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Alcoholism Clinical and Experimental Research
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Alcoholism Clinical and Experimental Research
Article . 2011 . Peer-reviewed
License: Wiley TDM
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Article . 2011
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Alcoholism Clinical and Experimental Research
Article . 2011
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Alcoholism Clinical and Experimental Research
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Adolescent Binge Drinking Alters Adult Brain Neurotransmitter Gene Expression, Behavior, Brain Regional Volumes, and Neurochemistry in Mice

ADULT BRAIN FOLLOWING ADOLESCENT BINGE
descriptionPublicationkeyboard_double_arrow_right Article , Journal 11 Jan 2011Publisher:WileyJournal:Alcoholism: Clinical and Experimental Research, volume 35, pages 671-688 (issn: 0145-6008, Copyright policy )
Authors: Jun He; Fulton T. Crews; Martin Styner; Joohwi Lee; Leon G. Coleman;

doi: 10.1111/j.1530-0277.2010.01385.x , 10.17615/xdf7-tq59

pmid: 21223304

pmc: PMC3544413

Adolescent Binge Drinking Alters Adult Brain Neurotransmitter Gene Expression, Behavior, Brain Regional Volumes, and Neurochemistry in Mice

Abstract

Binge-drinking is common in human adolescents. The adolescent brain is undergoing structural maturation and has a unique sensitivity to alcohol neurotoxicity. Therefore, adolescent binge ethanol may have long-term effects on the adult brain that alter brain structure and behaviors that are relevant to alcohol use disorders.

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Keywords

Male, Neurons, Aging, Neurotransmitter Agents, Alcohol Drinking, Ethanol, Dopamine, Receptors, Dopamine D4, Brain, Central Nervous System Depressants, Gene Expression, Motor Activity, Choline O-Acetyltransferase, Mice, Animals, Nervous System Physiological Phenomena, Maze Learning, Alcohol-Related Disorders

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