About 25 million tons of food go wasted or lost in Iran which has socio-economic and environmental consequences for both the country and the households. The main objective of this research is to develop a model to examine the relationship between FCM components and the amount of FW of households in Tehran city, with a focus on urban women. By means of a structural model, this study provides a novel approach to exploring relationships between the food-related behavior of urban households and waste control (n = 1197). Besides, this study is the first attempt to quantify food waste in Iran at the household level. According to the adopted self-reporting procedure, in Tehran, every consumer wastes about 27.6 kg of edible food annually. It is found that households with better food consumption management (FCM (have a lower level of food waste. Moreover, the results have proved that other determinants such as demographic factors, economic power, information use, ability, and motivation have direct and indirect significant effects on FCM as well as on the amount of food waste generation. The findings suggest that the above-mentioned determinants are crucial and should be considered when developing a strategically sustainable food waste prevention plan.