Background: Migration from Latin America to the US has been increasing over the past few decades. Migrants may experience structural and environmental vulnerabilities that increase their risk for negative impacts of climate change upon resettlement. This pilot study examined these determinants of health for Latin American immigrants in Atlanta. Methods: Between May and December 2021, Latin American immigrants were recruited to complete a questionnaire, with a subset completing an in-depth interview. Questionnaire results were analyzed descriptively, and interview responses were analyzed using grounded theory analysis. Results: Fifty-four participants from 11 countries were enrolled and were majority female (87 %), ranging in age from 20 to 72. Length of time in the US varied with 48 % living here for over 15 years. Challenges with structural and environmental determinants of health included running out of medication (54 % of those on daily medication) or food (37 %), household pests (40 %), trouble paying utility bills (31 %), mold (17 %), and no air conditioning (10 %). Only 33 % stated they could easily satisfy their material needs. Fifty-four percent had an emergency plan, while 65 % knew how to find out about emergency alerts. Qualitative analysis identified language barriers, access to healthcare, and poor mental health as common challenges. Social support was a potential factor of resilience. Conclusion: Our findings underscore the influence of social and environmental determinants of health on climate resilience in Atlanta-area immigrants and may inform migrant-focused organizations in providing resources to this community and supporting climate adaptation to safeguard health in this at-risk population.