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Methanol Levels in Saliva--A Non-Invasive Parameter That May Be Useful in Detection of Alcohol Intoxication

descriptionPublicationkeyboard_double_arrow_right Article , Journal 21 Jan 2010 Germany Publisher:Oxford University Press (OUP)Journal:Alcohol and Alcoholism, volume 45, pages 126-127 (issn: 0735-0414, eissn: 1464-3502,

Authors: Johannes Kornhuber; Stefan Bleich; Stefan Bleich; Bernd Lenz; Thomas Hillemacher; Thomas Hillemacher; Annemarie Heberlein; +2 Authors

doi: 10.1093/alcalc/agq003

pmid: 20093712

Methanol Levels in Saliva--A Non-Invasive Parameter That May Be Useful in Detection of Alcohol Intoxication

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Abstract

Non-invasive screening parameters proving alcohol intoxication are necessary especially in forensic contexts. Results obtained by common measurement methods like the ethanol breath analyzer may be falsified by several parameters like hypoventilation. Therefore, we undertook a pilot study investigating the usefulness and applicability of methanol levels measured in saliva. Our results show that methanol levels in saliva are closely linked to ethanol levels in saliva (r = 0.971, P < 0.0001, t = 5.622, P = 0.000) as well as to ethanol levels in serum (r = 0.786, P = 0.001, t = -1.106, P = 0.058). Therefore, methanol levels measured in saliva might be applicable in order to increase the validity of other non-invasive measurement methods like the ethanol breath analyzer.

Country

Germany

Related Organizations

University of Göttingen
Germany
Hannover Medical School
Germany
University of Erlangen-Nuremberg
Germany

Keywords

Adult, Male, Ethanol, Methanol, Middle Aged, Rehabilitation Centers, Alcoholism, Breath Tests, Predictive Value of Tests, Humans, Mass Screening, Female, Saliva, Alcoholic Intoxication

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	citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	11
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	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Average
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Average