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Adult respiratory distress syndrome from overdose of tricyclic antidepressants.

descriptionPublicationkeyboard_double_arrow_right Article , Journal 01 Mar 1989Publisher:Radiological Society of North America (RSNA)Journal:Radiology, volume 170, pages 667-670 (issn: 0033-8419, eissn: 1527-1315,

Authors: Michael L. Richardson; J. D. Godwin; J M Vincent; R M Varnell;

doi: 10.1148/radiology.170.3.2916020

pmid: 2916020

Adult respiratory distress syndrome from overdose of tricyclic antidepressants.

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Abstract

Adult respiratory distress syndrome (ARDS) from overdose of tricyclic antidepressants (TCA) has been reported but is not well known. During a 1-year period, 81 patients with serious overdose from tranquilizers and other psychotropic drugs were examined. TCA alone induced overdose in 30 patients or were combined with other drugs in 26 patients. Twenty-five (31%) patients had overdose from drugs other than TCA. Chest radiography revealed that 30 (54%) patients with TCA overdose and six (24%) patients with non-TCA overdose had abnormalities. Clinical and radiographic findings consistent with ARDS were noted in five (9%) patients with TCA overdose and none of the patients with non-TCA overdose. Five patients with TCA overdose and one (4%) patient with non-TCA overdose had interstitial edema that never progressed to ARDS. TCA should be added to the list of drugs associated with the development of ARDS.

Related Organizations

Washington State University
United States
University of Mary
United States

Keywords

Psychotropic Drugs, Respiratory Distress Syndrome, Ethanol, Antidepressive Agents, Tricyclic, Pneumonia, Aspiration, Radiography, Tranquilizing Agents, Humans, Lung

Impact byBIP!

	citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	42
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	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Top 10%
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Top 10%