Abstract This article reviews the current status of research on urban green and blue infrastructure (GBI) in developing countries. We critically analyzed a total of 283 papers addressing urban GBI in selected developing countries in Africa, Asia, Latin America and the Caribbean (LAC), published between 2015 and 2019. The review aimed to a) analyze publication trends and typologies of urban GBI; b) identify innovative problem-solving measures using urban GBI, and c) understand priorities, differences and similarities in the deployment of urban GBI between the regions. The article identifies a growing interest in the urban GBI concept in the Global South, with a focus on local sustainable development. Urban GBI aims to address issues of urban greenery, land use policies, food security and poverty alleviation. There is a large variation in the number of articles across regions, with Asia, and particularly China, as the subject having a much larger number of publications when compared to LAC and Africa. We found that the focus of research topics varied between regions, reflecting regional development needs, so that urban agriculture research predominated in Africa, and green spaces and parks in Asia and LAC. GBI is still not implemented as a low-impact development or innovative strategy, except in China, where researchers have examined several cases of systemic GBI use for addressing urban issues. More recently, studies began exploring the linkages between nature and cities in light of global environmental issues such as biodiversity loss and climate change. We conclude with recommendations to further examine empirical evidence of urban GBI deployment and its outcomes in the Global South, that could contribute toward conceptualizing natural resource management in a multi-scalar, multi-dimensional, and multidisciplinary framework.