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Drink and Think: Impact of Alcohol on Cognitive Functions and Dementia – Evidence of Dose-Related Effects

pmid: 28950395
AbstractRegular alcohol consumption affects cognitive performance and the development of dementia. So far, findings are contradicting, which might be explained in part by dose-related effects. For this narrative review, we undertook a literature search for surveys investigating the impact of alcohol consumption on cognitive performance and the development of dementia. The majority of studies observed a U-shaped relationship between regular alcohol consumption and cognitive function: frequent heavy consumption of alcohol alters brain functions and decreases cognitive performance; regular light and moderate consumption may have protective impact. In many studies, total abstainers show an inferior cognitive performance than people with moderate or light consumption. Nevertheless, policy implications are difficult to draw for at least 2 reasons: (1) the possible risks associated with alcohol consumption and (2) the potential confounders in the group of non-consumers and heavy consumers.
- Helmholtz Association of German Research Centres Germany
- German Center for Neurodegenerative Diseases Germany
- National Institute On Alcohol Abuse and Alcoholism United States
- Charité - University Medicine Berlin Germany
- National Institutes of Health United States
epidemiology [Cognition Disorders], chemically induced [Dementia], Alcohol Drinking, Ethanol, toxicity [Ethanol], epidemiology [Alcohol Drinking], epidemiology [Dementia], physiopathology [Alcohol Drinking], chemically induced [Cognition Disorders], Risk Factors, adverse effects [Alcohol Drinking], Humans, Dementia, Cognition Disorders, ddc: ddc:610
epidemiology [Cognition Disorders], chemically induced [Dementia], Alcohol Drinking, Ethanol, toxicity [Ethanol], epidemiology [Alcohol Drinking], epidemiology [Dementia], physiopathology [Alcohol Drinking], chemically induced [Cognition Disorders], Risk Factors, adverse effects [Alcohol Drinking], Humans, Dementia, Cognition Disorders, ddc: ddc:610
citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).37 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Top 10% influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Top 10% impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Top 10%
