatocyte-like cells are significantly decreased after alcohol exposure. Importantly, at a mature stage of hepatocyte-like cells, alcohol treatment increases two liver progenitor subsets, causes oxidative mitochondrial injury and results in liver disease phenotypes (i.e., steatosis and hepatocellular carcinoma associated markers) in a dose dependent manner. Some of the phenotypes were significantly improved by antioxidant treatment. This report suggests that fetal alcohol exposure may impair generation of hepatic progenitors at early stage of hepatic specification and decrease proliferation of fetal hepatocytes; meanwhile alcohol injury in post-natal or mature stage human liver may contribute to disease phenotypes. This human iPSC model of alcohol-induced liver injury can be highly valuable for investigating alcoholic injury in the fetus as well as understanding the pathogenesis and ultimately developing effective treatment for alcoholic liver disease in adults.
add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.7150/ijbs.15811&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eumore_vert add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.7150/ijbs.15811&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Journal 2021Publisher:Elsevier BV Authors:Florian Laggner;
Florian Laggner
Florian Laggner in OpenAIREZ.A. Xing;
Olivier Izacard;Z.A. Xing
Z.A. Xing in OpenAIREEgemen Kolemen;
+2 AuthorsEgemen Kolemen
Egemen Kolemen in OpenAIREFlorian Laggner;
Florian Laggner
Florian Laggner in OpenAIREZ.A. Xing;
Olivier Izacard;Z.A. Xing
Z.A. Xing in OpenAIREEgemen Kolemen;
Egemen Kolemen
Egemen Kolemen in OpenAIREAndrew Nelson;
Andrew Nelson;Andrew Nelson
Andrew Nelson in OpenAIRECoupling between the UEDGE (edge fluid model), GINGRED (grid generation) and CAKE (equilibrium reconstruction) codes opens the door for automated interpretative scrape-off-layer (SOL) analysis over entire discharges, providing information that is essential in efforts to couple the SOL to core transport codes. In this work, we utilize new developments in the autoUEDGE code (Izacard et al. 2018) to investigate the behavior of the DIII-D SOL during the temporal evolution of an edge-localized mode (ELM) cycle. Modeled temperature and density profiles in UEDGE are automatically matched to experimental measurements by iteratively and self-consistently adjusting transport coefficient profiles in the plasma edge. This analysis is completed over multiple ELM cycles of a well-diagnosed discharge with long (∼100ms) inter-ELM periods. Directly after the ELM crash, a short period of high-density, low-temperature conditions is observed in Langmuir probe measurements at the outer divertor. This regime is associated with enhanced Dαemission and incident particle flux, suggesting that the divertor enters a period of high recycling after an ELM crash. After about ∼25ms, divertor conditions return to their pre-ELM conditions and remain there for several tens of milliseconds. Using the autoUEDGE code, the SOL is modeled as a function of ELM cycle using upstream profiles as input. The 2D modeling successfully reproduces both divertor Thomson scattering measurements and the experimentally observed divertor dynamics. Though the recycling is kept fixed throughout the modeling, changes in particle fluxes are consistent with local experimental recycling changes induced by ELMs. Agreement between modeling and observation suggests a strong link between upstream profiles and the high-recycling divertor conditions directly following large type-I ELMs.
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