Against the backdrop of the irreversible and systematic destruction of ecosystems, necessary for the survival and quality of life of people and non-human species, caused by human agency and socio-economic structures, we explore the opportunities and challenges to resist ecocide in relation to socio-economic inequality and the crisis of democracy. To this end, first section focuses on the diagnosis of ecocide. We show that due to three fallacies the connection between ecocide, socio-economic inequality and the crisis of democracy is not sufficiently accentuated. In the second section, several contemporary political measures to deal with ecocide are critically examined. We will argue that Agenda 2030, the Sustainable Development Goals, is part of the problem as it falsely assumes the compatibility of sustainability and economic growth. Finally, in the third section, the opportunities and challenges of resistance to ecocide are discussed with an emphasis on the power asymmetries between the Global North (GN) and the GS.