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Chronic Starvation Impairs the Effect of Depressant Drugs on CNS of Rats

descriptionPublicationkeyboard_double_arrow_right Article , Journal 01 Jan 1981 Brazil Publisher:S. Karger AGJournal:Pharmacology, volume 23, pages 64-68 (issn: 0031-7012, eissn: 1423-0313,

Authors: Masur, J.; Ribeiro, M. J.;

doi: 10.1159/000137529

pmid: 7312938

Chronic Starvation Impairs the Effect of Depressant Drugs on CNS of Rats

- Summary
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Abstract

Rats starved for 70 days, i.e. receiving 60% of food ingested by control rats, showed a shortened sleeping time after ethanol and pentobarbital and a reduction of the catatonic response to haloperidol. Conversely, acute 24 h food deprivation increased barbiturate and ethanol sleeping time but did not effect the catatogenic action of haloperidol.

Country

Brazil

Related Organizations

Universidade Federal de São Paulo (UNIFESP)
Brazil
Universidade de São Paulo
Brazil
Universidade Federal de São Paulo
Brazil

Keywords

Male, Ethanol, Brain, Central Nervous System Depressants, Rats, Inbred Strains, Rats, Starvation, Animals, Haloperidol, Sleep, Pentobarbital

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