AbstractGlyptostrobus pensilis(Cupressaceae) is the only surviving species of the genusGlyptostrobus. Although the species is widely cultivated throughout China, in the wild it only occurs as small stands in southeastern China, central Laos, and southern Vietnam. However, its low genetic variability, lack of recruitment, and the progressive destruction of its habitat caused by humans, have meant that the populations are showing a clear declining trend and the species as a whole is threatened. Ecological niche modeling is used here to study the present potential distribution, as well as in the future (2061–2080) using several global circulation models under two of the shared socioeconomic pathways (SSP 126 and SSP 585) that are being used to produce the IPCC Sixth Assessment Report. The current potential area ofG. pensilisis of 1,452,481 km2with the areas of greatest probability of presence located in southeastern China. This potential area is reduced for the future according to most models, with greater losses for the SSP 585 scenario. Between 6.9 and 31.3% of all wild populations ofG. pensiliswould be outside potential areas (including the Lao populations, which harbor the highest levels of genetic variability). Conservation measures include the expansion of the current network of protected areas (since over 90% of wild populations do not occur within them), the development of propagation techniques, and the carrying out of translocation activities that should require international collaboration among the countries in which the species is found. With the current knowledge, we have reassessed the threat status of the species under the IUCN criteria, downgrading it from CR to EN both for China and at global level.