The lack of real integration between the different dimensions of sustainability is highlighted in the literature as one of the main hindrances to lessening the environmental risks and impacts of large-scale development projects. This paper discusses a hypothesis concerning the problems of integration between the different dimensions of sustainability in socio-environmental research into such projects. Differences in modes of knowledge production and the relationships of these with prevailing social positions constitute the crux of the argument. Endeavours to improve translational knowledge and mixed research methodologies (seeking the semi-standardization of research processes) are put forward as approaches to overcoming the above-mentioned obstacles.