In the framework of the study, the authors consider conceptual approaches to improve the management system of agrarian sphere development of regions in the realities of this industry functioning in the Russian Federation. Agrarian sphere is shown in aspects of socio-economic territorial system with its subsystems. The transition mechanisms of the agrarian sphere to the rails of sustainable development due to the choice of priority development directions within the life cycle are presented. The necessity of applying an integrated approach to the solution of industrial and social problems of the agricultural sector of the country is proved and reasoned.